Antioxidant activity of ethyl acetate extract of Ipomoea staphylina

Mohammad, Firdous Sayeed; Amartya, Banerjee; Karmakar, Varnita; Ghosh, Arya

doi:10.5958/0975-6892.2022.00015.6

Cited by 2 publications

(2 citation statements)

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“…These results are better than those of who obtained 1 an IC50 of 179 ± 0.81 μg/mL on the same HCT-116 cancer cell line using the methanolic extract of Eclipta alba. However, this result is less interesting to that of 14 16 .…”

Section: Discussioncontrasting

confidence: 58%

Cytotoxicity and antioxidant potential of dichloromethane and ethyl acetate extracts of Morinda morindoïdes leaves

TANOH,

KPOROU,

BRION

et al. 2024

J. Drug Delivery Ther.

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The incidence of cancer and related mortality are on the rise worldwide, and this requires the search for new plant-based medicines. In this study, the antioxidant potential and cytotoxic activity against HCT-116 cell line were evaluated. Dichloromethane and ethyl acetate extracts of M. morindoïdes were prepared by maceration and evaluated for some biological properties. Cytotoxicity was assessed according to MTS method on the cancer line HCT-116 (colorectal carcinoma) using doxorubicin as reference. Antioxidant potential was carried out by DPPH and ABTS tests. Tri-phytochemistry was carried out from coloring and precipitation tests. On HCT-116 cell line, extracts demonstrated dose-response activity. The lowest IC50 value was obtained with the acetate extract with an IC50= 16.38 ± 0.2 µg/mL. IC50 values for antioxidant activities were evaluated at 39.70 ± 1.7 µg/mL and at 57.65 ± 4.3µg/mL by DPPH and ABTS test respectilly. Finally, phytochemical screening showed presence of polyphenols, flavonoids and quinone. M. morindoides ethyl acetate extract showed the best cytotoxicity and antioxidant activities. Therefore, it should be an interesting source for discovery of new compounds for colorectal cancer treatment. Keywords: cytotoxicity, cancer cells, antioxidant, Morinda morindoides.

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Section: Discussioncontrasting

confidence: 58%

Cytotoxicity and antioxidant potential of dichloromethane and ethyl acetate extracts of Morinda morindoïdes leaves

TANOH,

KPOROU,

BRION

et al. 2024

J. Drug Delivery Ther.

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“…Ascorbic acid (4 mg ml -1 ) served as positive control. The antioxidant activity was calculated by comparing the changes in absorbance with respect to the positive control (7).…”

Section: B Antioxidant Activities 1) Determination Of Superoxide Radi...mentioning

confidence: 99%

Comparison of Antioxidant Activity of Some Antidiabetic Traditional Medicinal Plants of Madhya Pradesh, India

Soni

2023

IJRASET

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Traditional antidiabetic drugs are in use by a majority of patients having type II diabetes, due to their belief in traditional medicines. Here, we report the additional benefits of using such traditional plants in the diabetes therapy, so that these locally available medicines are promoted over synthetic drugs. Ten medicinal plants were chosen for the study, selected based on the traditional knowledge. The plant parts were extracted with water, methanol, ethyl acetate and petroleum ether. Antioxidant activity was determined by analyzing the potential of these extracts to scavenge superoxide, hydroxyl, nitrate, peroxide and 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radicals, under in vitro conditions as compared to the positive control; ascorbic acid (4 mg ml-1 ). Highest antioxidant activity was shown by extracts of Gymnema sylvestre, followed by Withania somnifera against all free radicals tested.

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Antioxidant activity of ethyl acetate extract of Ipomoea staphylina

Cited by 2 publications

References 0 publications

Cytotoxicity and antioxidant potential of dichloromethane and ethyl acetate extracts of Morinda morindoïdes leaves

Cytotoxicity and antioxidant potential of dichloromethane and ethyl acetate extracts of Morinda morindoïdes leaves

Comparison of Antioxidant Activity of Some Antidiabetic Traditional Medicinal Plants of Madhya Pradesh, India

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