Antiinflammatory and Antipyretic Activities of Spartidienedione Isolated from Psila spartioides

Antipyretic, hypothermic and antiinflammatory activities and metabolites fromSolanum ligustrinum Lood.

“…The antipyretic activity of sodium naproxen is doserelated and in our experiments the maximum effect at both time intervals (0-90 min: 51% and 90-180 min: 81.1%) was reached at a dose of 25 mg/kg (Delporte et al, 1996). The antiinflammatory response to sodium naproxen is also a dose-related effect, with a maximum effect at 4.0 mg/kg of 54.6% (Backhouse et al, 1994) ( Tables 2 and 3).…”

“…The experiment was carried out in this way, since active principles with fast absorption and elimination could be present in the sample being studied, showing an effect only in the first 90 min of the assay. However, the active principles could have a slow absorption and the effect would only be seen after a 90-180 min interval (Delporte et al, 1996). The mean areas were calculated using a computer program developed in our laboratory for this purpose.…”

Natural sesquiterpenoids

“…84 The antiinflammatory and antipyretic activities of the sesquiterpene spartidienedione have been studied. 352 Dimeric sesquiterpene thioalkaloids have been shown to have potent immunosuppressive properties. 353 An HPLC method for the separation of bilobalide and ginkgolides has been described.…”

Conferin, potent antioxidant and anti-inflammatory isoflavone fromCaragana confertaBenth

“…Inflammation is a defensive reaction to injury 14 . The symptoms of inflammation (redness, edema, heat, pain, and disturbed tissue function) are the result of a complex pathophysiological process 15 .…”