Antimicrobial resistance and prevalence of tetracycline resistance genes in Escherichia coli isolated from lesions of colibacillosis in broiler chickens in Sistan, Iran

Abstract

Background: Antibiotics have long been the first line of defense to prevent Escherichia coli infections, but they have lost their potency since bacteria have grown increasingly resistant to treatment. The present research aimed to study the drug resistance and the prevalence of tetracycline resistance genes in E. coli isolated from broilers with colibacillosis. Results: The results showed that the most prevalent type of drug resistance was to tetracycline at 95.0%, and the least was to gentamicin at 21.7%. The prevalences of antimicrobial resistance among the tested antibiotics were significantly different (p < 0.001). A statistically significant difference was observed between the prevalence of the tet genes (p < 0.001). The tetD positive isolates and antibiotic sensitivity to tetracycline showed statistical significant differences (p = 0.017). Conclusions: Considering the results, tetA is the most common tetracycline resistance gene, and the presence of tetD and antibiotic sensitivity to tetracycline had a significant relationship in E. coli isolated from colibacillosis infections.

Evaluation of Antibiotic Resistance Pattern of Escherichia coli Isolated From Broiler Chickens With Colibacillosis in Ardabil Province, Iran

“…31 This is very serious in Iran and other developing countries, which do not abide the use of antibiotics and avoid consumption of meat and other animal products treated with antibiotics. The present study findings (that the isolates were resistant to more than three type of antibiotic) is consistent with the study Jahantigh et al 22 of Saidi et al 16 In the present study, the frequency of drug resistance of isolates belonging to a single poultry unit was varied.…”

“…Neomycin (5.9%), sulfamethoxazole (4.5%), enrofloxacin (0.3%), ampicillin (2.9%) and erythromycin (1.5%) were observed. Jahantigh et al 22 In Sistan and Baluchestan province had the highest resistance of E. coli isolated from broiler herds with infected with colibacillosis against tetracycline (95.0%) and ciprofloxacin (88.3%), co-trimoxazole (86.7%) , lincospectin (52.5%) and gentamicin (21.7%) and also the prevalence of tetA, tetB, tetC and tetD genes of tetracycline resistance among 60 isolates were 96.7%, 38.3%,7.731% and 8.30%, respectively. Bakhshi et al 23 In Yazd also reported the highest resistance to nalidixic acid (100%) and ciprofloxacin (86%) and the highest sensitivity to colistin (100%) and gentamicin (93%).…”

Virulence and Antimicrobial Resistance Profiles of Salmonella enterica Serovars Isolated from Chicken at Wet Markets in Dhaka, Bangladesh

“…Arkali and Çetinkaya [72] detected sul1 gene with 58% among the Salmonella isolates from chickens in eastern Turkey. Consequently, Jahantigh et al [101] isolated the most prevalent tetA from broiler chicken in Iran. Accordingly, Vuthy et al [89] detected blaTEM, tetA, strA/B gene from chicken food chain while Sin et al [102] isolated tetA and sul1 gene from chicken meat in Korea.…”

Virulence and antimicrobial resistance profile of non-typhoidalSalmonella entericaserovars recovered from poultry processing environments at wet markets in Dhaka, Bangladesh

“…Consequently,Jahantigh et al (2020) detected the most prevalent tetA gene from broiler chicken in Iran. Successively,Vuthy et al (2017) discovered blaTEM, tetA and strA/B gene from chicken food chain whileSin et al (2020) isolated tetA and sul1 gene from chicken meat in Korea Zhu et al (2017).…”