Antifungal Activity of Ajawain Seeds ( Trachyspermum ammi )

Khan, Nida Tabassum; Jameel, Namra

doi:10.4172/2167-7956.1000164

Cited by 4 publications

(2 citation statements)

References 21 publications

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“…Garlic and omam, the common culinary herbs, contain a wide array of compounds and various kinds of biological activity and hence they are being explored for the treatments of various ailments nowadays. [ 13 14 ] Antimicrobial activities of garlic[ 15 ] and omam[ 16 17 18 ] are also documented against various human pathogen, In this line the present study finds them as against M. circinelloides and comparable with the activity of Amphotericin B. Further, it is observed that though MICs of both the extracts are differing against the pathogen, both are promising and it may be due to the different constituents present in them.…”

Section: Discussionsupporting

confidence: 66%

Inhibitory effect of garlic and omam extracts on Mucor circinelloides, a fungus causing mucormycosis

Nataraj

Nimoshini

Rameshkumar

et al. 2023

Journal of Oral and Maxillofacial Pathology

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Context: Mucor circinelloides is reported to be the second among the most common causative agents of emerging mucormycosis. It is intrinsically resistant to most known antifungals. Further the use of antifungals cause side effects. Traditional knowledge system for treating various ailments is stronger in India and it also backs deriving various bioactive compounds from herbal sources, in the modern system of medicine. Therefore, two most commonly used culinary herbal materials viz., ginger and omam were studied in vitro against M. circinelloides , as an alternate to antifungal drugs. Aims: To explore the traditional herbal resources as alternate to Amphotericin B to use against M. circinelloides , a fungus causing mucormycosis. Methods and Material: Aqueous extracts of garlic and omam were prepared and tested against M. circinelloides , at different concentrations. A positive control with Amphotericin B and negative control without any supplements were also maintained. The inhibitory effect was assessed by adopting optical density (OD) measurement method in SD broth and SD Agar Well Plate using spore suspension as inoculum. Statistical Analysis Used: Paired student T test was employed using SPSS Version 1.6. Results and Conclusions: Both garlic and omam extracts were found to inhibit the M. circinelloides and their MICs were 600 and 700 μL/mL. It is comparable with the MIC of Amphotericin B, 200 μg/mL. Thus, the regular use of garlic and omam can reduce the risk of possible mucormycosis and these herbs can be explored for drug formulations against M. circinelloides .

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Section: Discussionsupporting

confidence: 66%

Inhibitory effect of garlic and omam extracts on Mucor circinelloides, a fungus causing mucormycosis

Nataraj

Nimoshini

Rameshkumar

et al. 2023

Journal of Oral and Maxillofacial Pathology

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“…Thymol is the major phenolic compound of T . ammi and p ‐cymene and y‐terpinene (Tabassum Khan and Jameel 2018). The main bioactive compounds of N. sativa include thymoquinone, p‐cymene, α‐thujene, longifolene, β‐pinene, α‐pinene and carvacrol (Shokri 2016).…”

Section: Discussionmentioning

confidence: 99%

Antifungal and antioxidant activity of two essential oils and Lactococcus lactis subsp. lactis extract on selected Iranian white cheese‐contaminating fungi

Shojaee

Anvar

Hamedi

et al. 2022

Int J of Dairy Tech

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Cheese is generally susceptible to contamination by fungal spoilage organisms. The application of essential oils (EOs) as preservatives in dairy products has been growing recently. Thus, they need to be tested for various interactions before being used in cheese production processes. The aim of this study was first to determine the antifungal and antioxidant effects of two EOs and Lactococcus lactis subsp. lactis extract (Ex) against three spoilage fungi; and second to evaluate EOs/Ex, alone and in combination, on inoculated cheese samples. The combination of EOs and Ex revealed a significant decrease in microbial load and higher antioxidant activity compared with the control samples.

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Antioxidants in Spices: A Review of the Antioxidant Components and Properties of Some Common African Spices and Their Role in Human Nutrition and Plant–Microbe Interactions

Oluwole

Ademuyiwa

2021

Antioxidants in Plant-Microbe Interaction

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Antifungal Activity of Ajawain Seeds ( Trachyspermum ammi )

Cited by 4 publications

References 21 publications

Inhibitory effect of garlic and omam extracts on Mucor circinelloides, a fungus causing mucormycosis

Inhibitory effect of garlic and omam extracts on Mucor circinelloides, a fungus causing mucormycosis

Antifungal and antioxidant activity of two essential oils and Lactococcus lactis subsp. lactis extract on selected Iranian white cheese‐contaminating fungi

Antioxidants in Spices: A Review of the Antioxidant Components and Properties of Some Common African Spices and Their Role in Human Nutrition and Plant–Microbe Interactions

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