Antimicrobials in the management of invasive meningococcal disease

Lennon, Diana

doi:10.1046/j.1440-1754.2001.00626.x

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Cited by 2 publications

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“…All children in the region with a serious illness are admitted to one or other The length of treatment in all forms of bacterial meningitis has been the subject of much debate. 1 Recommendations have been based on consensus and experience rather than robust data. Meningococcal meningitis (MM), for example, has been treated for anywhere from 1 to 14 days.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Rapid sterilisation of cerebrospinal fluid in meningococcal meningitis: Implications for treatment duration

Crosswell

Nicholson²,

Lennon

2006

J Paediatrics Child Health

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Section: Methodsmentioning

confidence: 99%

“…The length of treatment in all forms of bacterial meningitis has been the subject of much debate 1 . Recommendations have been based on consensus and experience rather than robust data.…”

mentioning

confidence: 99%

Rapid sterilisation of cerebrospinal fluid in meningococcal meningitis: Implications for treatment duration

Crosswell

Nicholson²,

Lennon

2006

J Paediatrics Child Health

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Antibiotic treatment for bacterial meningitis in children in developing countries

Fuller

Duke

Shann

et al. 2003

Annals of Tropical Paediatrics

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Bacterial meningitis causes 125,000 deaths each year in infants and young children and 96% of these occur in less developed countries where up to 50% of children with this disease die and 25-50% of survivors have neurological sequelae. Although 3rd-generation cephalosporins are optimal empirical therapy for bacterial meningitis, they are unaffordable in many developing countries. The majority of children worldwide are currently treated with cheaper alternatives. This paper reviews the challenges facing clinicians treating bacterial meningitis in developing countries, highlighting the problem of changing patterns of antibiotic resistance. In particular, it details the evidence for the use of chloramphenicol and 3rd-generation cephalosporins.

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Antimicrobials in the management of invasive meningococcal disease

Cited by 2 publications

References 28 publications

Rapid sterilisation of cerebrospinal fluid in meningococcal meningitis: Implications for treatment duration

Rapid sterilisation of cerebrospinal fluid in meningococcal meningitis: Implications for treatment duration

Antibiotic treatment for bacterial meningitis in children in developing countries

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