Antimicrobial Activities of African Medicinal Spices and Vegetables

Tamokou, Jean-De-Dieu; Mbaveng, Armelle T.; Kuete, Victor

doi:10.1016/b978-0-12-809286-6.00008-x

Cited by 149 publications

(133 citation statements)

References 118 publications

Supporting

Mentioning

130

Contrasting

Unclassified

Order By: Relevance

“…According to established criteria, MIC values in the range of 100-1000 µg/ml are indications that botanicals have antimicrobial activities (Simoes et al, 2009 (Tamokou et al, 2017).…”

Section: Differences In the Extraction Yields Were Noted Betweenmentioning

confidence: 99%

Chemical composition and antimicrobial activity of essential oils from Aframomum citratum, Aframomum daniellii, Piper capense and Monodora myristica

Dongmo¹,

Tamokou²,

Njateng³

et al. 2019

J. Med. Plants Res.

View full text Add to dashboard Cite

This study was initiated to evaluate the chemical composition and in vitro antimicrobial activity of essential oils from four Cameroonian spices and to determine the therapeutic effect of a cream based on essential oil from Aframomum citratum. Essential oils were extracted from seeds by hydrodistillation and analyzed by gas chromatography coupled with mass spectrometry (GC/MS). The broth microdilution method w as used for the minimum inhibitory concentration ( MIC) and minimum microbicidal concentration (MMC) determinations. The therapeutic effect of a cosmetic cream based on essential oil from A. citratum seed (1.25, 2.5 and 5% w/w) was evaluated against dermatosis induced with a Methicillin-Resistant Staphylococcus aureus (MRSA) in rats. The main identified compounds in the essential oils are geraniol for A. citratum; eucalyptol, α-terpineol and geraniol for Aframomum daniellii; β-pinene, germacrene D, trans-β-caryophyllene, α-pinene, naphthalene and sabinene for Piper capense; α-phellandrene, germacradienol and δ-cadinene for Monodora myristica. Essential oil of A. citratum (MIC = 8-4096 µg/ml) was the most active against bacteria and fungi, following in decreasing order by those of A. daniellii, P. capense and M. myristica. The antibacterial activity of the essential oil of A. citratum against MRSA and Escherichia coli S2(1) (MIC = 8 µg/ml) was higher than that of amoxicillin used as reference drug (MIC = 128-256 µg/ml). The combination of essential oils of A. citratum and A. daniellii (1:1) displayed a synergistic effect. The cream based on essential oil of A. citratum (5%) and Baneocin (reference drug) eradicated the dermatosis induced with MRSA in rat after two weeks of treatment. These results indicate that the tested essential oils possess antimicrobial activities which could be a function of either the individual or the additive effects of the identified phytoconstituents.

show abstract

“…According to established criteria, MIC values in the range of 100-1000 µg/ml are indications that botanicals have antimicrobial activities (Simoes et al, 2009 (Tamokou et al, 2017).…”

Section: Differences In the Extraction Yields Were Noted Betweenmentioning

confidence: 99%

Chemical composition and antimicrobial activity of essential oils from Aframomum citratum, Aframomum daniellii, Piper capense and Monodora myristica

Dongmo¹,

Tamokou²,

Njateng³

et al. 2019

J. Med. Plants Res.

View full text Add to dashboard Cite

show abstract

“…Phenols are secondary metabolites that are prepared by plants as a defense mechanism to protect themselves against parasitic organisms (Tamokou, Mbaveng, & Kuete, ). From the results obtained in this study, S. angustifolia had the highest total phenolic content of 59.93 ± 0.05 mg GE/g DW, while A. mysorensis had a total phenolic content of 26.5 ± 1.67 mg GE/g DW, respectively.…”

Section: Resultsmentioning

confidence: 99%

“…Plant‐derived therapeutic compounds belong to various classes of secondary metabolites that have a wide range of activity which is dependent on the species, climate of the country of origin, the topography and may contain different categories of active components (Tamokou et al, ). The GC‐MS chromatogram of S. angustofolia and A. mysorensis confirmed the presence of several components belonging to different classes of compounds as depicted in Tables and above, respectively.…”

Section: Resultsmentioning

confidence: 99%

“…Plant-derived therapeutic compounds belong to various classes of secondary metabolites that have a wide range of activity which is dependent on the species, climate of the country of origin, the topography and may contain different categories of active components (Tamokou et al, 2017 (Itoh et al, 2018). Hexanoic acid is a short natural monocarboxylic acid present in some fruits and plants reported to be an effective treatment against several pathogens in tomato plants (Llorens, Camanes, Lapena, & Garca-Agustin, 2016).…”

Section: Gc-ms Profilementioning

confidence: 99%

See 1 more Smart Citation

Evaluation of nutritional value ofAsystasia mysorensisandSesamum angustifoliaand their potential contribution to human health

Maina

Madivoli

Ouma

et al. 2019

Food Science & Nutrition

View full text Add to dashboard Cite

Wild indigenous vegetables make considerable contributions to food baskets among subsistence farmers in sub‐Saharan Africa. The aim of this study was to evaluate the proximate analysis, mineral composition, vitamin C content, β‐carotene content, and GC‐MS profile of crude methanolic extracts of Asystasia mysorensis and Sesamum angustifolia . Crude extracts obtained through sequential extraction using ethyl acetate and methanol were screened for the presence of secondary metabolites. Functional groups present were determined with a Shimadzu FT‐IR spectrophotometer, while β‐carotene content and ascorbic acid content were evaluated using a Shimadzu HPLC and Shimadzu UV‐VIS spectrophotometer, respectively. Secondary metabolites present in the extracts were determined qualitatively using a Shimadzu GC‐MS system equipped with a NIST spectral database. From the results obtained, the two plants could supply the recommended daily requirement for micronutrient and vitamin C content needed for a healthy diet. The total phenolic and flavonoid contents in S. amgustifolia were higher as compared to A. myorensis; hence, their consumption is highly beneficial as some compounds identified in the GC‐MS profile have been reported to have medicinal properties. The findings on the mineral and chemical composition, GC‐MS profile of A. mysorensis and S. angustifolia indicate that their consumption may provide the recommended nutritional requirements needed for a healthy diet.

show abstract

“…Zingiberaceae commonly known as ginger is an aromatic plant, perennial herbs consisting of more than 1,300 species and 52 genera with the tuberous rhizomes and creeping horizontal, distributed from tropical Asia, Africa and America [1]. Among them, the distribution of ginger predominantly was found in tropical Asia with approximately about 1000 species occur in this area.…”

Section: Introductionmentioning

confidence: 99%

Distribution and Phytocomponent in the Ethanol Extract of Globba candida Gagnep. (Zingiberaceae) by GC-MS Analysis

Andila

Tirta²

2019

JTLS

View full text Add to dashboard Cite

Globba is the third largest genera in the Zingiberaceae family, distributed in tropical and subtropical regions with the center of biodiversity in Southeast Asia. The study about phytochemical contents Globba is an interesting especially Globba candida Gapnep which have been never reported. The aims of this study were to observe distribution and phytochemical compounds of ethanol extract of G. candida Gapnep. found on Bali Island. Hydrodistillation was used to determine the presence of its essential oil and a Gas Chromatography-Mass Spectrometry (GC-MS) was used to carry out the phytochemical analysis of the essential oil and ethanol extracts of G. candida Gapne. The phytochemical analysis of the rhizomes and leaves ethanol extracts of G. candida Gapnep revealed 36 and 8 identified chemical compounds representing 85,82% and 85,47% of the total analyzed extracts. However, there was no essential oil constituent found in G. candida Gapnep. The main compounds of the rhizome extract of G. candida Gapnep were levoglucosan 19.07%, allylhydrazone acetaldehyde 5.52%, trans-2,3-epoxybutane 6.30%, butan-3-enoic acid methyl ester 4.36%, 2-methylcyclopentanone 4.02%, and 2-n-propyl-oxetan 4.00%. While the dominant contents of the leaves extract of G. candida Gapnep were pinostrobin chalcone 75.63%.

show abstract

Antimicrobial Activities of African Medicinal Spices and Vegetables

Cited by 149 publications

References 118 publications

Chemical composition and antimicrobial activity of essential oils from Aframomum citratum, Aframomum daniellii, Piper capense and Monodora myristica

Chemical composition and antimicrobial activity of essential oils from Aframomum citratum, Aframomum daniellii, Piper capense and Monodora myristica

Evaluation of nutritional value ofAsystasia mysorensisandSesamum angustifoliaand their potential contribution to human health

Distribution and Phytocomponent in the Ethanol Extract of Globba candida Gagnep. (Zingiberaceae) by GC-MS Analysis

Contact Info

Product

Resources

About