Antifungal activity of plant extracts against <i>Colletotrichum lagenarium</i>, the causal agent of anthracnose in cucumber

Chen, Yijuan; Dai, Guanghui

doi:10.1002/jsfa.5565

Cited by 55 publications

(41 citation statements)

References 35 publications

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“…Besides yield losses and food decay, fungi also pose a serious risk for consumers because of dangerous secondary metabolites [16]. Therefore, the control of pathogenic fungi is urgent and important.…”

Section: Discussionmentioning

confidence: 99%

Antifungal activity of Momordica charantia seed extracts toward the pathogenic fungus Fusarium solani L.

Wang

Zheng

Xiang

et al. 2016

Journal of Food and Drug Analysis

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Momordica charantia L., a vegetable crop with high nutritional value, has been used as an antimutagenic, antihelminthic, anticancer, antifertility, and antidiabetic agent in traditional folk medicine. In this study, the antifungal activity of M. charantia seed extract toward Fusarium solani L. was evaluated. Results showed that M. charantia seed extract effectively inhibited the mycelial growth of F. solani, with a 50% inhibitory rate (IC) value of 108.934 μg/mL. Further analysis with optical microscopy and fluorescence microscopy revealed that the seed extract led to deformation of cells with irregular budding, loss of integrity of cell wall, as well as disruption of the fungal cell membrane. In addition, genomic DNA was also severely affected, as small DNA fragments shorter than 50 bp appeared on agarose gel. These findings implied that M. charantia seed extract containing α-momorcharin, a typical ribosome-inactivating protein, could be an effective agent in the control of fungal pathogens, and such natural products would represent a sustainable alternative to the use of synthetic fungicides.

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Section: Discussionmentioning

confidence: 99%

Antifungal activity of Momordica charantia seed extracts toward the pathogenic fungus Fusarium solani L.

Wang

Zheng

Xiang

et al. 2016

Journal of Food and Drug Analysis

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“…The losses caused by plant pathogenic fungi have attracted wide attention throughout the world. For example, Phomopsis asparagi can cause stem blight of asparagus and subsequent yield loss; the premature plant death caused by Colletotrichum Lagenarium can lead to a yield loss of 6-48% (Chen & Dai, 2012;Elena, 2006). Therefore, three common plants-threatening fungi, C. Lagenarium, P. asparagi, and Fusarium oxysporum, were selected to evaluate the antifungal properties of the derivatives by hypha measurement in vitro.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, characterization, and antifungal activity of novel inulin derivatives with chlorinated benzene

Guo

Wang

et al. 2014

Carbohydrate Polymers

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a b s t r a c tA group of novel inulin derivatives containing benzene or chlorinated benzene were synthesized by reaction of chloracetyl inulin (CAIL) with the Schiff bases of 4-amino-pyridine, including (2-pyridyl)acetyl inulin chloride (PAIL), 2-[4-(2-chlorobenzylideneamino)-pyridyl]acetyl inulin chloride (2CPAIL), 2-[4-(4-chlorobenzylideneamino)-pyridyl]acetyl inulin chloride (4CPAIL), and 2-[4-(2,4-dichlorobenzylideneamino)-pyridyl]acetyl inulin chloride (2,4DCPAIL). Their antifungal activity against three kinds of phytopathogens was estimated by hypha measurement in vitro. Of all the synthesized chitosan derivatives, 2,4DCPAIL inhibited the growth of the tested phytopathogens with inhibitory indices of 67%, 47%, and 43% against Colletotrichum lagenarium (Pass) Ell.et halst, Phomopsis asparagi (Sacc.) Bubak and Fusarium oxysporum (schl.) F.sp. niveum (F. oxysporum) respectively at 1.0 mg/mL. The results indicate that all the inulin derivatives have better antifungal activity than inulin, and the inhibitory index is affected by the chlorine atom grafted to the inulin derivatives.

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“…Extracts from several species of the Cinnamomum have shown to be one of the most promising sources of new bio-efficacy against fungus [6, 7], bacteria [8] and insect pests [9], and compounds for treatment of infectious diseases [10], autoimmune diseases [11] and cancer [12]. There are few reports on molluscicidal activity of leaf extracts from C. camphora against O. hupensis [13, 14].…”

Section: Introductionmentioning

confidence: 99%

Linalool, derived from Cinnamomum camphora (L.) Presl leaf extracts, possesses molluscicidal activity against Oncomelania hupensis and inhibits infection of Schistosoma japonicum

et al. 2014

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BackgroundSchistosomiasis japonicum remains a considerable economic and public health concern in China, the Philippines and Indonesia. Currently available measures to control the unique intermediate host Oncomelania hupensis are frequently associated with severe side effects. Previous studies have demonstrated that linalool-rich extracts from various plants exhibited promising biological activities including cytotoxic, anti-microbial and anti-parasitic properties.MethodsWe identified the components of leaf extracts from Cinnamomum camphora by gas chromatography coupled to mass spectrometry (GC-MS) and investigated molluscicidal and larvicidal effects of linalool against O. hupensis and Schistosoma japonicium. The ultrastructural alterations in gills, salivary gland, stomach and hepatopancreas of snails were observed under the light microscope and transmission electron microscope, and lesions to tegument of cercaria were examined under a light microscope and fluorescence microscope. We then evaluated the effects of linalool on skin penetration and migration of schistosomula and adult survival by measurement of worm burden and egg counts in Balb/C mice infected with linalool-treated cercariae.ResultsIn the present work, 44 components were identified from the leaf extracts of C. camphora, of which linalool was the most abundant constituent. Linalool exhibited the striking molluscicidal and larvicidal effects with LC50 = 0.25 mg/L for O. hupensis and LC50 = 0.07 mg/L for cercaria of S. japonicium. After exposure to linalool, damage to the gills and hepatopancreas of the snails, and to the tegument and body-tail joint of cercariae was apparent. In addition, linalool markedly reduced the recovered schistosomulum from mouse skin after challenge infection, and therefore decreased the worm burden in infected animals, but not fecundity of female adults of the parasite.ConclusionsOur findings indicated that linalool might be a novel chemotherapeutic agent against S. japonicium and the snail intermediate host.

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Antifungal activity of plant extracts against Colletotrichum lagenarium, the causal agent of anthracnose in cucumber

Abstract: These results demonstrated that the extract from C. camphora could be used as a potent phytochemical fungicide.

Cited by 55 publications

References 35 publications

Antifungal activity of Momordica charantia seed extracts toward the pathogenic fungus Fusarium solani L.

Antifungal activity of Momordica charantia seed extracts toward the pathogenic fungus Fusarium solani L.

Synthesis, characterization, and antifungal activity of novel inulin derivatives with chlorinated benzene

Linalool, derived from Cinnamomum camphora (L.) Presl leaf extracts, possesses molluscicidal activity against Oncomelania hupensis and inhibits infection of Schistosoma japonicum

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