Antimicrobial activity of essential oil and methanol extracts of Achillea sintenisii Hub. Mor. (Asteraceae)

Abstract

The essential oil, obtained by Clevenger distillation, and water-soluble and water-insoluble parts of the methanol extracts of Achillea sintenisii Hub. Mor. were individually assayed for their antimicrobial activities against 12 bacteria and two yeasts, Candida albicans and C. krusei. No activity was exhibited by the water-soluble subfraction, whereas both the water-insoluble subfraction of the methanol extracts and the essential oil were found to be active against some test microorganisms studied. Since the essential oil possessed stronger activity than the other extracts tested, it was further fractionated and the fractions were evaluated for their antimicrobial activity, followed by GC-MS analysis, resulting in the identification of 32 compounds which constituted 90.2% of the total oil. The GC-MS analysis of the oil and its fractions revealed that the main components of the oil, e.g. camphor and eucalyptol, possessed appreciable activity against C. albicans and Clostridium perfringens. The fi ndings presented here also suggest that the other constituents of the oil, e.g. borneol and piperitone can also be taken into account for the activity observed.

Chemical composition of the essential oils and extracts of Achillea species and their biological activities: A review

“…fumigatus (Bezic et al, 2003;Bekhechi et al, 2011;Falconieri et al, 2011), A. niger (Bezic et al, 2003;Ristic et al, 2004;Stojanovic et al, 2005;Falconieri et al, 2011), C. albicans (Barel et al, 1991;Magiatis et al, 2002;Unlu et al, 2002;Bezic et al, 2003;Candan et al, 2003;Sokmen et al, 2003;El-Shazly et al, 2004;Sokmen et al, 2004;Stojanovic et al, 2005;Tuberoso et al, 2005;Iscan et al, 2006;Bader et al, 2007;Karamenderes et al, 2007;Maggi et al, 2009;Turkoglu et al, 2010;Falconieri et al, 2011;Kucukbay et al, 2011;Radulovic et al, 2012;Albayrak, 2013;Kazemi and Rostami, 2015;Turkmenoglu et al, 2015;Fahed et al, 2016), C. glabrata (Magiatis et al, 2002;Al-Snafi, 2013), C. krusei (Candan et al, 2003;Sokmen et al, 2003;Falconieri et al, 2011;Turkmenoglu et al, 2015), C. herbarum (Bekhechi et al, 2011), C. kefyr (Ghasemi et al, 2008), C. krusei (Candan et al, 2003;Sokmen et al, 2003;Falconieri et al, 2011;Turkmeno...…”

Variation in Chemical Composition and Antibacterial Activities of Essential Oils from Two Species of Houttuynia THUNB.

“…16) Caryophyllene and bornyl acetate have been claimed to also contain the antibacterial. [17][18][19][20] The a-pinene, b-pinene and limonene had a strong antibacterial activity [21][22][23][24] and exerted their toxic effects against these microorganisms through the disruption of bacteria or fungal membrane integrity [25][26][27] and the inhibition of respiration and ion transport processes. They also increased the membrane permeability in yeast cells and isolated mitochondria.…”

Antioxidant and antimicrobial activities of essential oil and extracts of fennel (Foeniculum vulgare Mill.) seeds from Pakistan

“…[1,2] Food-borne diseases are a severe health problem in the world, even in well-developed nations. [3] The consumption of food contaminated with food-borne microorganisms can pose a serious threat to human health. The existence of microorganisms causes spoilage and results in reduction of the quality and quantity of processed foods.…”