Antifungal Activity of Selected Medicinal Plants Used by Indigenous People of Assam in India to Treat Onychomycosis

Borgohain, Parismita; Barua, Purnima; Das, D.; Mahanta, Jagadish; Saikia, Bhaskar; Dutta, Pranab; Saikia, L. R.

doi:10.1080/10496475.2022.2034701

Cited by 4 publications

(3 citation statements)

References 21 publications

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“…AH with a lower water addition formed several alkane compounds such as 1‐tridecene, Z‐3‐heptadecene, and 3‐ethyl‐5‐(2‐ethylbutyl)‐octadecane, in addition to 1‐pentadecene and undecane, which were also formed at a higher water addition. All those formed compounds were identified as responsible for odour perception from medicinal plant extracts (Wang et al ., 2015; Borgohain et al ., 2022). In untreated BSG, only hexanoic acid was identified as a fatty acid, while AH (1:1) formed hexanoic acid and hexanoic acid 1‐cyclopentyl‐ethyl ester.…”

Section: Resultsmentioning

confidence: 99%

Chemical compositions, antioxidant activities and techno‐functionality of spent grain treated by autoclave treatment: evaluation of water and temperature levels

Naibaho

Bobak

Pudło

et al. 2022

Int J of Food Sci Tech

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Summary Autoclave heating (AH) has been applied to modify the dietary fibre composition of dried brewers' spent grain (BSG) flour, which required multiple drying processes. The current study aimed to investigate the influence of the thermal levels and water ratio on AH, as an alternative, in altering the chemical compositions, antioxidant properties, and functionality of undried fresh BSG. The results showed that AH converted the saturated fatty acids into polyunsaturated fatty acids. AH reduced ketones and furans regardless of the water ratio while the amounts of aldehydes, alcohols, alkenes, and fatty acids depended on the water ratio. The elimination and formation of several volatile compounds were identified due to the AH depending on the water ratio. The total flavan‐3‐ols, antioxidant activities, and water‐holding capacity of BSG were improved as an impact of thermal elevation and regardless of the water ratio. In conclusion, AH treatment on fresh, undried BSG showed a beneficial performance in improving the quality of BSG for further valorisation as a value‐added by‐product.

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Section: Resultsmentioning

confidence: 99%

Chemical compositions, antioxidant activities and techno‐functionality of spent grain treated by autoclave treatment: evaluation of water and temperature levels

Naibaho

Bobak

Pudło

et al. 2022

Int J of Food Sci Tech

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“…This plant also helps to prevent onychomycosis. A previous study reported that leaves of Lawsonia innermis L. showed potent against Non-dermatophyte molds which are related to onychomycosis 87 .…”

Section: Informant Consensus Factor (Icf)mentioning

confidence: 98%

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2022

IJPSR

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Due to plentiful wild plant diversity, poor road conditions to connect modern medical facilities, and age-old folk knowledge on medicinal plants, the tribal communities of Dhemaji District, Assam, India, still practice traditional plant-based therapy in the management of primary healthcare. The present investigation aims to represent the ethnobotanical knowledge of different ethnic community peoples of the Nilakh-Sripani area, a fringe area laying the Assam-Arunachal border. The ethnobotanical field survey (2018-2020) was carried out based on formal and informal semi-structured questionnaires with village headmen, traditional healers, and well-educated persons from 11 villages belonging to Nilakh and Sripanigaon panchayat. Analysis of the demographic profile of informants, local names of plants, parts used, used in ailments, preparation and route of administration was investigated during the survey. The documented data were also quantitatively analyzed by using standard ethnobotanical parameters like Use Value (UV), Fidelity Level (FL) and Informant Consensus Factor (ICF). A total of 102 plant species belonging to 57 families were recorded. During the time of the study, 33 plant species having new ethnobotanical potential were recorded. Besides the uses of plant species in different human ailment categories, 8 plant species are reported in managing livestock diseases especially in poultries, pigs and cattle, and 2 species used as a bio-pesticide in the study area. The study further should be helpful for the valid discovery of a new active pharmaceutical ingredient (API) or drug formulation from natural origin. INTRODUCTION:In India, different tribal community people use more than 8000 medicinal plant species and approximately 25,000 folk medicine-based formulations of their traditional healthcare system 1 . The majority tribal community peoples of entire North-East India, i.e., more than 200 tribes of different ethnic groups, are inhabited in the forest ecosystem and have their sociocultural patterns, tradition, and specific food habits 2 .

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“…The main antifungal chemicals discovered by GC-MS/MS included azulene, 9-hexadecenoic acid, octadecane, and 3-ethyl-5-(2-ethyl butyl). C. tiglium is a viable option for the safe treatment of onychomycosis due to its wide spectrum of antifungal characteristics 10 . In general, nail lacquers sold as Amorolfine and Ciclopirox are utilized for the therapy.…”

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confidence: 99%