Antimicrobial activity of biopolymeric thin films containing flavonoid natural compounds and silver nanoparticles fabricated by MAPLE: A comparative study

Cristescu, R.; Visan, Anita Ioana; Socol, G.; Surdu, Vasile–Adrian; Oprea, Alexandra Elena; Grumezescu, Valentina; Chifiriuc, Mariana Carmen; Boehm, Ryan D.; Yamaleyeva, Dina; Taylor, Michael S.; Narayan, Roger J.; Chrisey, Douglas B.

doi:10.1016/j.apsusc.2015.11.252

Cited by 24 publications

(19 citation statements)

References 25 publications

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“…In both hospitals and community-acquired infections, the antimicrobial resistance has reached a crisis point, since it became an affecting public health factor throughout the world [1]. The microbial resistance to antibiotics is referred to the fact that the majority of these antibiotics are targeting intercellular components without any effect on the cellular morphology.…”

Section: Introductionmentioning

confidence: 99%

Assessment of in situ-Prepared Polyvinylpyrrolidone-Silver Nanocomposite for Antimicrobial Applications

et al. 2017

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Polyvinylpyrrolidone (PVP) is employed in several potential applications, relying of its special chemical and physical properties in addition to its low toxicity and biocompatibility. The aim of this work is to prepare polyvinylpyrrolidone-silver (PVP-Ag) nanocomposite with high inhibiting effect on the microbial growth and low cytotoxicity. In situ prepared small stable spherical silver nanoparticles, with narrow range particle size distribution, were obtained by easy, economical and rapid chemical reduction method. Silver ions were reduced to silver nanoparticles using low amount of sodium borohydride (NaBH4) as a strong reducing agent. PVP-Ag nanocomposite was prepared using PVP as a stabilizing and capping agent. Formation of the spherical silver nanoparticles with mean particle size 5 nm was confirmed by ultraviolet-visible spectroscopy, high resolution transmission electron microscopy, and dynamic light scattering. The inhibiting growth effect of the nanocomposite toward Gram-positive bacteria (Staphylococcus aureus), Gram-negative bacteria (Pseudomonas aeruginosa), and yeast fungus (Candida albicans) were studied. The cytotoxicity of the nanocomposite against BJ1 normal skin fibroblast cell line was tested. Results of this work presented perfect antimicrobial activity of the PVP-Ag nanocomposite towards bacteria and fungi with low cytotoxicity, which may lead to promising applications in skin wound healing.

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Section: Introductionmentioning

confidence: 99%

Assessment of in situ-Prepared Polyvinylpyrrolidone-Silver Nanocomposite for Antimicrobial Applications

et al. 2017

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“…The antimicrobial effects of edible and coating films with essential oils have been screened against a wide range of microorganisms over the years. Several researchers have proposed that the antimicrobial action of essential oils may be attributed to their ability to penetrate through bacterial membranes to their interior of the cell and exhibit inhibitory activity on the functional properties of the cell, and to their liphophilic properties (Cristescu et al, 2016;Calo et al, 2015;Cheng et al, 2015;Oliveira et al, 2015;Atar es & Chiralt, 2016;Tawakkal et al, 2016).…”

Section: Antimicrobial Filmsmentioning

confidence: 99%

Biopolymer films and the effects of added lipids, nanoparticles and antimicrobials on their mechanical and barrier properties: a review

Castro-Rosas

Cruz-Gálvez

Aldapa

et al. 2016

Int J of Food Sci Tech

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Summary Packaging made from biodegradable biopolymers such as proteins, polysaccharides and lipids is a promising alternative to synthetic polymers. Films made from these biopolymers exhibit certain disadvantages in terms of their mechanical, barrier and physicochemical properties. Plasticisers, nanoparticles, lipids and antimicrobial compounds can be added to them to improve these properties. The tendency of biopolymer films to brittleness can be mitigated by adding plasticisers and/or nanoparticles. These films also tend to have high water vapour permeability, which can be reduced by adding lipids and/or nanoparticles. Incorporating natural compounds with antimicrobial activity into biopolymer films can provide them the advantages of maintaining food safety and extending shelf life. Addition of plasticisers, nanoparticles, lipids and/or antimicrobial compounds to biopolymer films can help to make them comparable to conventional synthetic films with the advantages that they reduce pollution and are biodegradable.

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“…Further, considerable attention has been focused on development and utilization of secondary metabolites of plants (phytochemicals) as a substitute to and/or in combination with traditional antibiotics for treating infections. Between the phytochemicals, flavonoids are perfect candidates because they are extensively distributed in edible plants and possess broad pharmacologic activity [66]. Flavonoids are a group of heterocyclic organic compounds frequently found in vegetables, fruit, flowers, nuts, wine, seeds, stems, tea, honey and propolis [66].…”

Section: The Literature Survey Of Renewable Materials-based Compositementioning

confidence: 99%

“…Between the phytochemicals, flavonoids are perfect candidates because they are extensively distributed in edible plants and possess broad pharmacologic activity [66]. Flavonoids are a group of heterocyclic organic compounds frequently found in vegetables, fruit, flowers, nuts, wine, seeds, stems, tea, honey and propolis [66]. Composite thin films of biopolymer (polyvinylpyrrolidone), flavonoid (quercetin dihydrate and resveratrol)-biopolymer and silver nanoparticles biopolymer were deposited using MAPLE method demonstrating the anti-inflammatory, antispasmodic, anti-allergic and antimicrobial properties obtained effects [66].…”

Section: The Literature Survey Of Renewable Materials-based Compositementioning

confidence: 99%

Composite Coatings Based on Renewable Resources Synthesized by Advanced Laser Techniques

Visan¹,

Ristoscu²,

Mihăilescu³

2016

Composites From Renewable and Sustainable Materials

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This chapter reviews the progress and perspectives of composite materials in the form of thin films based on renewable resources for biofabrication of a new generation of medical implants with antibacterial properties. The chapter starts with an overview of the types of renewable materials that were currently studied and of the unique properties which make them perfect candidates for numerous bio-related applications. A briefing of recent progresses in the field of advanced laser synthesis of composites from renewable and sustainable materials, as well as the relevant results in our researches is made. The discussion spans composite coatings based on renewable resources, [e.g., chitosan (CHT) and lignin (Lig)] as biomaterials intended for metallic implants. A particular attention is given to lignin synthesis in the form of thin films due to its ability to functionalize the medical implant surface while preserving the similar composition and the structural properties of the raw, renewable biomaterial. We focused on recent technological advancements (e.g., matrix-assisted pulsed laser evaporation (MAPLE) and Combinatorial-MAPLE) which have brought the spotlight onto renewable biomaterials, by detailing the relevant engineering data of processing. This chapter concludes that the extensions of advanced laser techniques are viable fabrication methods of a new generation of metallic implants.

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Antimicrobial activity of biopolymeric thin films containing flavonoid natural compounds and silver nanoparticles fabricated by MAPLE: A comparative study

Cited by 24 publications

References 25 publications

Assessment of in situ-Prepared Polyvinylpyrrolidone-Silver Nanocomposite for Antimicrobial Applications

Assessment of in situ-Prepared Polyvinylpyrrolidone-Silver Nanocomposite for Antimicrobial Applications

Biopolymer films and the effects of added lipids, nanoparticles and antimicrobials on their mechanical and barrier properties: a review

Composite Coatings Based on Renewable Resources Synthesized by Advanced Laser Techniques

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