Antihistaminic and Antianaphylactic Activity of Some α-Pyridinoethylenediamines

Metabolite Antagonists.

“…doses of histamine. A series of closely related compounds was investigated by Mayer, Huttrer, and Scholz (284,285), who found that iV-(2-pyridyl)-A"-benzyl-iV,-dimethyletlydenediamine (VI) ivas the most active member of the group (table 11). Secondary amines were all inactive or almost inactive.…”

Physical Medicine and Rehabilitation in the Prevention of Chronic Invalidism

“…Bed rest leads to the deconditioning of the body as a whole. 6 Thus, the functional status of organ systems not directly involved in the lesions being treated may deteriorate so significantly as to induce a chronic invalidism which will delay resumption of activity for a considerable interval beyond that recpiired to return diseased or injured tissues to normal. Although nature unaided may eventually restore func¬ tional capacity to previous levels characteristic of the individual patient, this does not necessarily follow, or the restoration is attained at a rate below optimal.…”