Antimicrobial Resistance Profiles and Mechanisms of Resistance in<i>Campylobacter jejuni</i>Isolates from Pets

Acke, Els; McGill, Kevina; Quinn, Teresa; Jones, B. R.; Fanning, Séamus; Whyte, Paul

doi:10.1089/fpd.2008.0225

Cited by 14 publications

(11 citation statements)

References 41 publications

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“…In C. coli, a lower level of resistance was observed in the isolates from dogs. Frequency of ampicillin resistance of C. jejuni from dogs and humans in this study are similar with the previous reports [1,32]. C. jejuni isolates from humans showed higher resistance to ampicillin than those isolated from dogs (p ≤ 0.05).…”

Section: Discussionsupporting

confidence: 92%

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Characterization of antimicrobial resistance and application of RFLP for epidemiological monitoring of thermophilic Campylobacter spp. isolated from dogs and humans in Korea

Cho¹,

Kim²,

Min³

et al. 2014

Korean Journal of Veterinary Research

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: An antimicrobial susceptibility test was conducted to compare the resistance rates among Campylobacter spp. isolates from dogs (n = 50) raised under diverse conditions and humans (n = 50). More than 60% of Campylobacter (C.) jejuni from dogs and humans showed resistance to nalidixic acid, enrofloxacin and ciprofloxacin. C. jejuni isolates from humans showed higher resistance to tetracycline (83.3%) and ampicillin (91.3%) than those from dogs. None of the C. jejuni or Campylobacter coli isolates from humans or dogs were resistant to erythromycin. Overall, 85% of Campylobacter spp. isolates showed a multidrug resistant phenotype. Nucleotide sequencing analysis of the gryA gene showed that 100% of NA R /CIP R C. jejuni isolates from dogs and humans had the Thr-86 t h -Ile mutation, which is associated with fluoroquinolone resistance. flaA PCR restriction fragment length polymorphism (RFLP) typing to differentiate the isolates below the species level revealed 12 different clusters out of 73 strains. The human isolates belonged to eight different RFLP clusters, while five clusters contained dog and human isolates.

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Section: Discussionsupporting

confidence: 92%

“…The household dog has previously been identified as a risk factor for human campylobacteriosis [1,3,29]. Most of dogs carrying the bacteria are asymptomatic, serving as reservoirs capable of shedding Campylobacter spp.…”

Section: Introductionmentioning

confidence: 99%

Characterization of antimicrobial resistance and application of RFLP for epidemiological monitoring of thermophilic Campylobacter spp. isolated from dogs and humans in Korea

Cho¹,

Kim²,

Min³

et al. 2014

Korean Journal of Veterinary Research

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“…In Ireland, Acke et al . (2009c) found with E‐test the following rates of resistance: 37.3% nalidixic acid, 19.6% ciprofloxacin, 13.7% tetracycline, 13.7% ampicillin, 11.8% erythromycin (ERY). In Poland, Andrzejewska et al .…”

Section: Discussionmentioning

confidence: 99%

Prevalence of most common human pathogenicCampylobacterspp. in dogs and cats in Styria, Austria

Pölzler

Stüger

Lassnig

2018

Veterinary Medicine & Sci

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The aim of this study was to determine the frequency of occurrence of most common human pathogenic Campylobacter species, Campylobacter jejuni (C. jejuni) and Campylobacter coli (C. coli), in dogs and cats in Styria, Austria. In the period from April 2010 to April 2012, 842 faecal samples from dogs and cats from Styria, Austria were examined for Campylobacter (C.) species (spp.). All samples were subjected to qualitative microbiological culture testing, and additionally, some of them have been studied using qualitative real‐time PCR. In microbiological culture, 5.9% of all samples investigated were C. spp. positive. With 3.1% out of positive samples, C. jejuni was the most common type. Campylobacter upsaliensis (C. upsaliensis) was detected only in 0.5% of the samples. The remaining positive samples (2.4%) were classified as C. species (sp.). C. coli could not be found in any of the samples. A higher prevalence of C. jejuni was found in kittens with 14.3% and in diarrhoeic dogs (7.4%) and cats (23.8%). The real‐time PCR revealed for dogs and cats together, 27% of C. jejuni‐positive faecal and 8% positive faecal swap samples. The obtained C. jejuni strains underwent antibiotic resistance testing using three different tests (agar diffusion, MIC testing and E‐test) with different numbers of antibiotics. From the antibiotics used in this study, several showed high test‐dependent resistance rates (cephalexin, cefovecin, kanamycin, sulfamethoxazole/trimethoprim, penicillin G, ciprofloxacin, enrofloxacin, marbofloxacin, nalidixic acid). Overall, the prevalence of C. spp. in this study was very low compared to others, with the exception of C. jejuni in kittens and diarrhoeic animals. The results of the real‐time PCR suggest that the rate of colonization of C. jejuni was actually higher than the results of the culture showed. As the resistance rates of C. jejuni isolates partly were very high, possible transmission of (multi‐) resistant C. jejuni strains to humans especially from kittens and diarrhoeic animals must be expected.

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“…Resistance to quinolones and ciprofloxacin has been documented (Acke et al, 2009). Erythromycin, neomycin, enrofloxacin, clindamycin, and doxycycline are all effective.…”

Section: Laboratory Animal Medicinementioning

confidence: 99%

Biology and Diseases of Dogs

Nemzek

Lester

Wolfe

et al. 2015

Laboratory Animal Medicine

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Antimicrobial Resistance Profiles and Mechanisms of Resistance inCampylobacter jejuniIsolates from Pets

Cited by 14 publications

References 41 publications

Characterization of antimicrobial resistance and application of RFLP for epidemiological monitoring of thermophilic Campylobacter spp. isolated from dogs and humans in Korea

Characterization of antimicrobial resistance and application of RFLP for epidemiological monitoring of thermophilic Campylobacter spp. isolated from dogs and humans in Korea

Prevalence of most common human pathogenicCampylobacterspp. in dogs and cats in Styria, Austria

Biology and Diseases of Dogs

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