Antiinflammatory activity of Solanum trilobatum

Methyl jasmonate elicits the solasodine production and anti-oxidant activity in hairy root cultures of Solanum trilobatum L.

“…Previous pharmacological investigations have elucidated broad biological activities of the plant such as anti-bacterial, anti-fungal, anti-tumor, anti-oxidant, anti-inflammatory, anti-diabetic etc. (Mohanan and Devi, 1997;Emmanuel et al, 2006;Doss et al, 2009). The plant possesses economically valuable glycoalkaloids such as solasodine, ␤ solamarine etc., as its bioactive phytoconstituents (Balakrishna et al, 1992).…”

Chemoprotective Effect of Sobatum against Lithium-Induced Oxidative Damage in Rats

“…[6] It was also reported that S. trilobatum possesses anti-inflammatory, anti-ulcerogenic, and antimicrobial activities. [78] In our laboratory, sobatum has been isolated and purified to homogeneity from herb S. trilobatum and believed to be an active principle responsible for its beneficial action on vital organs. Earlier studies proved that sobatum has the antitumor property and produce no toxicities.…”

Solanum trilobatumin the management of atopy: Through inhibition of mast cell degranulation and moderation of release of interleukins

“…The in vitro-in vivo concordance in the result proves that S. trilobatum has anti-allergic properties. Studies have been carried out in the past to establish anti-inflammatory and anti-oxidant properties of S. trilobatum ,[15–20] but its antihistaminic property, in particular, is a novel finding of this present investigation.…”