Antimicrobial, anticoagulant and antiplatelet activities of green synthesized silver nanoparticles using Selaginella (Sanjeevini) plant extract

Dakshayani, S.S.; Marulasiddeshwara, M.B.; Kumar, M. Vijaya; Ramesh, Golla; Kumar, P. Raghavendra; Sannaningaiah, Devaraja; Hosamani, Rashmi C

doi:10.1016/j.ijbiomac.2019.01.222

Cited by 96 publications

(10 citation statements)

References 54 publications

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“…Manoevering of particles at nanoscale tends to gain unique properties for use in various applications, viz., nano-generators, drug delivery system, and medical imaging [1][2][3][4]. Their efficiency to improve solubility, half-life, and sustained release of drugs find its application more appropriate in drug delivery [5]. In the current situation, the nano-biotechnology is one among the most energetic platform, explore the contemporary substantial discipline where the plants and various plant products find an imperious use in the fabrication of nanoparticles [6].…”

Section: Introductionmentioning

confidence: 99%

Eco-friendly approach in synthesis of silver nanoparticles and evaluation of optical, surface morphological and antimicrobial properties

Selvaraj¹,

Sagadevan

Muthukrishnan

et al. 2019

J Nanostruct Chem

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Silver nanoparticles (Ag NPs) were synthesized using Alternanthera sessilis leaf and Oregano root extract in an eco-friendly fashion and their significant physicochemical and optochemical properties were ascertained for nano-defined characteristics. The UV-visible spectrum showed a single and distinct absorbance peak at 433 nm (Alternanthera sessilis) and 425 nm (Oregano), typical SPR (surface plasmon resonance) for silver. Structural studies revealed nano-crystal with face centre cubic (FCC) symmetry with monodispersed nature. SEM studies showed spherical-shaped particles and the purity determined from EDX spectrum. The synthesized Ag NPs showed that antibacterial activity was studied. There was a significant inhibitory effect toward clinically important pathogens viz. B. subtilis, S. aureus, P. aeruginosa, and E. coli exposed to Ag NPs at different concentrations.

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Section: Introductionmentioning

confidence: 99%

Eco-friendly approach in synthesis of silver nanoparticles and evaluation of optical, surface morphological and antimicrobial properties

Selvaraj¹,

Sagadevan

Muthukrishnan

et al. 2019

J Nanostruct Chem

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“…Sondi and Salopek-Sondi (2004) reported the action mode of the penetration of Ag-NPs nanoparticles into E. coli and studied their effects on the bacterial plasma membrane structure could increase the membrane permeability and the entrance of Ag-NPs inside the bacterial cell. That resulted in DNA damages and alteration of the bacterial membrane, which may affect bacterial metabolism, including bacterial respiration, resulting in cell death as a consequence of the consumption of ATP (El-Naggar et al, 2017;Sur et al, 2018;Dakshayani et al, 2019;Hamouda et al, 2019). Li et al (2008) investigated the antibacterial effect of Ag-NPs on E. coli by TEM and found great damage to the bacterial cell membrane and inhibition of the function of some enzymes.…”

Section: Discussionmentioning

confidence: 99%

Green Synthesis of Silver Nanoparticles Using Lactic Acid Bacteria: Assessment of Antimicrobial Activity

Syame¹,

Mansour²,

Khalaf³

et al. 2020

WVJ

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The biosynthesis of silver nanoparticles (Ag-NPs) is a new methodology in nanotechnology with a hopeful implementation in medicine, food control, and pharmacy. The objective of the present research was to conduct a green synthesis of Ag-NPs using the cell-free supernatant of Lactobacillus plantarum and Lactobacillus brevis and evaluate their antibacterial and antifungal activities. The production of Ag-NPs was confirmed by the color alteration from yellow to brown. Using the UV-visible spectrophotometer, the biosynthesized Ag-NPs indicated an absorption peak at 410 nm. The transmission electron microscope was used for the determination of the size and morphology of the nanoparticles. Nanoparticles appeared in spherical or polyhedral form, poly-dispersed and their diameter ranged from 5 to 40 nm. The X-ray diffraction analysis exhibited the crystalline nature of the particles with a face-centered cubic (FCC) structure. The biosynthesized Ag-NPs were evaluated for their antimicrobial efficiency using the agar well diffusion method. The antibacterial activity of Ag-NPs was more potent against Gram-negative bacteria than Gram-positive bacteria. Ag-NPs synthesized from Lactobacillus plantarum recorded the maximum activity against Escherichia coli (ATCC® 10536™) and Pseudomonas (ATCC® 27853™) bacteria, while those synthesized from Lactobacillus brevis recorded the maximum activity against Escherichia coli (ATCC® 35218™). Ag-NPs synthesized from Lactobacillus plantarum and Lactobacillus brevis showed antifungal activity against Candida albicans (ATCC® 10231™). The effect of these nanoparticles on Escherichia coli (ATCC® 10536™) was examined and imaged by a transmission electron microscope that indicated damage to the plasma membrane and cell wall. In conclusion, the biosynthesized Ag-NPs have applications as antimicrobial agents in the medicine and food industry.

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“…Terdapat tiga dari 19 jenis ekstrak metanol dari tumbuhan yang diuji terkonfirmasi memiliki aktivitas antibakteri yang kuat, yaitu B. acutangula, P. indicus, dan Selaginella sp. (Dakshayani et al, 2019;Khan & Omoloso, 2003;Kong et al, 2020). Sisa jenis tumbuhan uji lainnya sejauh ini belum ditemukan adanya laporan penelitian terkait khasiat antimikroba.…”

Section: Uji Pendahuluan Antimikrobaunclassified

Kajian Etnofarmasi Dan Fitokimia Tumbuhan Obat Kampung Adat Urug, Kecamatan Sukajaya, Kabupaten Bogor, Jawa Barat

Syahputra

Astuti

Piter

et al. 2021

J. Tumbuhan Obat Indonesia

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ABSTRACT Knowledge and arts of the traditionally use of medicinal plant are valuable assets of Indonesian culture, which should be documented and preserved. Simultaneously, the plant that are traditionally used for health care should be investigated, particularly regarding their chemical constituents, biological activities and their safety, as well. This study aimed to inventory of medicinal plants used by people from Kampung Adat Urug, a Sundanese traditional village. This community still practices their traditional way of life, including how to maintain health and to treat illness. This study began with an ethnobotanical survey using Participation Observatory Method (POM) and interviewing the selected traditional healers. Data analysis was carried out by calculating Use Value (UV), Relative Frequency of Citation (RFC), and Relative Importance (RI) of plant species. The study revealed 29 medicinal plants used by Kampung Urug community. Five medicinal plants (Ixora salicifolia, Scleria levis, Hippobroma longiflora; Pterocarpus indicus and Pothos junghuhnii) showed high level of UV, RFC, and RI. Those species were found to be potential in treating various neglected diseases, women health care during pregnancy, postpartum illness, and maintaining health care in general. Besides, there were four plants extracts, each from Barringtonia acutangula; Pterocarpus indicus; Selaginella cf. lana and Pothos junghuhnii which showed potent inhibition against Staphylococcus aureus. The phytochemical screening of the above extracts showed various major constituents, particularly phenolics and flavonoids. Keywords: Ethnopharmacy, Kampung Urug, Phytochemistry ABSTRAK Pengetahuan dan seni tentang penggunaan tumbuhan obat merupakan salah satu kekayaan budaya bangsa Indonesia yang harus didokumentasikan dan dilestarikan. Secara bersamaan tumbuhan obat yang digunakan untuk pemeliharaan kesehatan dan obat itu juga harus diteliti, khususnya kandungan kimia dan bioaktifitasnya serta divalidasi khasiat dan keamanan penggunaannya. Adapun tujuan dari penelitian ini adalah untuk menginventarisasi penggunaan tumbuhan obat oleh salah satu masyarakat adat Suku Sunda yang tinggal tidak jauh dari kota Bogor yang dikenal dengan nama Kampung Adat Urug. Mereka hidup secara tradisional termasuk bagaimana memelihara kesehatan dan mengobati penyakit. Kajian ini dimulai dengan melakukan survei etnobotani menggunakan metode Participation Observatory Method (POM) dan mewawancarai beberapa dukun terpilih menggunakan analisis Use Value (UV), Relative Frequency of Citation (RFC), dan Relative Importance (RI). Pada kegiatan ini telah terkumpul 29 jenis tumbuhan obat, dibuat spesimen herbariumnya dan disiapkan juga ekstrak metanol dari tumbuhan obat yang dikoleksi tersebut. Berdasarkan metode POM dan wawancara beberapa dukun terpilih menggunakan analisis UV, RFC, dan RI, terpilih lima jenis tumbuhan obat, yaitu: Ixora salicifolia, Scleria levis, Hippobroma longiflora, Pterocarpus indicus dan Pothos junghuhnii, yang potential digunakan untuk berbagai penyakit terabaikan, perawatan wanita hamil dan setelah melahirkan serta untuk pemeliharaan kesehatan secara umum. Berdasarkan studi pustaka terdapat empat ekstrak tumbuhan; Barringtonia acutangula, P. indicus, Selaginella cf. plana, dan P. junghuhnii yang menghambat kuat pertumbuhan bakteri Staphylococcus aureus yang sering menyebabkan infeksi secara umum. Hasil penapisan fitokimia terlihat bahwa ekstrak-ekstrak yang aktif antimikroba di atas memperlihatkan adanya kandungan senyawa kimia khususnya senyawa fenolik dan flavonoid yang diperlukan untuk perencanaan kajian-kajian isolasi dan karakterisasi kandungan senyawa aktif yang ada. Kata kunci: Etnofarmasi, Fitokimia, Kampung Urug

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Antimicrobial, anticoagulant and antiplatelet activities of green synthesized silver nanoparticles using Selaginella (Sanjeevini) plant extract

Cited by 96 publications

References 54 publications

Eco-friendly approach in synthesis of silver nanoparticles and evaluation of optical, surface morphological and antimicrobial properties

Eco-friendly approach in synthesis of silver nanoparticles and evaluation of optical, surface morphological and antimicrobial properties

Green Synthesis of Silver Nanoparticles Using Lactic Acid Bacteria: Assessment of Antimicrobial Activity

Kajian Etnofarmasi Dan Fitokimia Tumbuhan Obat Kampung Adat Urug, Kecamatan Sukajaya, Kabupaten Bogor, Jawa Barat

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