Antimicrobial hydrogel microspheres for protein capture and wound healing

Lei, Lanjie; Wang, Xiangguo; Yu, Zhao; Su, Wentao; Lv, Qizhuang; Li, Dong

doi:10.1016/j.matdes.2022.110478

Cited by 50 publications

(34 citation statements)

References 38 publications

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“…Microfluidic electrospray devices are simply composed of capillaries ( Fig. 1 C) [ 66 ]. Although microfluidic electrospray technology is not widely used at present, it has also been applied to the production of microspheres.…”

Section: Processing Methods Of Microspheresmentioning

confidence: 99%

Progress in the application of sustained-release drug microspheres in tissue engineering

Ruan¹,

Su²,

Qin³

et al. 2022

Materials Today Bio

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Section: Processing Methods Of Microspheresmentioning

confidence: 99%

Progress in the application of sustained-release drug microspheres in tissue engineering

Ruan¹,

Su²,

Qin³

et al. 2022

Materials Today Bio

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“…The combination of VEGF and HAMA can promote endometrial regeneration and embryo implantation, while hyaluronic-acid hydrogel scaffolds can work with VEGF to promote endometrial hyperplasia after degradation. Therefore, this drug-loaded hydrogel has a good application prospect (Figure 7a) [129][130][131]. By selecting suitable responsive hydrogels or changing the structure of nanopores, hydrogels can be designed to have tunable drug-delivery effects.…”

Section: Drug Delivery and Tissue Engineeringmentioning

confidence: 99%

Current Understanding of the Applications of Photocrosslinked Hydrogels in Biomedical Engineering

Liu

Chen

et al. 2022

Gels

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Hydrogel materials have great application value in biomedical engineering. Among them, photocrosslinked hydrogels have attracted much attention due to their variety and simple convenient preparation methods. Here, we provide a systematic review of the biomedical-engineering applications of photocrosslinked hydrogels. First, we introduce the types of photocrosslinked hydrogel monomers, and the methods for preparation of photocrosslinked hydrogels with different morphologies are summarized. Subsequently, various biomedical applications of photocrosslinked hydrogels are reviewed. Finally, some shortcomings and development directions for photocrosslinked hydrogels are considered and proposed. This paper is designed to give researchers in related fields a systematic understanding of photocrosslinked hydrogels and provide inspiration to seek new development directions for studies of photocrosslinked hydrogels or related materials.

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“…Moreover, employing both fluid dynamics and shaped microchannels would lead to the fabrication of distinctive biomaterial carriers such as nanoparticles, microfibers, and microspheres [ 342 ]. In a recent study, Lei et al have developed a microfluidic platform to prepare magnetic chitosan microspheres (MCMs) to trigger angiogenesis and epithelization for wound healing with antibacterial activity [ 343 ]. As a result, the developed microfluidic platform enhanced the efficient fabrication of MCMs with uniform size and shape.…”

Section: Biomedical Applicationsmentioning

confidence: 99%

Biomedical Applications of Microfluidic Devices: A Review

et al. 2022

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Both passive and active microfluidic chips are used in many biomedical and chemical applications to support fluid mixing, particle manipulations, and signal detection. Passive microfluidic devices are geometry-dependent, and their uses are rather limited. Active microfluidic devices include sensors or detectors that transduce chemical, biological, and physical changes into electrical or optical signals. Also, they are transduction devices that detect biological and chemical changes in biomedical applications, and they are highly versatile microfluidic tools for disease diagnosis and organ modeling. This review provides a comprehensive overview of the significant advances that have been made in the development of microfluidics devices. We will discuss the function of microfluidic devices as micromixers or as sorters of cells and substances (e.g., microfiltration, flow or displacement, and trapping). Microfluidic devices are fabricated using a range of techniques, including molding, etching, three-dimensional printing, and nanofabrication. Their broad utility lies in the detection of diagnostic biomarkers and organ-on-chip approaches that permit disease modeling in cancer, as well as uses in neurological, cardiovascular, hepatic, and pulmonary diseases. Biosensor applications allow for point-of-care testing, using assays based on enzymes, nanozymes, antibodies, or nucleic acids (DNA or RNA). An anticipated development in the field includes the optimization of techniques for the fabrication of microfluidic devices using biocompatible materials. These developments will increase biomedical versatility, reduce diagnostic costs, and accelerate diagnosis time of microfluidics technology.

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Antimicrobial hydrogel microspheres for protein capture and wound healing

Cited by 50 publications

References 38 publications

Progress in the application of sustained-release drug microspheres in tissue engineering

Progress in the application of sustained-release drug microspheres in tissue engineering

Current Understanding of the Applications of Photocrosslinked Hydrogels in Biomedical Engineering

Biomedical Applications of Microfluidic Devices: A Review

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