Antioxidant Activity of Ethanolic Fractions of Polish Propolis

Kurek-Górecka, Anna; Sobczakb, Andrzej; Rzepecka-Stojkod, Anna; Górecki, Michał; Wardas, Maria; Pawłowska-Góral, Katarzyna

doi:10.1515/znc-2012-11-1203

Cited by 15 publications

(3 citation statements)

References 19 publications

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“…The antioxidant activity of propolis has been widely studied; propolis varieties of different geographic locations have shown an antioxidant activity between 20% and 67% at the concentration of 20 µg/mL, showing that they are more active than our extract [46]. Kurek-Górecka et al [47] reported antioxidant activity of propolis at concentrations much higher than that used in our experiments. Finally, Bonamigo et al [48] reported antioxidant activity of propolis extracts with IC50 values between 50 and 180 µg/mL.…”

Section: Discussionmentioning

confidence: 48%

Bud-Poplar-Extract-Embedded Chitosan Films as Multifunctional Wound Healing Dressing

et al. 2022

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Wounds represent a major global health challenge. Acute and chronic wounds are sensitive to bacterial infection. The wound environment facilitates the development of microbial biofilms, delays healing, and promotes chronic inflammation processes. The aim of the present work is the development of chitosan films embedded with bud poplar extract (BPE) to be used as wound dressing for avoiding biofilm formation and healing delay. Chitosan is a polymer with antimicrobial and hydrating properties used in wound dressing, while BPE has antibacterial, antioxidative, and anti-inflammatory properties. Chitosan-BPE films showed good antimicrobial and antibiofilm properties against Gram-positive bacteria and the yeast Candida albicans. BPE extract induced an immunomodulatory effect on human macrophages, increasing CD36 expression and TGFβ production during M1/M2 polarization, as observed by means of cytofluorimetric analysis and ELISA assay. Significant antioxidant activity was revealed in a cell-free test and in a human neutrophil assay. Moreover, the chitosan-BPE films induced a good regenerative effect in human fibroblasts by in vitro cell migration assay. Our results suggest that chitosan-BPE films could be considered a valid plant-based antimicrobial material for advanced dressings focused on the acceleration of wound repair.

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Section: Discussionmentioning

confidence: 48%

Bud-Poplar-Extract-Embedded Chitosan Films as Multifunctional Wound Healing Dressing

et al. 2022

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“…CAPE is a flavonoid-like bioactive compound of propolis that specifically inhibits NF-κB activation [65]. Polyphenolic constituents found in propolis possess free radical scavenging activity against ROS [66], and the polyphenolic profile of propolis has a direct correlation with its antioxidant properties [67]. Tanaka et al reported that the suppressive effects of Brazilian propolis possess beneficial effects in a mouse model of RA and proposed that the suppressive effect results from a reduction in IL-17 production by blocking the differentiation of IL-17-secreting cells, also denoted as Th17 cells [68].…”

Section: Rheumatoid Arthritismentioning

confidence: 99%

Propolis and Their Active Constituents for Chronic Diseases

et al. 2023

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Propolis is a mass of chemically diverse phytoconstituents with gummy textures that are naturally produced by honeybees upon collection of plant resins for utilization in various life processes in beehives. Since ancient times, propolis has been a unique traditional remedy globally utilized for several purposes, and it has secured value in pharmaceutical and nutraceutical areas in recent years. The chemical composition of propolis comprises diverse constituents and deviations in the precise composition of the honeybee species, plant source used for propolis production by bees, climate conditions and harvesting season. Over 300 molecular structures have been discovered from propolis, and important classes include phenolic acids, flavonoids, terpenoids, benzofurans, benzopyrene and chalcones. Propolis has also been reported to have diverse pharmacological activities, such as antidiabetic, anti-inflammatory, antioxidant, anticancer, immunomodulatory, antibacterial, antiviral, antifungal, and anticaries. As chronic diseases have risen as a global health threat, abundant research has been conducted to track propolis and its constituents as alternative therapies for chronic diseases. Several clinical trials have also revealed the potency of propolis and its constituents for preventing and curing some chronic diseases. This review explores the beneficial effect of propolis and its active constituents with credible mechanisms and computational studies on chronic diseases.

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“…Pollen for winter supplies, which is deposited in the honeycomb cells, undergoes lactic fermentation and produces bee bread. Bee bread and bee pollen are bactericidal and bacteriostatic ethanol, and then the extract is concentrated in reduced pressure conditions [41]. An aqueous extract of propolis is used in antifungal cosmetics, while propolis dissolved in fats is used to produce lipsticks.…”

Section: Introductionmentioning

confidence: 99%

Bee Products in Dermatology and Skin Care

Kurek-Górecka¹,

et al. 2020

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Honey, propolis, bee pollen, bee bread, royal jelly, beeswax and bee venom are natural products which have been used in medicine since ancient times. Nowadays, studies indicate that natural bee products can be used for skin treatment and care. Biological properties of these products are related to flavonoids they contain like: chrysin, apigenin, kaempferol, quercetin, galangin, pinocembrin or naringenin. Several pharmacological activities of phenolic acids and flavonoids, and also 10-hydroxy-trans-2-decenoic acid, which is present in royal jelly, have been reported. Royal jelly has multitude of pharmacological activities: antibiotic, antiinflammatory, antiallergenic, tonic and antiaging. Honey, propolis and pollen are used to heal burn wounds, and they possess numerous functional properties such as: antibacterial, anti-inflammatory, antioxidant, disinfectant, antifungal and antiviral. Beeswax is used for production of cosmetics and ointments in pharmacy. Due to a large number of biological activities, bee products could be considered as important ingredients in medicines and cosmetics applied to skin.

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Antioxidant Activity of Ethanolic Fractions of Polish Propolis

Cited by 15 publications

References 19 publications

Bud-Poplar-Extract-Embedded Chitosan Films as Multifunctional Wound Healing Dressing

Bud-Poplar-Extract-Embedded Chitosan Films as Multifunctional Wound Healing Dressing

Propolis and Their Active Constituents for Chronic Diseases

Bee Products in Dermatology and Skin Care

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