Antimicrobial Effects of Ethanol Extracts of Korea Endemic Herb Plants

차재영,; 하세은,; 심선미,; 박종군,; 정연옥,; 김현중,; 박노복,

doi:10.5352/jls.2008.18.2.228

Cited by 6 publications

(1 citation statement)

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“…, , , (Jo et al, 2000). S. aureus Salmonella gallinarum , (Choi et al, 2002) , Pseudomonas aeruginosa Propionibacterium acnes (Cha et al, 2008 : 2012AA101) .…”

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Antibacterial Activity of Rhus javanica against the Fish Pathogens Vibrio ichthyoenteri and Streptococcus iniae

Kim¹,

Kim²,

Cho³

et al. 2014

Korean Journal of Fisheries and Aquatic Sciences

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The antibacterial activities of methanol extracts of 19 commercial herbal medicines were measured against the fish pathogens Vibrio ichthyoenteri and Streptococcus iniae, which cause several fish diseases. Rhus javanica showed the strongest antibacterial activity against V. ichthyoenteri and S. iniae. The methanol extract of R. javanica was extracted further using several organic solvents with different polarities. The extract from the ethyl acetate fraction showed strong activity against both fish pathogens. The minimum inhibitory concentration (MIC) of the R. javanica extract was 32 μg/mL for V. ichthyoenteri and 128 μg/mL for S. iniae. Further purification and isolation of the active compound (s) responsible for these activities and further study of the synergistic effect using combinations of antibiotics against pathogenic bacteria are needed.

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“…, , , (Jo et al, 2000). S. aureus Salmonella gallinarum , (Choi et al, 2002) , Pseudomonas aeruginosa Propionibacterium acnes (Cha et al, 2008 : 2012AA101) .…”

unclassified

Antibacterial Activity of Rhus javanica against the Fish Pathogens Vibrio ichthyoenteri and Streptococcus iniae

Kim¹,

Kim²,

Cho³

et al. 2014

Korean Journal of Fisheries and Aquatic Sciences

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Antimicrobial activities of Lindera obtusiloba Blume and Zanthoxylum piperitum DC extracts

Kim¹,

Do²,

Chung

2014

Korean Journal of Food Preservation

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Ethanol and hot water extracts were prepared from Lindera obtusiloba Blume (LO) and Zanthoxylum piperitum DC (ZP) and used to evaluate their antimicrobial activities and thermal stability against six foodborne pathogens (3 gram-positive and 3 gram-negative bacteria). The antimicrobial activities were assessed using the agar diffusion method, and the thermal stabilities of extracts were examined after heat treatment at 60, 70, 80, and 100℃ for 10 min. The zones of inhibition by the LO extract or the ZP extract of the tested microorganisms were in the range of 21-30 mm and 19-25 mm, respectively, at 100 mg/mL concentrations. The 60% ethanol extract and the hot water extracts from LO showed the strongest antimicrobial effects against MRSA and Staphylococcus aurues, respectively. For the extract from ZP, the strongest antimicrobial effect was shown against S. aurues by 60% ethanol, and the weakest antimicrobial effect was shown against E. coli by the hot water extracts. The ZP extracts showed that the gram-positive bacteria were more sensitive than gram-negative bacteria. For the thermal stability of the extracts, the antimicrobial effects stabilized after heat treatment. Overall, the data suggest that the extracts have a potential for application in various food products for which a natural antimicrobial additive is desired. Key words：Lindera obtusiloba

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Inhibitory Effects of Dansam and <italic>Dansam-eum</italic> on Reflux Esophagitis and Migration of Cancer Cells

Kwon¹,

An²,

Kong³

2022

J Int Korean Med

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Purpose: We examined the effects of Dansam (Salvia miltiorrhiza Bunge, SM) and Dansam-eum (DSE) on gastroesophageal reflux disease (GERD) and reflux esophagitis by comparing the inhibitory effects of SM and DSE with the representative treatment of PPI Omeprazole to determine if the effects of the prescription DSE based on Korean medicine are better than those of a single-use of SM.Methods: We performed experiments using both animal models and cancer cells.Results: Comparison of SM and DSE with PPI in the animal model tests revealed that the effects were superior for SM and DSE than for PPI in all categories (8-OHdG, p-IκB, PAR2, COX-1, cathelicidin, p-JNK, Caspase 3, ATP6V1B1, GRPR, serotonin, and NPY). In three categories (COX-1, serotonin, and NPY), SM and DSE showed superior results over the Controls. In the animal model tests, DSE was superior to SM in all categories except for serotonin. The anti-cancer effects observed in cancer cell tests revealed that SM and DSE had meaningful results in terms of cytotoxicity and cell movement rate, as well as in cancer cell apoptosis.Conclusions: We confirmed that SM and DSE can have effects on reflux esophagitis through the regulation of oxidative stress, inflammation, mucosal protection, apoptosis, proton pumping, and the enteroendocrine system in the stomach and esophagus. We also confirmed that SM and DSE have superior effects to those of PPI on all aspects, especially gastric mucosa protection and enteroendocrine system control. We also confirmed that SM and DSE have anti-cancer effects. Above all, we confirmed that DSE has superior effects on almost all aspects compared to using SM alone.

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Antimicrobial Effects of Ethanol Extracts of Korea Endemic Herb Plants

Cited by 6 publications

References 0 publications

Antibacterial Activity of Rhus javanica against the Fish Pathogens Vibrio ichthyoenteri and Streptococcus iniae

Antibacterial Activity of Rhus javanica against the Fish Pathogens Vibrio ichthyoenteri and Streptococcus iniae

Antimicrobial activities of Lindera obtusiloba Blume and Zanthoxylum piperitum DC extracts

Inhibitory Effects of Dansam and <italic>Dansam-eum</italic> on Reflux Esophagitis and Migration of Cancer Cells

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