Antimicrobial Properties of Strychnos phaeotricha (Loganiaceae) Liana Bark Secondary Metabolites at the Interface of Nanosilver Particles and Nanoencapsulation by Chitosan Transport Vehicles

Abstract

In this study, Strychnos phaeotricha liana bark extract was used as a metabolite container both on the surface of metallic nanosilver and encapsulated by a chitosan polymer. The plant extract was able to reduce Ag+ into Ag0 efficiently, and the encapsulation rate was determined. The synthesized nanoderivatives were characterized using ultraviolet-visible spectrophotometry (UV-Vis), Fourier transform infrared (FTIR) spectroscopy, powder X-ray diffraction (PXRD), scanning electron microscopy (SEM), and energy dispersive X-ray (EDX) spectroscopy. These methods allowed for the determination of grain size, elemental mapping, form, and the presence of secondary metabolites at the interface of the silver. Antimicrobial properties and the oral acute toxicity profile of the generated nanoderivatives were assessed. Overall, the results show plasmon resonance bands 380–550 nm in range and metabolites at the interface of a spherical nanosilver grain of 13.5 nm diameter in size. The hybrid nanosilver and encapsulated chitosan exhibited significant antimicrobial activity against Salmonella spp, Echerichia coli, and Candida spp. Both nanosilver grains and nanocapsules were found to be nontoxic at the tested doses and are potential models to prevent microbial resistance.

Magnesium hydroxide nanoneedles derived fromAnthocleista schweinfurthiiGilg (Loganiaceae) support mesenchymal stromal cell proliferation and wound healing

“…The nanoparticle synthesis required an aqueous extract. Our measurement of 6.8% extractable content for Anthocleista schweinfurthii is comparable to that reported by Tchangou et al, 6.9%, on Stryvhnos phaeotricha , a plant of the same family [37]. Phytochemical screening of AS revealed secondary metabolites such as alkaloids, flavonoids, coumarins, tannins, saponins and phenols, and the absence of terpenes, anthocyanins and anthraquinones.…”

“…6.9%, on Stryvhnos phaeotricha, a plant of the same family [37]. Phytochemical screening of AS revealed secondary metabolites such as alkaloids, flavonoids, coumarins, tannins, saponins and phenols, and the absence of terpenes, anthocyanins and anthraquinones.…”

Anti-inflammation Study of Cellulose-Chitosan Biocomposite-Based Tetrapleura tetraptera (Taub) Dried Fruits Aqueous Extract

“…2). Materials obtained by a mixture of chitosan and cellulose have presented transitions between 205-245 nm and shoulders between 300-450 nm [25]. This is in good agreement with the present results.…”

“…A study by powder X-ray diffraction of the extract with cellulose-chitosan material proves the presence of both polymers and shows that the mixture is composed of amorphous and crystalline regions [25]. As shown in the diffractogram (Fig.…”

“…The cellulose-chitosan biocomposite size of 53 nm is inside the range of other chitosan hybrid materials (46-58 nm) obtained using Eucalyptus oils [34]. Maxima of PXRD peaks were found to be varied with increasing content of chitosan in blended lms or by material grinding using a planetary ball mill [25,35].…”