Antimicrobial Properties of Green Tea Extract Against Cariogenic Microflora: An In Vivo Study

Ferrazzano, Gianmaria Fabrizio; Roberto, Lia; Amato, Ivana; Cantile, Tiziana; Sangianantoni, G; Ingenito, A

doi:10.1089/jmf.2010.0196

Cited by 91 publications

(75 citation statements)

References 20 publications

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“…There are previous published studies on the activity of tea components against bacteria responsible for oral diseases. Some research groups showed that tea extracts inhibited the attachment of bacteria to oral surfaces [32] and are effective against cariogenic microorganisms [23]. It was observed that rinsing the mouth with green tea led to a significant reduction of cariogenic bacteria like S. mutans and Lactobacillus [19,33].…”

Section: Microbiological Assays – Determination Of Minimum Inhibitorymentioning

confidence: 99%

Inhibitory activity of a green and black tea blend on Streptococcus mutans

Barroso

Ramalhete

Domingues³

et al. 2018

Journal of Oral Microbiology

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Through the years, tea consumption has been associated with good health, and some publications are related to oral health. The bioactive components of green tea are thought to be able to influence the process of caries formation through inhibition of proliferation of the streptococcal agent, interference with the process of bacterial adhesion to tooth enamel, and inhibition of glucosyl transferase and amylase; however, little is known about black tea and oral health. The aim of the present in-vitro study was to determine the inhibitory activity of a novel, patent-pending and proprietary blend of green and black tea aqueous extracts on Streptococcus mutans, a bacterium widely associated with plaque development and tooth decay. A minimum inhibitory concentration (MIC) of 12.5 mg/mL and a minimum bactericidal concentration (MBC) of 12.5 mg/mL was established against S. mutans, meaning that at concentrations of 12.5 mg/mL and higher, the proprietary tea blend is effective against the growth of S. mutans. This MIC concentration is lower than the ones reported in the literature for alcoholic black tea and green tea extracts tested separately. As a promising natural ingredient for oral health, this finding is a good indicator for the use of this proprietary blend of black and green tea water extracts.

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Section: Microbiological Assays – Determination Of Minimum Inhibitorymentioning

confidence: 99%

Inhibitory activity of a green and black tea blend on Streptococcus mutans

Barroso

Ramalhete

Domingues³

et al. 2018

Journal of Oral Microbiology

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“…Ferrazzano et al, 21 in their in vivo study, evaluated the antimicrobial effect of green tea extract on cariogenic microflora. Since varnish provides longer exposure than solutions and mouthrinses 22,23 and considering the lack of information on the efficacy of green tea varnish on caries formation, this study sought to assess the effect of green tea varnish on the depth of root caries.…”

Section: 5005/jp-journals-10024-2227mentioning

confidence: 99%

Effect of Green Tea Varnish on Depth of Root Caries

Daneshyar

Khamverdi

Toliat

et al. 2018

The Journal of Contemporary Dental Practice

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Aim: Root caries is a common, debilitating condition particularly in the elderly population, which can lead to tooth loss. Evidence shows that green tea has cariostatic effects. Considering the gap of information on green tea varnish, this study aimed to assess the efficacy of green tea varnish in the prevention of root caries. Materials and methods:This in vitro experimental study was performed on 42 sound premolars. Two layers of acid-resistant nail varnish were applied on root surfaces except for a window of 1 × 4 mm. The teeth were randomly divided into three groups (n = 14). Group I (control) received no intervention. Group II received green tea varnish applied on the roots every 48 hours for 21 days. Group III received green tea varnish every 24 hours for 21 days. Sections of 40 µ thickness were prepared from the center of the window, and the depth of carious lesion was measured in three points with 500 µ distance from each other using polarized light microscope. Data were analyzed using Statistical Package for the Social Sciences (SPSS) version 16 and nonparametric Kruskal-Wallis and Mann-Whitney U tests (α = 0.05). Results:The mean (and standard deviation) depth of carious lesion was 54.30 ± 28.64 (µm), 0, and 0 in groups I, II, and III respectively. Control group showed the highest depth of caries. Groups II and III were not significantly different in this respect, but significant differences were noted in depth of caries between groups I and II and also groups I and III (p < 0.001). Clinical significance: Application of green tea varnish can prevent root caries. Conclusion

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“…This comprises antioxidant, antibacterial, antiviral, anti-allergic, anti-colitis, anti-inflammatory, anti-arthritic and anti-cancer activities [21][22][23][24][25] . Among several polyphenol sources in the human diet, tea is one of the most consumed beverages around the world as a result of the pleasant taste, attractive aroma and health-promoting effects.…”

Section: Health Benefits Of Tea Polyphenols As Dietary Natural Productsmentioning

confidence: 99%

Tea Polyphenols as Natural Products for Potential Future Management of HIV Infection - an overview

Sodagari

Bahramsoltani

Farzaei

et al. 2016

JNR

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Belonging to the Lentivirus genus of animal retroviruses, human immunodeficiency virus (HIV) is the etiological agent of acquired immunodeficiency syndrome (AIDS) which attacks cells of the immune system including CD4+ T lymphocytes, monocytes, macrophages and dendritic cells. A rapid progression to immunodeficiency and the higher transmissibility of HIV-1 compared to HIV-2 are hallmarks of the worldwide spread of AIDS. Conventional HIV treatments are limited by drug toxicity and by multi-drug resistance, caused by the high genetic variability of HIV. This has led researchers into new areas of drug discovery in search of novel therapeutic molecules. Accumulating evidence indicates that tea polyphenols possess a range of beneficial properties including anti-cancer, anti-inflammatory, anti-oxidative, neuro-protective, anti-bacterial, anti-fungal and anti-viral effects. The anti-HIV infection potential of tea polyphenols has been confirmed by several preclinical studies. This suggests that polyphenol-rich extracts of tea could be used as dietary supplements as part of a combined therapeutic regimen with conventional anti-HIV drugs. Phenolic structures may also be considered as backbones for the discovery of a new generation of anti-HIV remedies. This review provides a perspective on the anti-HIV activity of tea polyphenols and their development as a possible source of future drugs for the therapy of HIV/AIDS.

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Antimicrobial Properties of Green Tea Extract Against Cariogenic Microflora: An In Vivo Study

Cited by 91 publications

References 20 publications

Inhibitory activity of a green and black tea blend on Streptococcus mutans

Inhibitory activity of a green and black tea blend on Streptococcus mutans

Effect of Green Tea Varnish on Depth of Root Caries

Tea Polyphenols as Natural Products for Potential Future Management of HIV Infection - an overview

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