Antioxidant Activities of Ethanolic and Aqueous Extracts of Asparagus racemosus Roots

Abstract

Asparagus racemosus (AR) wild., (Family: Liliaceae), commonly known as shatavari, satawar or satmuli, is found in all over India, and is commonly known in Thailand as sam-sib or rak-sam-sib. In Ayurveda, the dried root of AR is used as a tonic, galactogogue, aphrodisiac, rejuvenator, antispasmodic, antiulcerous and anti-inflammatory agent. Steroidal saponins and sapogeninsare the pharmacological value of the AR root. 1-2 Antioxytocic activities, antihepatotoxic, hepatopathy, dyspepsia and dysentery are the uses of the root of AR for treatment. 1 Recent reports on AR indicate that the root extracts show antioxidant and antidiarrheal activities in animal models. 3-4 Phytoanalysis of the AR root composition by Visavadiya et al. 5 found phytosterols 0.79%, saponins 8.83%, polyphenols 1.69%, flavonoids 0.47% and total ascorbic acid 0.76%. AR contains alkaloids, flavonoids, tannins, saponins, phenols, terpenes, polysaccharides and steroids. 5 AR root extract was found to contain flavonoids, polyphenols and vitamin C, which were found to exhibit the greatest antioxidant activity. A phytoestrogenic effect of AR root extracts has recently been found as well as antidiarrhoeal, antidyspepsia, adaptogenic, cardioprotective, antibacterial, immune adjuvant and antitussive effects. The methanolic and aqueous extracts of AR roots have been produced in Antioxidant Activities of Ethanolic and Aqueous Extracts of Asparagus racemosus Roots Background: Asparagus racemosus (AR) is commonly known as shatavari, satawar or satmuli in India and in Thailand it is call sam-sib or rak-sam-sib. The dried root of AR is used in Ayurveda as an antiulcerous and antiinflammatory and has medicinal/pharmacological value. Objective: To investigate the antioxidant activities of Asparagus racemosus root extracts via total phenolic and total flavonoid contents of ethanolic and aqueous extracts. Methods: Antioxidant capacity measurements were carried out by DPPH, ABTS and FRAP methods. Total phenolic and flavonoid contents were determined by the Folin-Ciocalteu method and the aluminum chloride colorimetric method, respectively. Results: The ethanolic extract possessed higher antioxidant capacities than the aqueous extract in the three antioxidant assays (p<0.05).These results have shown high phenolic and flavonoid contents. The ethanolic extract of AR root possessed higher amounts of phenolic and flavonoid contents than the aqueous extract. Conclusion: The antioxidant capacity of the ethanolic extract was higher than that in the aqueous extract. .

De novo sequencing, assembly, and characterization of Asparagus racemosus transcriptome and analysis of expression profile of genes involved in the flavonoid biosynthesis pathway

“…Secondary metabolites such as quercetin, rutin, and kaempferol are the mainly reported flavonoid components in A. racemosus . They have numerous therapeutic activities, including anti oxidative action ( Taepongsorat and Rattana, 2018 ), anti-inflammatory, antitumor effects ( Mitra et al, 2012 ), and antimicrobial activities ( Aggarwal et al, 2013 ). Flavonoids, a class of phenylpropanoids widely distributed in the plant kingdom, comprise one of the major secondary metabolite groups with a C6-C3-C6 general structural backbone.…”