Antifungal efficacy of Punica granatum, Acacia nilotica, Cuminum cyminum and Foeniculum vulgare on Candida albicans: An in vitro study

Pai, Mithun; Prashant, GM; Murlikrishna, K S; Shivakumar, K. M.; Chandu, GN

doi:10.4103/0970-9290.70792

Cited by 75 publications

(31 citation statements)

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“…The procedure of aqueous decoction followed to prepare the extracts was based on a previous study by Pai et al . [8] Decoctions were prepared by boiling 10 g of the powder in 100 ml sterile distilled water over a low flame for 15 min. The flasks were then plugged and allowed to cool for 45 min.…”

Section: Methodsmentioning

confidence: 99%

Comparative evaluation of antimicrobial efficacy of an alternative natural agent for disinfection of toothbrushes

et al. 2017

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Objective:The aim of this study was to assess the antimicrobial potency of aqueous extract of Psidium guajava leaves in two different concentrations as a toothbrush disinfectant against three oral bacterial species.Materials and Methods:Aqueous extracts of P. guajava leaves were prepared at 20% and 30% concentrations and 0.2% chlorhexidine was used as control. The toothbrushes were equally divided into 9 groups with 10 toothbrushes per disinfectant, which were contaminated with Streptococcus mutans, Lactobacillus acidophilus, and Enterococcus faecalis. Microbial culture was done after 5 min and 3 h of decontamination.Results:Group Ia and Ib showed that the presence of E. faecalis was observed in 8 (40%) of 20 toothbrushes. Group IIa and IIb showed a significant reduction in colony forming unit/toothbrush during 3 h evaluation. Group IIIa and IIIb showed nil growth during 3 h evaluation. Nil growth was observed with the control group for all three organisms. Statistically significant values were obtained for 5 min (P < 0.001) and 3 h (P < 0.001) disinfection period against L. acidophilus at two different concentrations.Conclusion:Aqueous extracts of guava leaves can be used as an alternative organic product for disinfection of toothbrushes.

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Section: Methodsmentioning

confidence: 99%

Comparative evaluation of antimicrobial efficacy of an alternative natural agent for disinfection of toothbrushes

et al. 2017

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“…C. cyminum exhibits activities like estrogenic activity [157], hypolipidaemic activity [158], antinociceptive and anti-inflammatory activity [159], anticonvulsant effect [160], anticancer activity [161], antimicrobial activity [156, 162], antitussive effect [163], antioxidant activity [164], and antifungal activity [165]. The doses of its fractions responsible for the bioavailability enhancement activity ranged from 0.5 to 25 mg/kg body weight.…”

Section: Herbal Bioenhancersmentioning

confidence: 99%

A Comprehensive Review on Pharmacotherapeutics of Herbal Bioenhancers

Dudhatra

Mody

Awale

et al. 2012

The Scientific World Journal

169

117

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In India, Ayurveda has made a major contribution to the drug discovery process with new means of identifying active compounds. Recent advancement in bioavailability enhancement of drugs by compounds of herbal origin has produced a revolutionary shift in the way of therapeutics. Thus, bibliographic investigation was carried out by analyzing classical text books and peer-reviewed papers, consulting worldwide-accepted scientific databases from last 30 years. Herbal bioenhancers have been shown to enhance bioavailability and bioefficacy of different classes of drugs, such as antibiotics, antituberculosis, antiviral, antifungal, and anticancerous drugs at low doses. They have also improved oral absorption of nutraceuticals like vitamins, minerals, amino acids, and certain herbal compounds. Their mechanism of action is mainly through absorption process, drug metabolism, and action on drug target. This paper clearly indicates that scientific researchers and pharmaceutical industries have to give emphasis on experimental studies to find out novel active principles from such a vast array of unexploited plants having a role as a bioavailability and bioefficacy enhancer. Also, the mechanisms of action by which bioenhancer compounds exert bioenhancing effects remain to be explored.

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“…It's essential oil, which is produced by steam distillation of dried fruits, is used for flavoring purposes in Western countries [4]. Foeniculum vulgare seed and bark extracts have been reported to exhibit antifungal effect against candida species by inhibiting mycelial growth and germination of Sclerotinia sclerotiorum [5,6]. Thus could be used as effective bio fungicide against phytopathogenic fungi [7].…”

Section: Introductionmentioning

confidence: 99%

Antifungal Potency of Foeniculum vulgare Seed Extract

Khan¹

2017

J Tissue Sci Eng

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Foeniculum vulgare belongs to family Apiaceae and is also called by the name of fennel. Agar disc diffusion method was used to determine the antifungal activity of its seed extracts in water and methanol against a number of pathogenic fungi. Methanolic extract of fennel seeds was less effective against test fungi as compared to its aqueous extract. However in case of Candida species, both types of extracts were found to be effective.

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Antifungal efficacy of Punica granatum, Acacia nilotica, Cuminum cyminum and Foeniculum vulgare on Candida albicans: An in vitro study

Abstract: The results showed the potential use of these products as cheap and convenient adjuvants to pharmaceutical antifungal products.

Cited by 75 publications

References 1 publication

Comparative evaluation of antimicrobial efficacy of an alternative natural agent for disinfection of toothbrushes

Comparative evaluation of antimicrobial efficacy of an alternative natural agent for disinfection of toothbrushes

A Comprehensive Review on Pharmacotherapeutics of Herbal Bioenhancers

Antifungal Potency of Foeniculum vulgare Seed Extract

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