Antioxidant activity of water and ethanol extracts from roots of Cassine transvaalensis Burtt-Davy from Botswana

Ethnobotanical Survey of Medicinal Plants of Tswapong North, in Eastern Botswana: A Case of Plants from Mosweu and Seolwane Villages

“…From historic time, the documentation of traditional knowledge especially on the medicinal uses of plants has provided many important drugs of modern day [8,9,10]. Traditional medicine still remains the main resource for majority (80%) of people in developing countries for treating health problems, particularly because medicinal plants are accessible and cheap [11,12]. Additionally, the use of medicinal plants by the Batswapong ethnic group is embedded within their culture.…”

Medicinal Uses, Phytochemistry and Pharmacological Properties of Elaeodendron transvaalense

“…Motlhanka et al [65] evaluated the antioxidant activities of water and ethanol root extracts of E. transvaalensis and a compound 4’-O-methyl-epigallocatechin, isolated from the species using the 2,2-dipheny-l-picrylhydrazyl (DPPH) free radical scavenging assay with quercetin, rutin, and ascorbic acid as positive controls. Above 100 µg/mL, the ethanolic extract showed an 80% scavenging activity, which was similar to the activities exhibited by the control antioxidant compounds quercetin, rutin, and ascorbic acid, and the water extract reached a similar of activity (80%) at 200 µg/mL (Table 4).…”

“…Between 25.0 µg/mL to 50 µg/mL, the compound 4’-O-methyl-epigallocatechin exhibited a 65% scavenging activity, which was greater than the activities exhibited by both water and ethanol extracts. But at concentrations above 50 µg/mL, the scavenging activity of the ethanol extract exceeded that of the compound 4’-O-methyl-epigallocatechin [65]. Motlhanka et al [39] evaluated the antioxidant activities of water and ethanol root extracts of E. transvaalensis and a compound 4’-O-methyl-epigallocatechin, isolated from the species, using the DPPH free radical scavenging assay with quercetin, rutin, and ascorbic acid as positive controls.…”

Triterpenoids

“…270 2,3-Secofriedel-1-en-3-oic acid 462, 3b-hydroxyfriedelan-23oic acid 463 and 1b-hydroxyfriedelan-3-one 464 have been isolated from Garcia parviflora. 287 Ursane saponins with known genins include 23-O-acetylmadecassoside from Centella asiatica, 206 and saponins from Actinidia chinensis, 55 Centella erecta, 288 Commiphora gladulosa, 289 Gentiana loureirii 290 and Schefflera actinophylla. An unusual oxetane ring is present in 3b,23-epoxyfriedelan-28-oic acid 465, from Calophyllum inophyllum.…”

“…286 Reticulataursenoside is an ursane saponin, from fruit peel of Citrus reticulata, with the new genin 508 34 and ilexpublesnins A and B, from Ilex pubescens, have the new genin 509. 287 Ursane saponins with known genins include 23-O-acetylmadecassoside from Centella asiatica, 206 and saponins from Actinidia chinensis, 55 Centella erecta, 288 Commiphora gladulosa, 289 Gentiana loureirii 290 and Schefflera actinophylla. 170 Taraxast-20-ene-3b,12b,16b-triol 510 and the related ester 511 have been found in fruit of Cicuta virosa var.…”