Antifungal activities of Medinilla speciosa Blume fruit extracts against Candida albicans and Trichophyton rubrum

Abstract

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Isolation, Carbohydrate Metabolism Profile, and Molecular Identification of Plant-Derived Lactic Acid Bacteria from Musa acuminata x balbisiana and Medinilla cummingii Naudin

“…25 The diversity of the Medinilla genus is prominent in the Philippines and is commonly found in lowland rainforests and montane forests, with some species also occurring in mossy forests and ultramafic forest. [26][27] Several species of Medinilla have been used as traditional medicine in various Asian countries and were tested for active phytochemical compounds with antimicrobial and antifungal properties [28][29] . There are currently no available data on published journal articles regarding the presence of LAB in Medinilla species found in the Philippines.…”

“…14 Several Medinilla species have undergone analysis for active phytochemical compounds antimicrobial, and antifungal properties prior to their use as traditional medicine in various Asian countries. [15][16] However, current scientific literature has given scant attention to the utilization of floral components of plants as an unconventional reservoir of LAB despite considerable research characterizing LAB…”

REVIEW ARTICLE: AKTIVITAS FARMAKOLOGI TANAMAN PARIJOTO (Medinilla speciosa)

“…Ekstrak etanol 70% buah parijoto dengan konsentrasi 10% mempunyai zona hambat sebesar 28,03 mm, sedangkan ekstrak etanol 96% dengan konsentrasi 10% memiliki daya hambat sebesar 36,11 mm terhadap C. albicans [15]. Ekstrak etil asetat buah parijoto dengan kadar konsentrasi 20% mempunyai daya hambat sebesar 13,60 mm, sedangkan ekstrak methanol konsentrasi 20% mempunyai daya hambar sebesar 22,22 mm terhadap T. Rubrum [16].…”

“…Buah parijoto mengandung senyawa flavonoid, alkaloid, tanin, saponin, dan kuinon [16]. Senyawa flavonoid mempunyai mekanisme kerja dengan mendenaturasi protein yang meningkatkan sel permeabilitas, sehingga merusak sel jamur dan akhirnya mengalami lisis.…”