Antimicrobial, antioxidant and cytotoxic activities of selected medicinal plants from Yemen

Al-Fatimi, Mohamed; Wurster, Martina; Schröder, G.; Lindequist, Ulrike

doi:10.1055/s-2006-950074

Cited by 65 publications

(78 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In recent years however, the situation has changed and the systematic screening of the biological interaction between microorganisms and plant products has been recognized as a valuable source of several compounds able to control the survival of pathogen microorganisms (Al-Fatimi et al, 2007). An extensive body of research has demonstrated that essential oils and their main components possess a wide spectrum of biological activity, which may be of great importance in several fields, from food chemistry to pharmaceutics (Knowles et al, 2000;Cristiani et al, 2007).…”

Section: Candida and Criptococcus Genus Are Known As The Yeasts Most mentioning

confidence: 99%

Efficacy of Origanum essential oils for inhibition of potentially pathogenic fungi

Souza

Lima

Guedes

et al. 2010

Braz. J. Pharm. Sci.

View full text Add to dashboard Cite

show abstract

Section: Candida and Criptococcus Genus Are Known As The Yeasts Most mentioning

confidence: 99%

Efficacy of Origanum essential oils for inhibition of potentially pathogenic fungi

Souza

Lima

Guedes

et al. 2010

Braz. J. Pharm. Sci.

View full text Add to dashboard Cite

show abstract

“…Furthermore, a sesquiterpene lactone isolated from I. viscosa flowers possessed in vitro efficacy against Microsporum canis, M. gypseum and Trichophyton mentagrophytes (Abu Zarga et al 1998;Cafarchia et al 2002). The herbaceous annual plant nightshade, due to its high content of steroidal alkaloids, showed antifungal activity against 11 agronomically important fungi including: Aspergillus spp, Rhizopus spp, Fusarium spp, Mucor mucedo, Bipolaris oryzae and Rhizoctonia solani (Muto et al 2006;Zhou et al 2006;AL-Fatimi et al 2007). The current investigation aimed at in vitro and in vivo evaluation of seven plant extracts and their fractions for the control of P. italicum.…”

Section: Introductionmentioning

confidence: 99%

In Vitro and In Vivo Activity of Selected Plant Crude Extracts and Fractions Against Penicillium Italicum

Kanan¹,

Al-Najar²

2009

Journal of Plant Protection Research

View full text Add to dashboard Cite

Abstract:The objective of this study is to evaluate (in vitro and in vivo) seven plant extracts and their liquid fractions against four Penicillium italicum isolates. The in vitro study revealed that a concentration 520 µg/ml of crude extract of sticky fleabane leaves or cinnamon bark generated maximum percentage inhibition of 54% and 43%, respectively, against tested fungal isolates. A concentration of 130 µg /ml from each extract (except harmal and garlic where, 390 µg/ml were required) caused complete inhibition of fungal growth of isolates Pi.1 and Pi.3 infecting orange fruit. A concentration of 130 µg/ml of nightshade fruit, fenugreek or sticky fleabane extract inhibited completely the growth of isolates Pi.3 and Pi.5 infecting lemon fruits, whereas a concentration of 390 µg/ml was required to inhibit the growth of isolate Pi.1. Methanolic fractions of cinnamon, garlic or sticky fleabane completely inhibited the growth of fungal isolates. The IC 50 values for these fractions were found to be in the range of: 11.2-24; 30.25-31.50; 25.0-36.0 µg/ml, respectively.A concentration 20 µg/ml of cinnamon hexane fraction inhibited the growth of the fungal isolates, with IC 50 values of 13, 13.75, 14 and 13 µg/ml, respectively, obtained against isolates Pi.1, Pi.3, Pi.5 and Pi.6. The nightshade hexane fraction completely inhibited the growth of isolates Pi.1 and Pi.3 with IC 50 values of 80 and 37.5 µg/ml, respectively. Cinnamon aqueous fraction completely inhibited the growth of isolates Pi.1 and Pi.5 (IC 50 were 61.25 and 58.5 µg/ml, respectively).

show abstract

“…F. carica (Ali et al, 2012) has been reported to contain high antioxidant activity, F. ingens (Chauke et. al., 2012) and F. vasta (Al-Fatimi et al, 2007) showed mild antioxidant activity where as no antioxidant activity reported on F. final.…”

Section: Introductionmentioning

confidence: 79%

Comparative profiling of biomarker psoralen in antioxidant active extracts of different species of genus <i>Ficus</i> by validated HPTLC method

Siddiqui¹,

Basudan²,

Al‐Rehaily³

et al. 2015

Afr. J. Trad. Compl. Alt. Med.

View full text Add to dashboard Cite

Background: A simple but sensitive HPTLC method was developed for the comparative evaluation of psoralen in antioxidant active extracts of leaves of five different species of genus Ficus (Ficus carica, Ficus nitida, Ficus ingens, Ficus palmata and Ficus vasta). Materials and Methods: HPTLC studies were carried out using CAMAG HPTLC system on Glass-backed silica gel 60F 254 HPTLC pre-coated plates using selected mobile phase toluene: methanol (9:1). The antioxidant activity was carried out, using DPPH free radical method. Results: Among all the five species of genus Ficus, F. palmata and F. carica exhibited comparatively good antioxidant activity in DPPH assay. The developed HPTLC method was found to give a compact spot for psoralen (R f = 0.55±0.001) at 305 nm. The regression equation and r 2 for psoralen was found to be Y= 4.516X+35.894 and 0.998. The quantification result revealed the presence of psoralen in only two species, F. carica (0.24%, w/w) and F. palmata (1.88%, w/w) which supported their supremacy for anti-oxidant potential over other species. The statistical analysis proved that the developed method was reproducible and selective. Conclusion: The developed method can be used as an important tool to assure the therapeutic dose of active ingredients in herbal formulations as well as for standardization and quality control of bulk drugs and in-process formulations. This method can also be employed for the further study of degradation kinetics and determination of psoralen in plasma and other biological fluids.

show abstract

Antimicrobial, antioxidant and cytotoxic activities of selected medicinal plants from Yemen

Cited by 65 publications

References 0 publications

Efficacy of Origanum essential oils for inhibition of potentially pathogenic fungi

Efficacy of Origanum essential oils for inhibition of potentially pathogenic fungi

In Vitro and In Vivo Activity of Selected Plant Crude Extracts and Fractions Against Penicillium Italicum

Comparative profiling of biomarker psoralen in antioxidant active extracts of different species of genus <i>Ficus</i> by validated HPTLC method

Contact Info

Product

Resources

About