Antimicrobial agents for treating uncomplicated urinary tract infection in women

Drug Utilization Pattern and Adverse Drug Reaction Monitoring in Urinary Tract Infection Patients in a Tertiary Care Hospital

“…Our analysis reflects the increased number of symptomatic cases having fever, pain in micturition and hematurea in comparison to asymptomatic cases. 13 The isolated pathogens in urine culture were of both from positive and gram negative type as also reported earlier. 14 Susceptibility to UTI infection showed past history of biologic factors like UTI, diabetes mellitus, urinary obstruction, incontinence.…”

Incidence of Urinary Tract Infection (UTI) Among Pregnant Women Attending Antenatal Clinics at Some Selected Hospitals in Aba, Southeastern Nigeria

“…The causative agents of UTIs can either be bacteria, viruses, fungi and other parasites (5). Bacteria mostly incriminated in UTI include Echerichia coli and Staphylococcus saprophyticus with remainder caused by Proteus and other Gram-negative rods (6). The occurrence of one or two of these organisms over others is dependent on the environment.…”

Treatment of acute uncomplicated cystitis - A clinical review

“…On the contrary, the infection may cure in 25-42% of women without treatment or inappropriate treatment [1]. However, data do not justify witholding antimicrobial therapy in acute cystitis, because treatment with placebo is associated with prolongation of symptoms as well as a small risk of progression to pyelonephritis [1,6,7,19]. Thus, uncomplicated UTI is one of the most common indications for antimicrobial use in medicine.…”

“…They believe that a short course of fluoroquinolones for cystitis probably adds little pressure to spread of resistance compared with the widespread not indicated use of fluoroquinolones. In any case, in a recent systematic review and meta-analysis the authors concluded that fluoroquinolones have no added value over other antibitoic groups (nitrofurantoin, beta-lactams and trimthoprim-sulfamthoxazole) for the treatment of acute uncomplicated UTI [19]. Moreover, the U.S. Food and Drug Administration advises that the serious side effects assoicated with fluoroquinolone antibarerial drugs generally otuweigh the benefits for patients with non serious infections, such as uncomplicated urinary tract infections [39].…”