Antimicrobial and antileishmanial activity of essential oil from the leaves of Annona foetida (Annonaceae)

Costa, Emmanoel V.; Pinheiro, Maria Lúcia B.; Silva, Jefferson Rocha de Andrade; Maia, Beatriz Helena Lameiro de Noronha Sales; Duarte, Marta Cristina Teixeira; Amaral, Ana Cláudia F.; Machado, Gérzia Maria de Carvalho; Leon, Leonor L.

doi:10.1590/s0100-40422009000100015

Cited by 60 publications

(50 citation statements)

References 19 publications

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“…This result was in good agreement with that found in other Annona species as: A. densicoma (0.1% m/m) , A. muricata (0.0002%, 0.01% m/m) (Kossouoh et al, 2007;Fournier et al, 1999), A. squamosa (0.12% m/m) (Garg & Gupta, 2005) and A. foetida (0.01% m/m) (Costa et al, 2009).…”

Section: Resultssupporting

confidence: 91%

“…However more investigations are (Table 2). A similar behavior was observed against the same protozoa with the A. foetida oil (IC50 27.2 µg/ mL) (Costa et al, 2009). Meanwhile, against the other two same Leishmania species, the volatile oil from A. foetida was more active than this of A. coriacea.…”

Section: Resultssupporting

confidence: 73%

“…In the essential oil from A. foetida, a similar profile to that of A. coriacea was found as it was seen the sesquiterpenes predominance and also in relation to bicyclogermacrene and (E)-caryophyllene (Costa et al, 2009).…”

Section: Resultssupporting

confidence: 65%

“…In contrast, although the sesquiterpenes of the volatile oil from A. foetida had been the main compounds similarly to that from A. coriacea, monoterpenes were not in its composition (Costa et al, 2009).…”

Section: Resultsmentioning

confidence: 79%

“…The antiprotozoal activity of the volatile oil from another Annona species (Costa et al, 2009) motivated this study to identify those constituents from the A. coriacea leaves and also to evaluate its potential anti-leishmanial and trypanocidal in vitro activities.…”

Section: Introductionmentioning

confidence: 99%

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Chemical constituents of the volatile oil from leaves of Annona coriacea and in vitro antiprotozoal activity

Siqueira

Oliani

Sartoratto³

et al. 2011

Rev. bras. farmacogn.

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Abstract:The essential oil of the leaves from Annona coriacea Mart., Annonaceae, was extracted by hydrodistillation in a Clevenger apparatus and analyzed by GC/MS and GC/FID. The oil yield was 0.05% m/m. Sixty compounds were identified, in a complex mixture of sesquiterpenes (76.7%), monoterpenes (20.0%) and other constituents (3.3%). Bicyclogermacrene was its major compound (39.8%) followed by other sesquiterpenes. Most of the monoterpenes were in low concentration (<1%). Only β-pinene and pseudolimonene presented the highest level of 1.6%. The volatile oil presented anti-leishmanial and trypanocidal activity against promastigotes of four species of Leishmania and trypomastigotes of Trypanosoma cruzi, showing to be more active against Leishmania (L.) chagasi (IC50 39.93 µg/mL) (95% CI 28.00-56.95 µg/mL).

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Section: Resultssupporting

confidence: 91%

Section: Resultssupporting

confidence: 73%

Section: Resultssupporting

confidence: 65%

Section: Resultsmentioning

confidence: 79%

Section: Introductionmentioning

confidence: 99%

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Chemical constituents of the volatile oil from leaves of Annona coriacea and in vitro antiprotozoal activity

Siqueira

Oliani

Sartoratto³

et al. 2011

Rev. bras. farmacogn.

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Anti‐Parasitic Activity of Essential Oils and their Active Constituents against Plasmodium, Trypanosoma and Leishmania

Béro

Kpoviessi

Quetin-Leclercq

2014

Novel Plant Bioresources

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Essential‐Oil Composition, Antileishmanial, and Toxicity Study of Artemisia abyssinica and Satureja punctata ssp. punctata from Ethiopia

Tariku

Hymete

Hailu

et al. 2010

Chemistry & Biodiversity

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Essential oils of Artemisia abyssinica and Satureja punctata ssp. punctata from Ethiopia were analyzed by GC and GC/MS, and screened for leishmanicidal activity against promastigote and axenic amastigotes of Leishmania donovani and L. aethiopica, including toxicity studies on human monocytic leukemia cells (THP-1) and erythrocytes in vitro. GC/MS of A. abyssinica oil revealed 67 compounds (99.94%) with the major constituents yomogi alcohol (38.47%), artemisyl acetate (24.88%), and artemisia alcohol (6.70%), and oxygenated monoterpenes (84.00%) as the dominant group. The oil of S. punctata contained 67 compounds (99.49%) with the main constituents geranial (27.62%), neral (21.72%), alpha-bisabolol (13.62%), and (E)-nerolidol (4.82%), of which oxygenated mono- and sesquiterpenes (58.39 and 26.91%, resp.) showed highest abundance. Both oils showed effect on promastigotes (MIC 76.5 to 312.5 nl/ml) and amastigotes (EC(50) 4.06 to 131.00 nl/ml) of L. donovani and L. aethiopica, and varying toxicities on THP-1 cells (CC(50) 0.013 to 350 nl/ml with selectivity index between 0.001 and 28) and erythrocytes (with LC(50) 0.35 to 1.52 microl/ml). S. punctata oil exerted highest activity against both Leishmania sp. and toxicity. The revealed antileishmanial activities support further isolation and investigation of oil constituents for in vitro/in vivo evaluation.

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Antimicrobial and antileishmanial activity of essential oil from the leaves of Annona foetida (Annonaceae)

Cited by 60 publications

References 19 publications

Chemical constituents of the volatile oil from leaves of Annona coriacea and in vitro antiprotozoal activity

Chemical constituents of the volatile oil from leaves of Annona coriacea and in vitro antiprotozoal activity

Anti‐Parasitic Activity of Essential Oils and their Active Constituents against Plasmodium, Trypanosoma and Leishmania

Essential‐Oil Composition, Antileishmanial, and Toxicity Study of Artemisia abyssinica and Satureja punctata ssp. punctata from Ethiopia

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