Antimicrobial photodynamic therapy for the treatment of oral mucositis—A comparative study

Photodynamic Therapy with Tolonium Chloride and a Diode Laser (635 nm) in the Non-Surgical Management of Periodontitis: A Clinical Study

“…Previous studies have shown the presence of periodontopathogens, such as Aggregatibacter actinomycetemcomitans , in the depth of epithelial cells within periodontal pockets and outside the gingival tissues [ 29 , 30 ]. It seems that conventional mechanical debridement could be enhanced with PDT, which enables the disinfectant to penetrate the depth of the periodontal tissues due to the nature of the light (with deep tissue penetration capabilities) and the liquid solution used; therefore, this might have resulted in the achievement of a more comprehensive and profound disinfection [ 26 , 27 , 28 ]. This can suggest that PDT might be a valuable adjunct to conventional therapy, providing an enhanced and targeted approach for the treatment of periodontitis.…”

“…For instance, in odontology, PDT has demonstrated positive outcomes in treating pre-neoplastic lesions and leukoplakia of the oral cavity [ 24 ]. It has also shown promise in the preventive and curative management of oral complications arising from cancer treatment, such as oral mucositis [ 25 , 26 ], and treating oral candidiasis [ 27 ]. These are just a few of the indications that can be found in the existing literature.…”