Antimicrobial activity of a polyherbal formulation Ambrex

Biological Properties of Polyherbal Formulations: A Review of their Antimicrobial, Anti-Inflammatory, Antioxidant, and Toxicological Activities

“…31 Various polyherbal medicines have been found to exhibit high antimicrobial activity due to the presence of alkaloids, phenols, glycosides, saponins, flavonoids, tannins, salicylic acid, and terpenes. 4,17,[32][33][34] Tannins, for instance, are water-soluble polyphenols found in many plant foods and have been recognized as effective antibacterial agents against various pathogens. They have been reported to prevent the growth of microorganisms (fungi, yeasts, bacteria, and viruses) by precipitating microbial protein.…”

“…This indicates that these herbal remedies meet the criteria proposed by Cos et al (2006), which consider extracts with a selective activity and MIC values below 1-50 µg/mL as noteworthy. Also, polyherbal remedies such as Ambrex (8.7-23.4 μg/mL), 4 Ya-Sa-Marn-Phlae (4-32 µg/mL) 20 , and KWTa, KWTb, KWTc, HBfs, HBts, AL, and FB (≤ 25 µg/mL) 39 had antimicrobial activities lower than 50 µg/mL, hence, they possess strong antimicrobial activity.…”

“…3 When monotherapy is inadequate to combat a clinical condition, traditional medicine employs polyherbal approaches. 4 Polyherbal medicines, which contain two or more herbal ingredients are often more effective than single drugs because of their complementary and/ or potentiating activities. The combination of two or more herbal extracts brings about increased therapeutic efficiency, enhanced pharmacological actions, faster relief, and reduced adverse effects as compared to conventional medicine due to a lower dose of administration.…”

“…The combination of two or more herbal extracts brings about increased therapeutic efficiency, enhanced pharmacological actions, faster relief, and reduced adverse effects as compared to conventional medicine due to a lower dose of administration. 1,2,4,5 Polyherbal medicines are now widely preferred and used around the world because of their high effectiveness, ready availability, low toxicity, and environmentally friendly nature, and it reduces the time of treatment or the individual cost of anti-inflammatory and antimicrobial drugs, resulting in lower prescription costs. 3,5 The concept of polyherbal combination has been well established and has achieved remarkable success in allopathic medicine, providing patients with new hope.…”