Antiinflammatory activity of some medicinal plant extracts from Venezuela

Abad, M.J.; Bermejo, Paulina; Carretero, E.; Martínez-Acitores, C.; Noguera, B.; Villar, A.

doi:10.1016/s0378-8741(96)01478-x

Cited by 52 publications

(31 citation statements)

References 4 publications

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“…Extracts from several medicinal plants have been found to inhibit both acute and chronic phases of inflammation (Abad et al, 1996;Mostafa et al, 2010). The anti-inflammatory property observed for F. elastica bark extract could be due to the steroids such as cyclofuntumienol and cycloeucalenol present in the leaves and stem bark (Zirihi et al, 2005).…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial and anti-inflammatory properties ofFuntumia elastica

Agyare

Koffuor

Boakye

et al. 2013

Pharmaceutical Biology

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Section: Discussionmentioning

confidence: 99%

Antimicrobial and anti-inflammatory properties ofFuntumia elastica

Agyare

Koffuor

Boakye

et al. 2013

Pharmaceutical Biology

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“…In folk medicine, various indigenous drugs are used in single and/or in combined form to treat different types of inflammatory and arthritic conditions, with considerable success (13).…”

Section: Discussionmentioning

confidence: 99%

Anti-inflammatory and antispasmodic activity of Ipomoea imperati (Vahl) Griseb (Convolvulaceae)

Paula

Hayashi

Freitas

2003

Braz J Med Biol Res

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Ipomoea imperati (Convolvulaceae) lives on the sandy shores of the Brazilian coast and in other areas of the world. The anti-inflammatory activity of a methanol-water extract of the leaves of I. imperati was investigated in experimental models of acute and subchronic inflammation. Topical application of the extract (10 mg/ear) inhibited mouse ear edema induced by croton oil (89.0 ± 1.3% by the lipid fraction with an IC 50 of 3.97 mg/ear and 57.0 ± 1.3% by the aqueous fraction with an IC 50 of 3.5 mg/ear) and arachidonic acid (42.0 ± 2.0% with an IC 50 of 4.98 mg/ear and 31.0 ± 2.0% with an IC 50 of 4.72 mg/ear). Phospholipase A 2 , purified from Apis mellifera bee venom, was also inhibited by the extract (5.0 mg/ml lipid and aqueous fraction) in vitro in a dose-dependent manner (85% by the lipid fraction with an IC 50 of 3.22 mg/ml and 25% by the aqueous fraction with an IC 50 of 3.43 mg/ ml). The methanol-water extract of I. imperati (1000 mg/kg) administered by the oral route also inhibited the formation of cotton pelletinduced granulomas (73.2 ± 1.2% by the lipid fraction and 56.14 ± 2.7% by the aqueous fraction) and did not cause gastric mucosal lesions. I. imperati extracts (10 mg/ml) also inhibited in a dosedependent manner the muscle contractions of guinea pig ileum induced by acetylcholine and histamine (IC 50 of 1.60 mg/ml for the lipid fraction and 4.12 mg/ml for the aqueous fraction). These results suggest the use of I. imperati as an anti-inflammatory and antispasmodic agent in traditional medicine. Correspondence

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“…Gaertn. displayed anti-inflammatory, analgesic, antinociceptive, antipyretic and insecticidal properties (Abad et al 1996;Forestieri et al 1996;Rathi and Gopalakrishnan 2006;Woode et al 2009). Bhogaonkar (2011) mentioned that S. nodiflora (L.) Gaertn.…”

Section: Dose Mortality Effectsmentioning

confidence: 99%

Potentiation of Synedrella nodiflora L. For Insecticidal Activity, Insect Repellency and Brine Shrimp Lethality in the Laboratory Conditions

Abdullah

Islam

2014

J Life Earth Sci

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Abstract:The insecticidal activity, insect repellency and brine shrimp lethality tests of three solvent extracts of Synedrella nodiflora L. were assessed against the adults of Tribolium castaneum (Herbst) under laboratory conditions. The methanol extract found most effective (LD 50 1.229, 0.823 and 0.569mg cm -2 for 24, 36 and 48h of exposure respectively) followed by the chloroform extract (LD 50 3.042, 2.773, 2.456 and 2.233mg cm -2 for 12, 24, 36 and 48h of exposure respectively) and petroleum ether extract (LD 50 8.416, 4.764, 3.677, 3.392 and 3.177mg cm -2 for 12, 24, 36, 48 and 60h exposure respectively). The CHCl 3 and MeOH extracts showed repellent activity against T. castaneum adults at P<0.05 and P<0.01 levels of significance, while the Pet. E. extract did not show any repellency. The similar extracts responded through brine shrimp lethality assay and the Pet. E. extract found most effective (LC 50 321.182, 248.151, 182.196 and 140.866ppm)

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Antiinflammatory activity of some medicinal plant extracts from Venezuela

Cited by 52 publications

References 4 publications

Antimicrobial and anti-inflammatory properties ofFuntumia elastica

Antimicrobial and anti-inflammatory properties ofFuntumia elastica

Anti-inflammatory and antispasmodic activity of Ipomoea imperati (Vahl) Griseb (Convolvulaceae)

Potentiation of Synedrella nodiflora L. For Insecticidal Activity, Insect Repellency and Brine Shrimp Lethality in the Laboratory Conditions

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