In this study, the antimicrobial activity of P. peruviana was investigated. The antimicrobial activity was evaluated according to the microdilution method by using B. megaterium, P. aeruginosa, E. coli, K. pneumoniae, P. vulgaris, E. aeregenes, C. albicans, C. globrata, C. tropicalis, Trichophyton sp. and Epidermaphyton sp. In the end of experimental studies, the fruit extract of P. peruviana was inhibited the growth of microorganisms used in the test at different ration. MIC values of fruit was determined as 128-1054-µg/ml.