Antimicrobial Activity of Geranium Oil against Clinical Strains of Staphylococcus aureus

S u m m a r yIntroduction: Staphylococcus aureus is an important etiological agent of skin and soft tissue infections. Due to the increasing resistance of this bacterium to antimicrobial agents, treatment of staphylococcal infections remains a great challenge for clinicians and requires an alternative treatment options. Objective: The aim of the study was to determine the antimicrobial activity of essential oils: caraway (CEO), patchouli (PEO) and geranium (GEO) against S. aureus strains isolated from skin lesions in the course of staphylococcal skin infections. Methods: The antibacterial activity of essential oils was tested using the dilution method in Mueller-Hinton broth. Results: The antimicrobial effect of CEO, PEO and GEO was observed. The highest antimicrobial activity showed PEO (MIC = 1.7±0.8 μl/ml), the lower was observed for GEO (MIC = 5.4±2.0 μl/ml) and CEO (MIC = 18.8±10.3 μl/ml). Conclusion: All tested essential oils showed antibacterial activity against S. aureus strains isolated from skin lesions of patients with staphylococcal skin infections. Application of the CEO, PEO and GEO can become an alternative method of treatment of staphylococcal infections, but further microbiological tests and clinical trials should be assessed. key words: Staphylococcus aureus, caraway oil, patchouli oil, geranium oil, staphylococcal skin infections

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“…The antimicrobial activity of GEO against clinical isolates of S. aureus was considered in details by Bigos et al [27].…”

Section: Resultsmentioning

confidence: 99%

Experimental Paper. Activity of essential oils against Staphylococcus aureus strains isolated from skin lesions in the course of staphylococcal skin infections

Kwiatkowski

Mnichowska-Polanowska

Pruss

et al. 2017

Herba Polonica

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“…is little known for its antibacterial activity or relevant properties. Several studies have demonstrated that essential oils isolated from Geranium macrorrhizum and Pelargonium graveolens (family Geraniaceae) have high antimicrobial potential against of Bacillus subtilis, Pseudomonas aeruginosa, and S. aureus strains [1,7]. A recent South Korean study (PJ907105) demonstrated that a G. koreanum Kom.…”

Section: Discussionmentioning

confidence: 99%

Antibacterial activities of bark extracts from Fraxinus rhynchophylla Hance and Geranium koreanum Kom. against clinical strains of Clostridium perfringens in chickens

Oh¹,

Lee²,

Wei³

et al. 2015

Korean Journal of Veterinary Research

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: Necrotic enteritis (NE) caused by Clostridium (C.) perfringens commonly occurs in domestic broiler farms since antibiotic supplementation in poultry feed has been banned. We evaluated the antibacterial activities of medicinal plant extracts against C. perfringens isolates to select alternative compounds for preventing NE. We compared antibacterial activities using two methods and evaluated susceptibilities of the isolates based on minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). Two (Fraxinus rhynchophylla Hance [FRH] and Geranium koreanum Kom.[GKK]) of the 30 plant extracts had potent antibacterial activities against C. perfringens ATCC 13124 in two assays. The MIC values for FRH and GKK against 20 C. perfringens isolates were 128~256 µg/mL and 32~128 µg/mL, respectively. The geometric MIC mean values for the two extracts were 147.2 µg/mL and 68.8 µg/mL, respectively. The MBCs for the two extracts against the same strains were 1,024~2,048 µg/mL and 256~1,024 µg/mL, respectively. The geometric mean MIC and MBC for GKK were about two-fold lower than those of FRH. The modified spot-on-lawn assay may be useful for measuring primary antibacterial potential. FRH and GKK are expected to be used as feed additives to prevent or treat NE in veterinary practice.

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“…Among 67 components of geranium oil from Pelargonium graveolens Ait, citronellol, geraniol, nerol, citronellyl formate, isomenthone and linalool are the main constituents responsible for its biological activity. The research based on agar dilution method showed that the geranium oil had very strong activity against the clinical S. aureus strains, including MRSA strains, exhibiting MIC values of 0.25-2.50 μL/mL [85]. Moreover, Rosato et al showed the occurrence of a synergism between geranium oil and norloxacin against reference S. aureus strains [86].…”

Section: Frontiers In Staphylococcus Aureus 212 Frontiers In Staphylomentioning

confidence: 99%

“…Recently research of many authors showed also the antimicrobial activity of geranium oil (GO) against MRSA [84,85]. Among 67 components of geranium oil from Pelargonium graveolens Ait, citronellol, geraniol, nerol, citronellyl formate, isomenthone and linalool are the main constituents responsible for its biological activity.…”

Section: Frontiers In Staphylococcus Aureus 212 Frontiers In Staphylomentioning

confidence: 99%

Bee Products and Essential Oils as Alternative Agents for Treatment of Infections Caused by S. aureus

Szweda¹,

Kot²

2017

Frontiers in Staphylococcus Aureus

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Bacteria of the genus Staphylococcus are important human and veterinary pathogens. A crucial characteristic for this group of bacteria is that they can easily acquire mechanisms of antibiotic resistance for a plethora of antibiotics currently in use for human and animal therapies. Therefore, there is a great need to ind novel, non-antibiotic chemotherapeutics with marked antistaphylococcal activity. Promising but still underestimated group of potential antistaphylococcal chemotherapeutics constitute bee products: honey, pollen, royal jelly, fermented pollen and especially propolis. Another group of natural products that exhibit promising antibacterial activity is essential oils. Usefulness of bee products and essential oils in the treatment of infections caused by S. aureus has been conirmed by results of many investigations carried out by researches in diferent regions of the world. In this chapter, we have presented the review of publication in this area as well as perspectives and limitations of future applications of these two groups of natural products.

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Antimicrobial Activity of Geranium Oil against Clinical Strains of Staphylococcus aureus

Cited by 50 publications

References 31 publications

Experimental Paper. Activity of essential oils against Staphylococcus aureus strains isolated from skin lesions in the course of staphylococcal skin infections

Experimental Paper. Activity of essential oils against Staphylococcus aureus strains isolated from skin lesions in the course of staphylococcal skin infections

Antibacterial activities of bark extracts from Fraxinus rhynchophylla Hance and Geranium koreanum Kom. against clinical strains of Clostridium perfringens in chickens

Bee Products and Essential Oils as Alternative Agents for Treatment of Infections Caused by S. aureus

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