Antioxidant activity, mutagenicity/anti-mutagenicity, and clastogenicity/anti-clastogenicity of lutein from marigold flowers

Wang, Mingchen; Tsao, Rong; Zhang, Shanfeng; Dong, Ziming; Yang, Raymond; Gong, Jianhua; Pei, Yingxin

doi:10.1016/j.fct.2006.04.005

Cited by 113 publications

(74 citation statements)

References 29 publications

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“…Carotenoids, which are fat-soluble pigments, mainly confer yellow, orange, and red colors to plants and play an important role in human nutrition as precursors of vitamin A and antioxidants, of which lutein and zeaxanthin are important for eye health and protect cells from carcinogens (Wang et al 2006). Only lutein and zeaxanthin were identified in the present study (Table 1).…”

Section: Carotenoid Flavonoid and Anthocyaninmentioning

confidence: 65%

Compositional Analysis of Lentil (Lens culinaris) Cultivars Related to Colors and Their Antioxidative Activity

Lee¹,

Yeo²,

Park³

et al. 2017

Plant Breed. Biotech.

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Metabolite profile is a powerful analytical technique to identify the functional characterization of plants. In this study, the phytochemicals and secondary metabolites of lentils (Lens culinaris) were analyzed to compare the anti-oxidative activities according to the different colors. The polar metabolites, fatty acids, carotenoids, flavonoids, anthocyanins, total phenolic acids, DPPH activity were analyzed. Three kind of lentils, French green whole lentil (FG), red whole lentil (LR), and green whole lentil (LG) (ASIA SEED Co., LTD), were used for this study. Fatty acids, phytochemicals, and antioxidative components from each lentil varieties were analyzed by official methods. The contents of lutein in carotenoids were 6-9 times higher than zeaxanthin in all lentils, but were not significantly different among three varieties. The content of carotenoids in FG was lower significantly than those in the LR and LG. Myricetin and luteolin were detected in the only FG. Kaempferol and delphinidin were significantly highest in the FG. Most of the phenolic acids except coumarate were higher in FG and LG than in LR. Also antioxidant effects (EC50) were higher in FG and LG than in LR. The analyzed metabolites obtained from lentils showed distinct separation in the PCA results according to the varieties. Also, lentils showed different anti-oxidant profiles according to the colors. FG and LG showing higher contents of phytochemicals showed higher antioxidative activity than LG containing relative low contents of phytochemicals.

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Section: Carotenoid Flavonoid and Anthocyaninmentioning

confidence: 65%

Compositional Analysis of Lentil (Lens culinaris) Cultivars Related to Colors and Their Antioxidative Activity

Lee¹,

Yeo²,

Park³

et al. 2017

Plant Breed. Biotech.

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show abstract

“…Some dietary antioxidants actively modulate endogenous antioxidant enzymes to remove excessive reactive oxygen species induced by oxidative stress (Chen et al, 1987). Carotenoids such as lutein are an effective chain-breaking antioxidant because of their ability to quench singlet oxygen and scavenge peroxy radicals (Wang et al, 2006). However, there is a lack of information on the effects of dietary lutein on endogenous antioxidant enzymes in laying hens, although numerous in vitro studies have demonstrated that lutein has shown beneficial effects on antioxidant defense system against free radicals (Bhattacharyya et al, 2010;Hayes et al, 2009;Li et al, 2007).…”

Section: Discussionmentioning

confidence: 99%

Effects of Dietary Lutein Sources on Lutein-Enriched Egg Production and Hepatic Antioxidant System in Laying Hens

Jang

Kang

et al. 2014

J. Poult. Sci.

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The present study was conducted to investigate the effects of two dietary lutein sources such as the commercial lutein and the emulsified crude extract of spinach containing lutein on the transfer of lutein into egg yolks as well as the antioxidant defense system in the liver of laying hens. A total of thirty-six, 24-week-old White leghorn hens were randomly assigned to a basal diet (CON) and that supplemented with a commercial lutein (LUT, 40 mg lutein /kg of diet) and the crude extract of spinach dissolved into oils with lecithin (ECE, 40 mg lutein/kg of diet) for 5 weeks. There was no difference in body weight and the relative live weight among dietary groups. The concentration of egg yolk lutein and yolk color significantly increased (P＜0.05) in the LUT and ECE groups compared with the CON group. The LUT group showed a higher yolk lutein and much a lower variability of average yolk lutein content, although there was no significant difference in egg yolk lutein content between the LUT and ECE groups. In antioxidant activity, the specific activity of hepatic superoxide dismutase (SOD) in the LUT group was significantly (P＜0.05) greater than that in the CON and ECE groups, whereas glutathione peroxidase (GPX) and glutathione Stransferase (GST) activities and lipid peroxidation were not affected by dietary sources of lutein. In conclusion, the dietary supplementation of lutein and the emulsified crude extract of spinach to laying hens resulted in a significant increase in the content of egg yolk lutein and yolk color, indicating that both supplements may potentially be applicable for the production of egg-enriched lutein in laying hens. This study also suggest that a commercial lutein more consistently produces the quality of lutein-enriched eggs and improves hepatic SOD activity compared with the emulsified crude extract of spinach.

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“…Carotenoids, which are present, have excellent antioxidant properties while α-and β-carotene, xanthophylls and retinoids have been reported to inhibit some types of cancers 4,5 . Lutein also shows greater antioxidant activity than the other two common carotenoids, β-carotene and lycopene 6 . Other Tagetes species that share some of these therapeutic properties include: T. patula 7 , T. minuta 8 .…”

Section: Introductionmentioning

confidence: 99%

Antinociceptive and Anti-Inflammatory Effects of Solvent Extracts of Tagetes erectus Linn (Asteraceae

Shinde¹,

Kanase²,

Shilimkar³

et al. 2009

Trop. J. Pharm Res

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Antioxidant activity, mutagenicity/anti-mutagenicity, and clastogenicity/anti-clastogenicity of lutein from marigold flowers

Cited by 113 publications

References 29 publications

Compositional Analysis of Lentil (Lens culinaris) Cultivars Related to Colors and Their Antioxidative Activity

Compositional Analysis of Lentil (Lens culinaris) Cultivars Related to Colors and Their Antioxidative Activity

Effects of Dietary Lutein Sources on Lutein-Enriched Egg Production and Hepatic Antioxidant System in Laying Hens

Antinociceptive and Anti-Inflammatory Effects of Solvent Extracts of Tagetes erectus Linn (Asteraceae

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