Antimicrobial Resistance Phenotypes of ETEC Isolates from Piglets with Diarrhea in North Vietnam

Do, N.T.; Cu, Huang; Nguyen, N.N.; Nguyen, X.H.; Au, X.T.; Van, T.H.; Vu, Nicolas; Trott, Darren J.

doi:10.1196/annals.1373.082

Cited by 10 publications

(6 citation statements)

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“…These two drugs are commonly used for treating urogenital infections in Vietnam. The resistance pattern resembles that reported in two other Vietnamese studies focusing on community-acquired pneumonia and agricultural animals [ 30 , 31 ]. One explanation for the observed resistance towards ampicillin and sulphametoxazol with trimethoprim is that these two types of antibiotics, in contrast to cephalosporins, quinolones and aminoglycocides, which had all retained their activity, are often bought over the counter without any prescription [ 30 ].…”

Section: Discussionsupporting

confidence: 83%

Reproductive tract infections in women seeking abortion in Vietnam

Huong

Kurtzhals

Thủy³

et al. 2009

BMC Women's Health

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BackgroundWomen requesting abortion are at increased risk of developing RTI complications. However, RTI control in many resource-poor countries including Vietnam have been faced with logistical and methodological problems due to lack of standardized definitions of RTIs, lack of well-validated diagnostic criteria, lack of accurate laboratory tests, and lack of diagnostic equipment and skills. This article investigates the prevalence of RTIs among Vietnamese abortion-seeking women, to evaluate the available diagnostic techniques, and to assess antibiotic resistance among aetiological agents of RTI.MethodThe study was conducted in Phu-San hospital (PSH) from December 2003 through April 2004 among 748 abortion clients. A structured questionnaire was used to collect data on socio-economic and reproductive characteristics. Specimens were collected for laboratory analyses of chlamydia, gonorrhoea, trichomoniasis, vaginal candidiasis (VC), bacterial vaginosis (BV) and syphilis. To assess the validity of the obtained results, the study was repeated among 100 women and the duplicate samples were analysed at PSH and Copenhagen University Hospital (CUH).ResultsIn all 54% of the women were diagnosed as having an RTI, including 3.3% with sexually transmitted infections. Endogenous infections were most prevalent (VC 34% and BV 12%) followed by chlamydia (1.3%) and trichomoniasis (0.7%). The sensitivity of culture for VC and BV was 30% and 88%, respectively, when tests in PSH were measured against tests in CUH. Antibiotic resistance was common among bacterial isolates.ConclusionRTIs are common among women seeking abortion. The presence of RTIs is associated with an increased risk of developing iatrogenic infections, routine administration of prophylactic antibiotic to all women undergoing abortion should be considered. However, the choice of routine prophylactic antibiotics should be based on relevant surveillance data of antibiotic resistance. Moreover, since the accuracy of diagnosis is doubtful and to address the problem of under-diagnosed and treated RTIs new investment in diagnostic facilities with simple performed microscopy or improved rapid tests should also be taken into consideration.

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Section: Discussionsupporting

confidence: 83%

Reproductive tract infections in women seeking abortion in Vietnam

Huong

Kurtzhals

Thủy³

et al. 2009

BMC Women's Health

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“…The classical ETEC type implicated in postweaning diarrhea is characterized by the possession of the K88 CF, but recently, ETEC types possessing the F18 CF and other novel CFs have emerged as porcine pathogens. Complicating the control of this disease is a rapid increase in the percentage of multidrugresistant porcine ETEC strains, which is thought to be due to the extensive use of antibiotics as growth promoters and therapeutic agents (15,41,114). While vaccination strategies have been effective in preventing neonatal diarrhea, those aimed at protecting weaned pigs have had mixed results (49).…”

Section: Porcine Etec Plasmidsmentioning

confidence: 99%

Pathogenomics of the Virulence Plasmids ofEscherichia coli

Johnson

Nolan

2009

Microbiol Mol Biol Rev

376

369

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SUMMARY Bacterial plasmids are self-replicating, extrachromosomal elements that are key agents of change in microbial populations. They promote the dissemination of a variety of traits, including virulence, enhanced fitness, resistance to antimicrobial agents, and metabolism of rare substances. Escherichia coli, perhaps the most studied of microorganisms, has been found to possess a variety of plasmid types. Included among these are plasmids associated with virulence. Several types of E. coli virulence plasmids exist, including those essential for the virulence of enterotoxigenic E. coli, enteroinvasive E. coli, enteropathogenic E. coli, enterohemorrhagic E. coli, enteroaggregative E. coli, and extraintestinal pathogenic E. coli. Despite their diversity, these plasmids belong to a few plasmid backbones that present themselves in a conserved and syntenic manner. Thanks to some recent research, including sequence analysis of several representative plasmid genomes and molecular pathogenesis studies, the evolution of these virulence plasmids and the implications of their acquisition by E. coli are now better understood and appreciated. Here, work involving each of the E. coli virulence plasmid types is summarized, with the available plasmid genomic sequences for several E. coli pathotypes being compared in an effort to understand the evolution of these plasmid types and define their core and accessory components.

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“…It has high levels of antimicrobial use both in humans and animals and resistance among bacterial pathogens is widespread [1]. Use of antimicrobials in commercial pig production is largely unregulated and access to veterinary advice is limited.…”

Section: Page 5 Of 28mentioning

confidence: 99%

“…A total of 97 MDR-ETEC isolates (2001) were obtained from Vietnamese pig faecal samples as described previously [1]. Animals' symptoms were consistent with porcine colibacillosis.…”

Section: Bacterial Isolatesmentioning

confidence: 99%

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Comparison of antimicrobial resistance phenotypes and genotypes in enterotoxigenic Escherichia coli isolated from Australian and Vietnamese pigs

Smith

Gibson

et al. 2014

Journal of Global Antimicrobial Resistance

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This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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Antimicrobial Resistance Phenotypes of ETEC Isolates from Piglets with Diarrhea in North Vietnam

Cited by 10 publications

References 0 publications

Reproductive tract infections in women seeking abortion in Vietnam

Reproductive tract infections in women seeking abortion in Vietnam

Pathogenomics of the Virulence Plasmids ofEscherichia coli

Comparison of antimicrobial resistance phenotypes and genotypes in enterotoxigenic Escherichia coli isolated from Australian and Vietnamese pigs

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