Antimicrobial Activity of Essential Oils: A 1976-1986 Literature Review. Aspects of the Test Methods

Janssen, A. M.; Scheffer, J. J. C.; Svendsen, A. Baerheim

doi:10.1055/s-2006-962755

Cited by 450 publications

(283 citation statements)

References 8 publications

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“…Our finding of a significant antifungal activity of essential oil against C. albicans and C. parapsilosis (MIC values ranging from 0.125 to 0.312%) is therefore of clinical relevance. Also in Table 3, it is shown the results of standard antibiotics, that it was added only to assess the susceptibility of tested strains, whereas a comparison of the antimicrobial activity of essential oils and antibiotics cannot be made from this manner (Janssen et al, 1987;Kalemba & Kunicka, 2003), since was described above, the essential oil of H. brasiliense it is a complex mixture of compounds, like all essential oils, where the active principle can be in small proportion. Also we stand out that it is not pretension of this study to compare the results with antibiotics used in the clinic, but that they can serve to add value if the cited essential oil as an ingredient of a pharmaceutical formulation.…”

Section: Resultsmentioning

confidence: 99%

Chemical composition and antimicrobial activity of Hedyosmum brasiliense Miq., Chloranthaceae, essential oil

Kirchner

Wisniewski

Cruz

et al. 2010

Rev. bras. farmacogn.

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RESUMO:Óleo essencial de Hedyosmum brasiliense Miq., Chloranthaceae: composição e atividade antimicrobiana. Hedyosmum brasiliense Miq., Chloranthaceae, é uma espécie endêmica no Brasil, conhecida como "cidrão". Embora H. brasiliense seja utilizada como calmante na medicina popular, não foi ainda caracterizada quanto aos constituintes químicos. Este trabalho apresenta a composição do óleo essencial, obtido pela destilação de folhas frescas e de amostra de óleo essencial armazenada por três meses, analisadas por GC-FID e CG-MS. Os efeitos inibitórios do óleo essencial foram testados pelo método da diluição em agar, contra seis espécies de bactérias (Bacillus subtilis, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus aureus e S. saprophyticus). Adicionalmente, seis espécies de fungos (Candida albicans, C. parapsilosis, Microsporum canis, M. gypseum, Trichophyton rubrum e T. mentagrophytes) foram incluídas. Dentre os principais constituintes, α-terpineol (10,2%), curzereno (8,9%), pinocarvona (8,4%) e β-tujeno (7,1%) foram os encontrados em maior quantidade. O óleo essencial apresentou baixa atividade contra microorganismos Gram-negativos. Entretanto, a atividade é extraordinária contra bactérias Gram-positivas e fungos, com valores de MIC entre 0,125 a 2,5% (v/v). Unitermos:Hedyosmum brasiliense, Chloranthaceae, óleo essencial, atividade antimicrobiana. ABSTRACT:Hedyosmum brasiliense Miq., Chloranthaceae, is an endemic species of Brazil, locally known as "cidrão". Although H. brasiliense is popularly used as sedative, chemical constituents of this species remains uncharacterized. This work presents the essential oil composition, obtained by the distillation of fresh leaves and a sample stored for three months, analysed by GC-FID and GC-MS. The inhibitory effects of the essential oil were tested by the agar dilution method against six bacterial species (Bacillus subtilis, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus aureus and S. saprophyticus). In addition, six fungal species (Candida albicans, C. parapsilosis, Microsporum canis, M. gypseum, Trichophyton rubrum and T. mentagrophytes) were included. Among the determined constituents, α-terpineol (10.2%), curzerene (8.9%), pinocarvone (8.4%) and β-thujene (7.1%) were found as the main components. The essential oil has low activity only against Gram-negative microorganisms. However, it is a remarkable active against Grampositive bacteria and fungi with MIC values ranging from 0.125 to 2.5% (v/v).

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Section: Resultsmentioning

confidence: 99%

Chemical composition and antimicrobial activity of Hedyosmum brasiliense Miq., Chloranthaceae, essential oil

Kirchner

Wisniewski

Cruz

et al. 2010

Rev. bras. farmacogn.

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“…A comparação de dados obtidos com óleos e extratos deve ser analisada levando-se em consideração que a composição dos mesmos varia em função das condições climáticas e ambientais (Janssen et al, 1987;Sivropoulou et al, 1995;Tavares et al, 2005;Franco et al, 2005;Potzernheim et al, 2006;Carvalho-Filho et al, 2006). Além disto, o método a ser utilizado para determinar a atividade antimicrobiana e a seleção de linhagens pode infl uenciar o resultado obtido (Janssen et al, 1987;Nascimento et al, 2007), sendo o método de difusão em disco uma técnica bastante recomendada para avaliação de óleos (Morris et al, 1979;SmithPalmer et al,1998).…”

Section: Resultsunclassified

Avaliação da atividade antibacteriana de folhas de Myrtus communis L. (Myrtaceae)

Salvagnini¹,

Oliveira²,

Santos³

et al. 2008

Rev. bras. farmacogn.

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Section: Resultsmentioning

confidence: 99%

“…Many factors vary between assays which include differences in microbial growth, exposure of microorganisms to plant oils, the solubility of oils or oil components, the use and quantity of emulsifier and others elements. 14,20,21 In the agar diffusion method, the hydrophobic nature of the majority of essential oil components hamper the uniform diffusion of these substances through the agar medium that may account for differences on the results obtained.The antimicrobial properties of the oil are supposed to be associated to the high hydrocarbon monoterpene content, especially to its majority component, α-pinene. The antimicrobial activity of this compound was related to its capacity of destruction of cellular integrity, inhibition of respiration and ion transportation process and to increase membrane permeability of yeast cells.…”

mentioning

confidence: 99%

Seasonal variation and antimicrobial activity of Myrcia myrtifolia essential oils

Cerqueira¹,

Souza-Neta²,

Passos³

et al. 2007

J. Braz. Chem. Soc.

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Os óleos essenciais das folhas, flores e frutos de Myrcia myrtifolia DC foram coletados ao longo dos anos de 2002 e 2003 e foram analisados utilizando CG-DIC e CG-EM. No total foram identificados 28 componentes sendo que o α-pineno foi a substância predominante em todas as amostras analisadas apresentando-se em concentrações que variaram entre 61.5 e 90.9%. As propriedades antimicrobianas do óleo essencial das folhas coletadas em outubro de 2002 foram avaliadas contra seis bactérias, duas leveduras e cinco fungos filamentosos sendo mais fortemente ativo contra Microsporum canis e Trichophyton rubrum, ativo contra Staphylococcus aureus, Staphylococcus aureus resistente à meticilina, Candida albicans, Cryptococcus neoformans e Aspergillus fumigatus. O óleo ainda mostrou uma toxicidade moderada, LC 50 of 479,16 μg mL -1 , contra Artemia salina.This work reports the seasonal variation of the composition of leaf volatile oils and the composition of volatile oils from flowers and fruits of Myrcia myrtifolia DC harvested in the sand dunes of Salvador, Bahia, northeastern region of Brazil between 2002 and 2003. The oils were analyzed by GC-FID and GC-MS so that 28 components were identified. α-Pinene was predominant in a range from 61.5 to 90.9% in all samples analyzed. The leaf oil collected in October 2002 had their antimicrobial properties tested against six bacteria, two yeasts and five filamentous fungi being active against Staphylococcus aureus, methicilin-resistant Staphylococcus aureus, Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus, and showed strongest activity against Microsporum canis and Trichophyton rubrum. The oil displayed moderate toxicity against Artemia salina showing a LC 50 of 479.16 μg mL -1 .Keywords: Myrtaceae, Myrcia myrtifolia, essential oil, monoterpene, sesquiterpene, antimicrobial activity IntroductionAromatic plants have been used since ancient times as antiseptics and anti-infectious agents, as aroma in perfumes and cosmetics as well as preservative and flavour ingredients in food and beverages. Their biological properties are directly related with their chemical compositions, which can be affected by environmental, geographical, seasonal and circadian variations.The family Myrtaceae is constituted by 140 genera with about 3000 species, which are widely distributed in America and Australia. 1 The genus Myrcia comprises more than 300 species that grow in all Brazilian territory. Indigenous tribes and traditional Brazilian communities have used several species of this genus as astringent, against diabetes and diarrhea, as diuretic, to stanch hemorrhages, against the hypertension and ulcers of the mouth. 2 Some works were published regarding the chemistry and the biological properties of Myrcia species. From M. citriofolia, the occurrence of a C-methylated flavone, eucalyptin, was related, 3 from the methanolic extract of M. multiflora were isolated flavonol, flavanone and acetophenone glucosides along with myricitrin, mearnssitin, quercitrin, desmanthin-1 and guaijaverin...

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Antimicrobial Activity of Essential Oils: A 1976-1986 Literature Review. Aspects of the Test Methods

Cited by 450 publications

References 8 publications

Chemical composition and antimicrobial activity of Hedyosmum brasiliense Miq., Chloranthaceae, essential oil

Chemical composition and antimicrobial activity of Hedyosmum brasiliense Miq., Chloranthaceae, essential oil

Avaliação da atividade antibacteriana de folhas de Myrtus communis L. (Myrtaceae)

Seasonal variation and antimicrobial activity of Myrcia myrtifolia essential oils

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