Antimicrobial resistance among commensal Escherichia coli from cattle faeces and beef in Ibadan, Nigeria

Amosun, Elizabeth A.

doi:10.5897/ajb12.1646

Cited by 6 publications

(3 citation statements)

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“…These drugs are widely used in animal production in Nigeria and are readily available over the counter [29]. This study correlates with a study carried out by Amosun [29] which showed high resistance of over 70% to amoxicillin, ampicillin and streptomycin among EHEC O157:H7 isolates [30]. Over the years, antimicrobial resistance has increased and the normal intestinal microbial flora of humans have become a reservoir for resistant genes.…”

Section: Discussionsupporting

confidence: 82%

“…Enterohemorrhagic Escherichia coli O157 is a major pathogenic microorganism that frequently have been closely associated with foods of animal origin [2]. This pathogen in Humans causes asymptomatic infection to severe diarrhea and/or hemolytic-uremic syndrome (HUS) [30]. Human infections with EHEC O157 have been mostly linked with the consumption of improperly cooked or contaminated beef and unpasteurized cow milk [4].…”

Section: Introductionmentioning

confidence: 99%

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Antimicrobial Susceptibility Pattern of Enterohaemorrhagic Escherichia coli (EHEC O157:H7) in Raw Beef samples collected from abattoirs and Meat Vendors in Ile Ife and its environs, South-West, Nigeria

Dunah,

Oluwanifemi,

Aanuoluwa

2022

American J Pathol Res

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Nigeria bears a large burden of foodborne diseases in Africa, and the second leading causes of premature deaths in Africa is linked to diarrheal diseases. Enterohemorrhagic Escherichia coli O157 (EHEC O157:H7) causes an asymptomatic infection to severe diarrhea and/or hemolytic-uremic syndrome in humans which are serious health conditions that calls for serious health concern. The present investigation was done to study the prevalence and antibiotic resistance of Enterohaemorrhagic Escherichia coli O157:H7 strains isolated from raw meat samples. Raw beef samples were collected from abattoirs and retail outlets in three local government areas (LGAs) in Ile- Ife axis namely: Ife North, Ife Central and Ife East for isolation and identification of EHEC O157:H7. Standard microbiological methods were used to isolate and identify EHEC O157:H7 and antibiotics susceptibility pattern was carried out on the isolates to determine their susceptibility or otherwise. EHEC O157 was detected in 16% of meat samples from Abbatoirs slabs and 33% from meat vendors and retailers. EHEC O157 was not detected in one of the beef samples obtained from a particular Abbatoir. The EHEC O157:H7 isolates were found to be most susceptible to meropenem (91.50%) followed by vancomycin (90.80%) and ceftazidime (88.8%). Isolates were found to be most resistant to ampicillin (90.85%), followed by chloramphenicol (86.93%) and cefixime (85.63%). Furthermore, isolates were resistant to a range of more than five antibiotics and three classes of antibiotics, depicting multi drug resistance pattern. Five isolates were resistant to ampicillin, two isolates to streptomycin and three isolates to chloramphenicol. One isolate was resistant to two drugs and another to three drugs. The present study shows a bit higher prevalence of EHEC O157 in beef sold directly at abattoirs. Considering, the high infective dose of this pathogen and the deep-rooted tradition of consuming raw or undercooked beef, the current prevalence should not be considered lightly from a public health perspective.

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Section: Discussionsupporting

confidence: 82%

Section: Introductionmentioning

confidence: 99%

Antimicrobial Susceptibility Pattern of Enterohaemorrhagic Escherichia coli (EHEC O157:H7) in Raw Beef samples collected from abattoirs and Meat Vendors in Ile Ife and its environs, South-West, Nigeria

Dunah,

Oluwanifemi,

Aanuoluwa

2022

American J Pathol Res

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“…All of these abuses have been linked to an increase in antibiotic-resistant bacteria. More studies have found that non-compliance with antibiotic withdrawal periods is the leading cause of antibiotic drug residues in foods of animal origin 45 – 49 .…”

Section: Discussionmentioning

confidence: 99%

Knowledge, attitudes and practices of animal farm owners/workers on antibiotic use and resistance in Amhara region, north western Ethiopia

Geta

Kibret

2021

Sci Rep

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Inappropriate use of antibiotics in animal and human plays a role in the emergence and spread of bacteria resistant to antibiotics which threatens human health significantly. Although extensive use of these antibiotics could contribute to the development of drug resistance, information on the knowledge, attitude and practice of antimicrobial resistance and use among animal farm owners/workers in north western Ethiopia is rare. The objective of the present study was to assess knowledge, attitude and practice of animal farm owner/workers towards antibiotic resistance and use in Amhara regional state north western Ethiopia. A cross sectional study was conducted in selected cities of Amhara regional state from January to February, 2020. Data was collected from 91 participants using structured questionnaire and analyzed using SPSSS version 23. The results showed that 96.7% of respondents gave antibiotics to treat their livestock from different sources. Most of the respondents bought their antibiotics from private pharmacies without prescription and the most frequently mentioned antibiotics used to treat animal diseases was tetracycline (76.9%), followed by ampicillin (72.5%). Although, 90.1% of the animal farm owners heard about antibiotics and antibiotic resistance from different sources, they did not know the factors contributing to the transmission of resistant bacteria to humans and the impact of antibiotic resistance on human and animals’ health. Using the mean score 4.44 ± 0.15 as the cut-off, half of the animal farm owners/workers had good knowledge about antimicrobial resistance and use. 52.5% of animal farm owners/workers had positive attitudes towards wise antibiotic use and resistance with a mean score of 28.4 ± 0.5. However, 52.75% participants had poor practice with the mean score of practice 4.95 ± 0.17. Better knowledge, positive attitudes and better practices on antibiotic use and resistance were associated with farm owners/workers who engaged in higher education. Although poor awareness on antimicrobial resistance was perceived by 76.9% of respondents as very important factors that contribute to increasing antibiotic resistance, increasing the use of complementary treatments was perceived by the majority of respondents as very important strategies that contribute to reduce antibiotic use and resistance. The current study disclosed that there is low level of awareness among animal farm owners about the correct use of antibiotics and resistance. It is necessary to raise awareness, develop and implement interventions to reduce antimicrobial use and antibiotic resistance in the study area.

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Antimicrobial usage and presence of extended-spectrum β-lactamase-producing Enterobacteriaceae in animal-rearing households of selected rural and peri-urban communities

Okpara

Ojo

Awoyomi

et al. 2018

Veterinary Microbiology

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Antimicrobial resistance among commensal Escherichia coli from cattle faeces and beef in Ibadan, Nigeria

Cited by 6 publications

References 0 publications

Antimicrobial Susceptibility Pattern of Enterohaemorrhagic Escherichia coli (EHEC O157:H7) in Raw Beef samples collected from abattoirs and Meat Vendors in Ile Ife and its environs, South-West, Nigeria

Antimicrobial Susceptibility Pattern of Enterohaemorrhagic Escherichia coli (EHEC O157:H7) in Raw Beef samples collected from abattoirs and Meat Vendors in Ile Ife and its environs, South-West, Nigeria

Knowledge, attitudes and practices of animal farm owners/workers on antibiotic use and resistance in Amhara region, north western Ethiopia

Antimicrobial usage and presence of extended-spectrum β-lactamase-producing Enterobacteriaceae in animal-rearing households of selected rural and peri-urban communities

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