Antimicrobial activity of some medicinal plants of the island Soqotra

Mothana, Ramzi A.; Lindequist, Ulrike

doi:10.1016/j.jep.2004.09.006

Cited by 234 publications

(153 citation statements)

References 15 publications

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“…The diameters of the inhibition zones were measured in millimeters. A positive result was defined as a zone of 9 mm or more in diameter of inhibited growth of bacterial strain and indicated the presence of antimicrobial activity (Mothana & Lindequist, 2005). The estimations were carried out in liquid media which contained the most active fraction.…”

Section: Agar Diffusion Methods and Estimation Of Minimal Inhibitory Cmentioning

confidence: 99%

“…Natural compounds from medicinal plants have aroused much attention, and increasing efforts have been made to search for plant-derived antioxidants and antimicrobial agents (Belinha et al, 2008;Mothana & Lindequist, 2005). On the other hand, photosensitization caused by medicinal plants used in folk medicine, has been involved with a number of clinical skin syndromes, like dermatitis (Freitas et al, 2000;Montoya et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of antimicrobial, antioxidant and phototoxic activities of extracts and isolated compounds from Stachytarpheta cayennensis (Rich.) Vahl, Verbenaceae

Souza¹,

Silva²,

Machado³

et al. 2010

Rev. bras. farmacogn.

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RESUMO: "Avalição da atividade antimicrobiana, antioxidante e fototóxica dos extratos e compostos isolados de Stachytarpheta cayennensis (Rich.) Vahl, Verbenaceae". Stachytarpheta cayennensis (Rich.) Vahl, Verbenaceae, é uma planta utilizada na medicina popular brasileira contra úlceras e lesões de pele. Internamente é usada contra inflamações, febre, doenças renais e aterosclerose. Essa planta foi estudada com o objetivo de identificar os compostos bioativos majoritários que possam justificar seu uso terapêutico contra lesões de pele e arteriosclerose. A atividade antioxidante do extrato bruto etanólico, partições e os compostos majoritários isolados das raízes de S. cayennesis foi avaliada através de testes in vivo e in vitro. In vitro a atividade antioxidante foi avaliada pelo teste fotocolorimétrico do radical 2,2-difenil-1-picrilidrazil (DPPH•). In vivo, Saccharomyces cerevisiae, um modelo de célula eucariótica, foi utilizado tanto para avaliar a fototoxicidade quanto a capacidade antioxidante contra as espécies reativas de oxigênio (EROS) menadiona e peróxido de hidrogênio. O extrato, partições e os dois compostos majoritários isolados, verbascosídeo e ácido betulínico foram capazes de aumentar a sobrevivência e diminuir a peroxidação lipídica de S. cerevisiae contra EROS. Verbascosídeo apresentou atividade antimicrobiana moderada contra Streptococcus pyogenes, S.epidermidis e Staphylococcus aureus. O extrato etanólico e as partições testadas não apresentaram fototoxicidade, indicando que S. cayennensis é uma planta segura para o tratamento de lesões de pele e como possível ingrediente em cosméticos.Unitermos: Stachytarpheta cayennensis, antioxidante, antimicrobial, fototoxicidade, arilpropanoide glicosilado, ácido betulínico.ABSTRACT: Stachytarpheta cayennensis (Rich.) Vahl, Verbenaceae, plant extract, is a Brazilian medicinal plant externally used in folk medicine for purulent ulcers, skin lesions and internally for inflammations, fever, renal disorders and atherosclerosis. S. cayennesis was studied to identify potential bioactive compounds that may justify their therapeutic use against skin lesions and atherosclerosis. The antioxidant, antimicrobial and phototoxicity capacities of the crude ethanolic extract, fractions and isolated compounds from roots of S. cayennesis were evaluated through in vivo and in vitro tests. Strains of Saccharomyces cerevisiae, an eukaryotic cell model, were used to assess both the phototoxicity and the capacity to protect against the lethal oxidative stress caused by menadione and hydrogen peroxide. The extract, fractions and the two major isolated compounds, verbascoside and betulinic acid, of S. cayennensis were able to increase the tolerance and decrease the lipid peroxidation of S. cerevisiae to reactive oxygen species (ROS). The antioxidant activity was also evaluated by scavenging of 2,2-diphenyl-1-picrylhydrazyl (DPPH•). Verbascoside exhibited a moderate antimicrobial activity against Streptococcus pyogenes, S.epidermidis and Staphylococcus aureus. Neither the ethanol...

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Section: Agar Diffusion Methods and Estimation Of Minimal Inhibitory Cmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Evaluation of antimicrobial, antioxidant and phototoxic activities of extracts and isolated compounds from Stachytarpheta cayennensis (Rich.) Vahl, Verbenaceae

Souza¹,

Silva²,

Machado³

et al. 2010

Rev. bras. farmacogn.

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“…Plant extracts represent a continuous effort to find new compounds with the potential to act against multi-resistant bacteria. Approximately 20% of the plants found in the world have been submitted to pharmacological or biological test, and a substantial number of new antibiotics introduced on the market are obtained from natural or semi-synthetic resources (Mothana and Lindequist, 2005).…”

Section: Introductionmentioning

confidence: 99%

Antibacterial and antifungal activities of different parts of Tribulus terrestris L. growing in Iraq

Al-Bayati

Al-Mola

2008

J. Zhejiang Univ. Sci. B

144

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“…Around 20% of the plants found on the planet have been submitted to the pharmaceutical or organic test and a manageable number of new anti-infection agents presented in the market are gotten from regular or semimanufactured assets [2].…”

Section: Introductionmentioning

confidence: 99%

Preliminary Phytochemical Screening and in Vitro Antimicrobial Activity of Ethanolic Extract of Whole Aerial Part of the Herb Leucas Plukenetii Spreng (Family-Laminaceae)

Borah¹,

Dash²,

Dash³

et al. 2017

Int J Curr Pharm Sci

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Objective: To evaluate the antimicrobial activity of ethanolic extract of Leucas Plukenetii Spreng (family-laminaceae) in conjugation with phytochemical analysis. Methods:The ethanolic extract of whole aerial parts of the herb Leucas Plukenetiispreng (family-laminaceae) was prepared and analysed for phytochemical constituents using standard methods. The antimicrobial activity of the plant extract was examined against 2 bacterial strains among one is gram positive and other is gram negative and 2 fungal strains using agar well diffusion method.Results: The present investigation shows the phytochemical analysis, antimicrobial activity of the ethanolic extract of the plant Leucas Plukenetii Spreng. Various phytochemical analyses revealed the presence of alkaloids, saponin, flavonoids, carbohydrates, glycosides, Steroids, proteins and amino acids and tannins. The antimicrobial activity of the ethanolic extract of the plant showed significant result against all the of the test organisms. Conclusion:The present study concluded that ethanolic extract of whole aerial parts of the Leucas Plukenetii Spreng contains the high presence of phytochemicals. The ethnaolic extract of the plant was found to possess promising antimicrobial activity when compared with the standards.

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Antimicrobial activity of some medicinal plants of the island Soqotra

Cited by 234 publications

References 15 publications

Evaluation of antimicrobial, antioxidant and phototoxic activities of extracts and isolated compounds from Stachytarpheta cayennensis (Rich.) Vahl, Verbenaceae

Evaluation of antimicrobial, antioxidant and phototoxic activities of extracts and isolated compounds from Stachytarpheta cayennensis (Rich.) Vahl, Verbenaceae

Antibacterial and antifungal activities of different parts of Tribulus terrestris L. growing in Iraq

Preliminary Phytochemical Screening and in Vitro Antimicrobial Activity of Ethanolic Extract of Whole Aerial Part of the Herb Leucas Plukenetii Spreng (Family-Laminaceae)

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