Antimicrobial Sensitivity Profile Of Uropathogens In A Macapá Laboratory, Amapá, Brazilian Amazon

Abstract

Urinary tract infections (UTI) represent a worldwide health problem. Microbial resistance, due to selective antibiotic pressure, has a direct influence on the evolution and impact of these infections. The objective of this work was to identify the antimicrobial susceptibility profile of uropathogens isolated in uroculture samples from a private laboratory in the city of Macapá/AP. It is a quantitative, retrospective and cross-sectional study, using a laboratory database. Data were collected from results of urocultures with antibiogram analyzed from January to December 2019. The present study evaluated 3,510 urocultures, carried out during the study period, of which 1,269 had bacterial growth, equivalent to 36.15%. Among the positive results, we found the bacteria Escherichia coli (66.59%), Staphylococcus aureus (32.62%), mixed colonies of E. coli and S. aureus (0.47%), Staphylococcus saprophyticus (0.24%) and Serratia marcescens (0.08%). The male gender was responsible for 16.35% (n = 574) of the urocultures analyzed, while the female population was 83.65% (n = 2936). When analyzing the distribution of bacteria isolated by gender, males were considered a protective factor with 42% less chance of presenting bacteria in urine. The bacteria E. coli was the predominant pathogen in these infections in both sexes and in all age groups.