Antimicrobial activity of kojic acid from endophytic fungus Colletotrichum gloeosporioides isolated from Sonneratia apetala, a mangrove plant of the Sundarbans

Nurunnabi, Tauhidur Rahman; Al-Majmaie, Shaymaa; Nakouti, Ismini; Nahar, Lutfun; Rahman, Suzanah Abdul; Sohrab, Md. Hossain; Billah, Morsaline; Ismail, Fyaz M.D.; Sharples, George P.; Sarker, Satyajit D.

doi:10.4103/1995-7645.233183

Cited by 27 publications

(4 citation statements)

References 17 publications

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“…(Tibpromma et al, 2018). Colletotrichum gloeosporioides with antimicrobial activity was obtained from Sonneratia apetala (Nurunnabi et al 2018).…”

Section: Discussionmentioning

confidence: 99%

Antibacterial profiling of endophytic fungi sourced from Justicia betonica, a medicinal plant from the secluded Western Ghats region

2021

ajom

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The present study focused on exploring the endophytic fungal diversity associated with an ethnomedicinally valued plant, Justicia betonica located in the Western Ghats region of Karnataka and evaluation of their antibacterial potential. A total of 210 endophytic fungal isolates were obtained from healthy leaf and stem tissues. The isolates were grouped into 17 distinct genera, including morphospecies. The Colletotrichum is one of the most predominant genera representing 18.1% of the total isolates, followed by Cladosporium (14.8%), Pestalotiopsis (7.14%), and Alternaria (6.7%). The Shannon-wiener diversity (H) showed that fungal diversity in both plant tissues does not have significant differences. The antibacterial potential of the isolates was evaluated using a primary agar plug diffusion technique in which 28 isolates showed prominent antibacterial activity. Nine isolates that showed the highest antibacterial activity were subjected to secondary antibacterial screening using ethyl acetate extracts. The extracts showed varying inhibitory activity against both the pathogens Escherichia coli and Staphylococcus aureus with inhibition zone ranging from 14 to 32 mm. A Xylaria sp. designated as PJJBLF53 displayed the maximum inhibition zone against both the pathogens tested when compared to the standard antibiotic, gentamicin. The study indicates that J. betonica harbors diverse endophytic fungi that possess potent antibacterial potential.

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“…(Tibpromma et al, 2018). Colletotrichum gloeosporioides with antimicrobial activity was obtained from Sonneratia apetala (Nurunnabi et al 2018).…”

Section: Discussionmentioning

confidence: 99%

Antibacterial profiling of endophytic fungi sourced from Justicia betonica, a medicinal plant from the secluded Western Ghats region

2021

ajom

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“…Kojic acid (5-hydroxy-2-hydroxymethyl-4H-pyran4one, KA) is a natural organic acid produced by fungi such as Aspergillus oryzae (A. oryzae) and Aspergillus favus (A. favus) [20,21]. KA and its derivatives are widely used as food additives, presenting interesting bioactivities for preventing enzymatic browning of shrimp and antimicrobial and antiviral activities [22,23].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Antibacterial and Antibiofilm Properties of Kojic Acid against Aeromonas sobria and Staphylococcus saprophyticus

Qian

Lan

et al. 2023

Journal of Food Quality

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Biofilms composed of microbes and extracellular polymeric substances (EPSs) pose a significant risk to human health and lead to economic loss in the food industry. In this study, the antimicrobial and antibiofilm properties of kojic acid (KA) against Aeromonas sobria (A. sobria) and Staphylococcus saprophyticus (S. saprophyticus) were investigated by determining the leakage of DNA and protein, cell morphology, biofilm formation, the metabolic activity of biofilms, excretion of EPS, and biofilm architecture. The results indicated that the values of minimum inhibitory concentration (MIC) of A. sobria and S. saprophyticus after KA treatment were 0.4 mg/mL and 1.6 mg/mL, respectively. 1 × MIC KA showed unignorable antimicrobial activity against the two bacteria, leading to alterations in the bacterial physicochemical characteristics and cell death. Sub-MICs of KA can inhibit biofilm formation and decrease the metabolic activity and excretion of EPS, and these inhibition effects were in a dose-dependent manner. These results were further confirmed by the visual images obtained from scanning electron microscopy (SEM) and confocal laser scanning microscopy (CLSM). Moreover, S. saprophyticus is more susceptible to KA in inhibiting biofilm formation, and for A. sobria, changes in the cell structure and the permeability of the cell membrane were more obvious. This research highlighted the antibacterial and antibiofilm activity of KA against A. sobria and S. saprophyticus.

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“…It has been well established that ecology of plants has enormous effect on the genetic diversity of the endophytes obtained from the plants and this has enabled them to produce different types of metabolites [11]. It is noteworthy to mention that a very few studies have been conducted to explore the diversity of mangrove endophytic fungi from the Sundarbans, the largest mangrove forest in the world [12][13][14][15]. We hypothesize that the endophytic fungi isolated from mangrove plants thriving at highly saline environment would produce a myriad of bioactive compounds to provide protection against salinity-induced abiotic-stress [16,17], and these compounds may possess bioactive properties.…”

Section: Introductionmentioning

confidence: 99%

Molecular identification and antimicrobial activity of endophytic fungi isolated from Heritiera fomes (Buch. -Ham), a mangrove plant of the Sundarbans

Nurunnabi

Sarwar²,

Sabrin

et al. 2020

Beni-Suef Univ J Basic Appl Sci

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Background Endophytic fungi play a vital role in plant defense system by secreting various antimicrobial agents. To evaluate the antimicrobial activity of the endophytic fungi of the mangrove plant Heritiera fomes (Buch. -Ham), plants were collected from the Sundarbans, Bangladesh. The endophytic fungi were subsequently isolated and identified. Results Fifty-five endophytic fungi were isolated from the leaves, root, and bark of H. fomes (Buch. -Ham). Genomic DNA was extracted for PCR (polymerase chain reaction) by specific primers to multiply ITS region and sequences were determined. Nucleotide sequence data were submitted to the Genbank and accession number for each fungal strain was obtained. Antimicrobial activity of the ethyl acetate (EtOAc) and methanolic extracts of eleven species from both fermentation and mycelium, respectively, were analyzed by microtiter plate-based antimicrobial assay incorporating resazurin as an indicator of cell growth against two Gram-positive bacteria namely Staphylococcus aureus NCTC 12981 and Micrococcus luteus NCTC 7508, two Gram-negative bacteria namely Escherichia coli NCTC 12241 and Pseudomonas aeruginosa NCTC 12903, and a fungus Candida albicans ATCC 90028. All the endophytic fungal extracts exhibited antimicrobial activities against more than one-tested pathogenic microbial strains. Overall, methanolic extracts showed greater activity than EtOAc extracts. Pseudopestalotiopsis camelliae-sinensis, Pestalotiopsis microspora, and Penicillium copticola were the most active endophytic fungal strains and exhibited strong inhibitory activity against the microorganisms under investigation and their MIC values ranged from 0.0024 to 5.0 mg/mL. Methanolic extracts of both P. camelliae-sinensis and P. microspora showed the highest antibacterial activity (MIC value of 0.0024 mg/mL) against P. aeruginosa NCTC 12903. Conclusion This study showed that the isolated and identified endophytic fungi from H. fomes (Buch. -Ham) could be potential sources of antimicrobial agents.

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Antimicrobial activity of kojic acid from endophytic fungus Colletotrichum gloeosporioides isolated from Sonneratia apetala, a mangrove plant of the Sundarbans

Cited by 27 publications

References 17 publications

Antibacterial profiling of endophytic fungi sourced from Justicia betonica, a medicinal plant from the secluded Western Ghats region

Antibacterial profiling of endophytic fungi sourced from Justicia betonica, a medicinal plant from the secluded Western Ghats region

Evaluation of Antibacterial and Antibiofilm Properties of Kojic Acid against Aeromonas sobria and Staphylococcus saprophyticus

Molecular identification and antimicrobial activity of endophytic fungi isolated from Heritiera fomes (Buch. -Ham), a mangrove plant of the Sundarbans

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