Antimicrobial activity of flavonoids and steroids isolated from two Chromolaena species

Abstract

The crude extracts (dichloromethanic and ethanolic)

Detection of flavonoids in glandular trichomes of Chromolaena species (Eupatorieae, Asteraceae) by reversed-phase high-performance liquid chromatography

“…Both Chromolaena species presented mainly flavonol and flavone derivatives in their glands, including two glycosides (Figure 1). In this work, 12 of the 15 flavonoids originally reported in the crude extracts of the leaves of both species (Taleb-Contini et al, 2003, 2004 were characterized in their glandular trichomes (Table I), with the exception of compounds 7, 9 and 14, which were not detected in any of them. In the previous study, the crude extracts of the leaves of C. hirsuta furnished 14 flavonoids (Table I) and now nine of them were found in the glandular trichomes (Table I, Figure 2).…”

“…It is important to stress that flavonoids exhibit antioxidant, anti-inflammatory, antimicrobial, vascular activities and other medicinal properties (Xu, Lee, 2001;Ogundipe et al, 2001). Antimicrobial, antiprotozoal and antioxidant activities were observed for the flavonoids of C. hirsuta and C. squalida (Taleb-Contini et al, 2003;Taleb-Contini et al, 2004;Taleb-Contini et al, 2006).…”

“…All analyses were repeated three times. All compounds were obtained from previous investigations of C. hirsuta and C. squalida (Taleb-Contini et al, 2003, 2004 in which each species provided 14 and six flavonoids, respectively. …”

Bioactive Properties of Eremostachys macrophylla Montbr. & Auch. Rhizomes Growing in Iran

“…19 Antioxidant, cytotoxic and antibacterial effects of fatty acids, steroids were confirmed previously. [25][26][27][28][29][30][31] Likewise, some polycyclic aromatic hydrocarbons and terpenoids have been reported for these bioactive properties. [32][33][34][35] Therefore, the potential biological efficacy of DCM extract may be related to the combination of these compounds and their synergies correlation with each other.…”

Study on Antioxidant and Cytotoxic Properties of Olea Dioica Roxb. Crude Extract and Its Pure Compound Collected From Western Ghats, Karnataka, India.

“…Secondary metabolites such as flavonoids [12], terpenoids [13], steroids [14], saponins [15], glycosides [16], and phenols have the pharmacological properties which are extracted from higher plants.…”