Antimicrobial effect of sorbic acid-loaded chitosan/tripolyphosphate nanoparticles on Pseudomonas aeruginosa

Wang, Qian; Peng, Yue; Chai, Linna; Ding, Wu

doi:10.1016/j.ijbiomac.2022.11.220

International Journal of Biological Macromolecules

2023

DOI: 10.1016/j.ijbiomac.2022.11.220

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Antimicrobial effect of sorbic acid-loaded chitosan/tripolyphosphate nanoparticles on Pseudomonas aeruginosa

Qian Wang

Yue Peng

Linna Chai

et al.

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2024

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Asymmetric Construction of Substituted Purine Esters with Tunable N‐9/N‐7 Regioselectivity via Enzymatic Dynamic Kinetic Resolution

Liu,

Han,

et al. 2024

Adv Synth Catal

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We report an enzyme‐catalyzed dynamic kinetic resolution protocol for the one‐pot asymmetric synthesis of substituted purine derivatives with high product yield (up to 96%) and enantio purity (up to 99%). The controllable N‐9/N‐7 substitution, which posed formidable challenges in organic synthesis, could be accomplished by choosing different types of enzymes as the catalyst. This method was proved easily scalable and was successfully used to prepare a series of prodrugs of medicinally active acids. In addition, the biocatalysts exhibited good recyclability, indicating the potential of this strategy for practical applications in the pharmaceutical industry.

show abstract

Asymmetric Construction of Substituted Purine Esters with Tunable N‐9/N‐7 Regioselectivity via Enzymatic Dynamic Kinetic Resolution

Liu,

Han,

et al. 2024

Adv Synth Catal

View full text Add to dashboard Cite

show abstract

Review on chitosan-based antibacterial hydrogels: Preparation, mechanisms, and applications

Wang,

et al. 2024

International Journal of Biological Macromolecules

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Modeling and characterization of lenalidomide-loaded tripolyphosphate-crosslinked chitosan nanoparticles for anticancer drug delivery

Jafari,

Morsali,

Bozorgmehr

et al. 2024

International Journal of Biological Macromolecules

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Antimicrobial effect of sorbic acid-loaded chitosan/tripolyphosphate nanoparticles on Pseudomonas aeruginosa

Cited by 5 publications

References 50 publications

Asymmetric Construction of Substituted Purine Esters with Tunable N‐9/N‐7 Regioselectivity via Enzymatic Dynamic Kinetic Resolution

Asymmetric Construction of Substituted Purine Esters with Tunable N‐9/N‐7 Regioselectivity via Enzymatic Dynamic Kinetic Resolution

Review on chitosan-based antibacterial hydrogels: Preparation, mechanisms, and applications

Modeling and characterization of lenalidomide-loaded tripolyphosphate-crosslinked chitosan nanoparticles for anticancer drug delivery

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