Antimüllerian hormone as predictor of implantation and clinical pregnancy after assisted conception: a systematic review and meta-analysis

Use of anti-mullerian hormone for testing ovarian reserve: a survey of 796 infertility clinics worldwide

“…In several series, AMH levels are associated with live births [18,23]; however, in others, no association was identified [24]. In a recent 2015 meta-analysis conducted by Tal et al, 19 studies were analyzed by specific subpopulations comparing the predictive value of AMH with implantation and pregnancy rates, and they concluded that AMH has some association, but its predictive value is weak [25]. In another recent meta-analysis, which included 13 studies, they also conclude that AMH does have some association with predicting live birth; however, its predictive accuracy is poor with low calculated diagnostic odds ratios [26].…”

Antimullerian hormone levels are inversely associated with body mass index (BMI) in women with polycystic ovary syndrome

“…Recently, AMH has emerged as a promising marker of ovarian reserve and even as a predictor of in vitro fertilization (IVF) success [5]. In a systematic review and meta-analysis by Tal [6], AMH has been shown to be associated with implantation and, albeit weakly, clinical pregnancy. As an effective marker of ovarian reserve AMH has the advantage that, unlike FSH and other hormones produced by the ovary, it does not significantly change during the menstrual cycle.…”

Personalized prediction of live birth: Are we there yet?

“…One possible explanation for the discrepant findings may be the different outcome studied (i.e., ongoing pregnancy rate vs. live birth), with the small association between AMH and live birth becoming apparent only after noncontinuing pregnancies are lost. Moreover, the current study by Nelson et al evaluated cumulative live birth rate, examining the pregnancy rate resulting from all embryo transfers linked to the same single fresh cycle, whereas the included studies in the 3 meta-analyses mostly evaluated pregnancy or live birth rate per fresh cycle (2)(3)(4). This suggests that AMH may be a better predictor of a woman's total reproductive potential, compared with the outcome of a specific embryo transfer.…”