Antimicrobial resistance profile of Streptococcus pneumoniae in children <5 years of age in sea nomads population in Indonesia

Abstract

none belonged to global epidemic clone ST258. Interestingly, IncL plasmid known to carry bla OXA48-like was absent in Indian isolates despite high rates of bla OXA48-like . Plasmid mediated colistin resistance is absent. There is threat of ST23 MDR hypervirulent Kp. High rate of colistin resistance is worrisome for management of these infections. Therapeutic options for Indian Kp are different from other regions due to prevalence of OXA48-like and NDM carbapenemases.

Characterization of MultidrugResistant serogroup 19 Streptococcus pneumoniae isolated from healthy children below 5 years of age in Indonesia

“…In total, 104 archived MDRSP serotypes 19F ( n =100) and 19A ( n =4) isolates were collected from previous nasopharyngeal carriage studies among healthy children below 5 years of age from different regions in Indonesia: Kotabaru, South Kalimantan [ 12 ] (2019: 40 isolates 25 isolates); Southwest Sumba, East Nusa Tenggara (2016: 28 isolates) and Gunung Kidul, Yogyakarta (2016: 40 isolates) ([ 13 ], under review); and Wakatobi, Southeast Sulawesi (2018: 11 isolates) ([ 14 ], under review). The data for S. pneumoniae isolates can be seen in Table S1.…”