Antimicrobial susceptibility pattern of <i>Aeromonas hydrophila</i> among patients presented with diarrhea attending two teaching hospitals in northern, Nigeria

Abstract

A total of one hundred and twenty eight (128) stool samples were collected from patients attending Ahmadu Bello University Teaching Hospital Zaria and Aminu Kano Teaching Hospital Kano, and screened for the presence of Aeromonas hydrophila infection. Out of the one hundred and twenty eight samples analyzed 4 (3.12%) were found positive for Aeromonas hydrophila infection. Antibioticsusceptibility testing of Aeromonas hydrophila isolated showed that all the 4 (100%) isolates were sensitive to Colistin and Ceftazidime, 3 (75%) to Augmentin and 2(50%) to Gentamicin and Cefuroxine. All the isolates (100%) were however resistant to Cotrimoxazole, Tetracycline, Sulphatriad, Streptomycin, Cephalothin and Ampicilin. This study confirmed that Aeromonas hydrophila as a sole enteropathogen could be responsible for diarrhea and should be considered amongst the causative agents of diarrhea.

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“…This is consistent with some previous studies [30][31]. However, in contrast to Rogo et al [25] who reported only a few species were resistance to Augmentin in their study, although, Imipenem has been reported to be effective for treatment of Aeromonas infection [32], in the present study all the isolates were resistant to Imipenem. Four isolates of A. hydrophila in this study were resistant to cefazolin and gentamycin but susceptible to ciprofloxacin and tetracycline.…”

“…In this study, Aeromonas hydrophila was the only species isolated and is from the diarrheic stool samples. Several studies have shown a similar preponderance of the species [22][23][24][25]. The prevalence rate of 3.5% from diarrheic stool samples in the present study is consistent with that of Rogo et al [25] who reported a prevalence of 3.12% in 128 patients attending Ahmadu Bello University Teaching Hospital (ABUZTH) and Aminu Kano Teaching Hospital (AKTH) but less than the 13% reported by Nzeakor and Okafor [26] in Nigeria and 12.8% reported by Samie et al [27] in South Africa.…”

“…Several studies have shown a similar preponderance of the species [22][23][24][25]. The prevalence rate of 3.5% from diarrheic stool samples in the present study is consistent with that of Rogo et al [25] who reported a prevalence of 3.12% in 128 patients attending Ahmadu Bello University Teaching Hospital (ABUZTH) and Aminu Kano Teaching Hospital (AKTH) but less than the 13% reported by Nzeakor and Okafor [26] in Nigeria and 12.8% reported by Samie et al [27] in South Africa. Differences in the prevalence rate of Aeromonas species from countries or regions have been attributed to differences in the sampling period, geographical location, origin of samples and methodology for analysis [28].…”

“…Four isolates of A. hydrophila in this study were resistant to cefazolin and gentamycin but susceptible to ciprofloxacin and tetracycline. Resistance to commonly used antibiotics has been attributed to subtherapeutic and extensive usage of these antibiotics [25]. The limitation of this study is that stool samples positive for Aeromonas species were not tested for the presence of other enteric bacteria.…”

Isolation and Application of Pathogenic and Biological Control Bacteria from Pupae of Golden Silkworm Cricula trifenestrata Helfer

“…Aeromonas dhakensis is pathogenic in fish (Soto Rodriguez et al, 2013) and human (Rogo et al, 2009). Aeromonas are responsible for ulcerative disease outbreaks in Mtera Dam (Shayo et al, 2012).…”