Antioxidant activity and identification of bioactive compounds from leaves of Anthocephalus cadamba by ultra–performance liquid chromatography/electrospray ionization quadrupole time of flight mass spectrometry

Chandel, Madhu; Sharma, Upendra; Kumar, Neeraj; Singh, Bikram; Kaur, Satwinderjeet

doi:10.1016/s1995-7645(12)60186-2

Cited by 32 publications

(18 citation statements)

References 55 publications

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“…Nitric oxide reacts with free radicals, thereby producing the highly damaging peroxynitrite. Nitric oxide injury takes place for the most part through the peroxynitrite route because peroxynitrite can directly oxidize LDLs, resulting in irreversible damage to the cell membrane [19][20][21][22][23][24][25] . Hence, various extract from L. camara could be used to overcome various health problem causes by nitric oxide injury.…”

Section: Discussionmentioning

confidence: 99%

Antioxidant activity of methanol extracts of different parts of Lantana camara

Mahdi-Pour

Jothy

Latha

et al. 2012

Asian Pacific Journal of Tropical Biomedicine

188

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Section: Discussionmentioning

confidence: 99%

Antioxidant activity of methanol extracts of different parts of Lantana camara

Mahdi-Pour

Jothy

Latha

et al. 2012

Asian Pacific Journal of Tropical Biomedicine

188

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“…Hydroxyl radical, the most active and toxic free radical, can attack and damage almost every bio-macromolecule in living cells. Hydroxyl ions are formed through the redox reaction between metal ions and peroxide, whose biological damage is its capacity to stimulate lipid peroxidation, which occurs when hydroxyl radical is generated close to membranes and attacks the fatty acid side chains of the membrane phospholipids (Urban et al, 1995;Chandel et al, 2012). 2,2-diphenyl-1-picrylhydrazyl radical is a stable, nitrogen-centered free radical that produces a violet color in ethanol solution.…”

Section: Discussionmentioning

confidence: 99%

Investigation of the antioxidant activity of chitooligosaccharides on mice with high-fat diet

Han

2016

R. Bras. Zootec.

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-The objective of this study was to analyze the antioxidant activities of chitooligosaccharides (COS) both in vitro and in high-fat diet (HFD)-mouse model. In antioxidant assays in HFD-mouse model, mice were administered with normal diet, HFD, or HFD with 0.5% COS for six weeks. The administration of HFD with 0.5% COS resulted in significant increase in the activity of superoxide dismutase, catalase, and glutathione peroxidase in stomach, liver, and serum of mice as compared with the HFD-fed group, which means that COS may have certain antioxidant activity and can restore the activity of the enzymes affected by the HFD. Through morphological measurements of the small intestinal mucosa, mice fed HFD showed decreased villus height compared with other groups. On the other hand, HFD with 0.5% COS group showed similar ratio of villus height to depth compared with control mice, indicating that intestinal integrity was improved when COS was added. Chitooligosaccharides have potent antioxidant activity that can protect mice from oxidative stress.

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“…Ethyl acetate and butanol fractions of Butea monosperma flowers were studied for free radical scavenging activity 14 and also evaluated for its sunscreen activity by absorption spectroscopy and transmission spectroscopy methods 15 . Ethanolic extract of Neolamarckia cadamba was studied for total phenolic content and antioxidant assay 16 , methanolic extract of cadama plant shown better DPPH radical scavenging activity 17 . Traditionally cadamba leaves were used to cure pimples and wounds, its different extracts are reported for their antimicrobial, anti-inflammatory properties 18 , Punica granatum fruit and peel extracts were reported for their antioxidant and anti-inflammatory property.…”

Section: Introductionmentioning

confidence: 99%

Formulation and in Vitro Evaluation of Antioxidant Activity of Herbal Sunscreen Formulation

Sutar¹,

Chaudhari²

2020

Int Res J Pharm

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UV radiations reaching to the surface of the earth are responsible to cause skin damage and condition get worse on long exposure. The chemical and physical sunblock agents are not enough to protect skin, whereas natural products are emerging on large scale for their health benefits. The present investigation is an attempt to formulate herbal sunscreen creams and their evaluation for total phenolic, flavonoid content and free radical scavenging property. Flowers of Butea monosperma, leaves of Neolamarckia cadamba, peel of Punica granatum and leaves of Cymbopogon citratus were extracted with methanol. Total five creams with concentration of 2% w/w were formulated in different combinations using 1:1 proportion of extracts. The total phenolic, flavonoid content and antioxidant potential was determined. Diphenyl picrylhydrazyl (DPPH), nitric oxide (NO) radical scavenging assays and reducing power assay were studied by using ascorbic acid as reference standard. The total phenolic and flavonoid content of F-5 was higher and found to be 38.76±0.59 mg GAE/g and 47.89±0.36 mg QE/g respectively. F-1 to F-5 creams exhibited antioxidant potential in concentration dependant manner. Cream F-5 shown better antioxidant property with IC50 value 22.97 μg/ml and 51.49 μg/ml for DPPH and NO respectively and increased reducing ability with higher absorbance. The mixture of all extracts indicating synergetic property of polyphenolic phytoconstituents present in F-5. Further the formulation is required to study for its in vitro and in vivo sun protective property.

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Antioxidant activity and identification of bioactive compounds from leaves of Anthocephalus cadamba by ultra–performance liquid chromatography/electrospray ionization quadrupole time of flight mass spectrometry

Abstract: The potential of the extract/fractions to scavenge different free radicals in different systems indicated that they may be useful therapeutic agents for treating radical-related pathologic damage.

Cited by 32 publications

References 55 publications

Antioxidant activity of methanol extracts of different parts of Lantana camara

Antioxidant activity of methanol extracts of different parts of Lantana camara

Investigation of the antioxidant activity of chitooligosaccharides on mice with high-fat diet

Formulation and in Vitro Evaluation of Antioxidant Activity of Herbal Sunscreen Formulation

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