Antimicrobial activity of Streblus asper leaf extract

Abstract

Bactericidal activity was found in the 50% ethanol (v/v) extract of Streblus asper leaves. The extract possessed a selective bactericidal activity towards Streptococcus, especially to Streptococcus mutans which has been shown to be strongly associated with dental caries. The extract had no effect on cultures of Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa, Staphylococcus coagulase positive, Staphylococcus coagulase negative, Serratia marcescens, Klebsiella pneumoniae, Enterobacter, Pseudomonas aeruginosa, Burkholderia pseudomeallei and Candida albicans. The minimum growth inhibitory concentration and the minimum bactericidal concentration of S. asper extract against 10(8) CFU/mL of S. mutans was 2 mg/mL. The active compound is partially polar, partially heat labile, precipitated by 80% ammonium sulphate, and possesses a molecular weight larger than 10 000 Da. The potential for using S. asper extract as a natural product for controlling dental caries is discussed.

Antibacterial Activity of Volatile Oil of Ixora Cocciniea Against Burn Isolates.

“…The MIC values for the volatile oil of Ixora Cocciniea were shown in table-2. Among the five burnt bacterial isolates, the MIC of volatile oil of Ixora Cocciniea observed at E.coli by the minimum zone of inhibition (Wongkham et al, 2001). …”

Anticariogenic Activity and Haemolytic Study of Some Medicinal Plants Leaf Protein Extract against Six Oral pathogens in In vitro condition

“…asper has been used in traditional medicine as decoction and pastes for wound infections. Several studies have reported that S. asper plant alcohol extract possess antibacterial and antiinflammatory activities (Wongkham et al, 2001) (Fig. 1).…”

Bioactive non-sterol triterpenoid fromStreblus asper: microwave-assisted extraction, HPTLC profiling, computational studies and neuro-pharmacological evaluation in BALB/c mice

“…1998;Nadkarni 2002). Scientific investigations have revealed various activities of S. asper such as anti-hepatitis B, analgesic, anticancer, anti-inflammatory, antioxidant and antimicrobial (Wongkham et al 2001;Phutdhawong et al 2004;Sripanidkulchai et al 2009;Basuri 2011;Chen et al 2012;Kumar et al 2012;Ibrahim et al 2013;Rao et al 2014). The literature also mentions that the stem bark of S. asper is a rich source of phyto-constituents, from which a number of compounds such as a-amyrin acetate, lupeol acetate, b-sitosterol, a-amyrin, lupeol and diol, strebloside and mansonin have been isolated (Prakesh et al 1992;Warrier 1996;Khare 2004;Rastogi et al 2006).…”