Antioxidant and Antidiabetic Activity of Aqueous Extract of Myrtus Communis L. Berries on Streptozotocin-Induced Diabetic Rats

Demir, Galip Mesut; Gülaboğlu, Mine; Ağgül, Ahmet Gökhan; Baygutalp, Nurcan Kılıç; Canayakin, Doğukan; Halıcı, Zekai; Süleyman, Halis

doi:10.9790/3008-1105011116

Cited by 4 publications

(3 citation statements)

References 28 publications

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“…It was seen more in hepatic cells homogenates for action against ferric-nitrilotriacetate-induced lipid peroxidation than in cytotoxicity cell cultures for TBH inhibition or oxidation of induced FeCl 3 . The overall effects confirmed that semi myrtucommulone was a novel dietary antioxidant lead (Demir et al 2016 ).…”

Section: Antioxidant Effectsupporting

confidence: 72%

The therapeutic value of Myrtus communis L.: an updated review

Al-Snafi,

Teibo,

Shaheen

et al. 2024

Naunyn-Schmiedeberg's Arch Pharmacol

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Myrtus communis L. (Family: Myrtaceae) is naturally found in the western part of Asia, Southern Europe, and North Africa. It has been reportedly applied in pharmaceutical industry, traditional medicine, cosmetics, spices, and food. Pubmed, Google scholar, Web of Science, and Scopus were utilized to seek out relevant content concerning the therapeutic potential of M. communis. Subsequently, we conducted a review to identity noteworthy updates pertaining to M. communis. Myrtle berries, leaves, seeds, and essential oils are natural sources of several nutrients and bioactive compounds with marked health effects. The chemical analysis showed that M. communis contained oils, alkaloids, flavonoids, phenolics, coumarins, saponosides, tannins, quinines, and anthraquinones. A pharmacological investigation revealed that M. communis possessed anti-inflammatory, analgesic, antimicrobial, antiparasitic, antioxidant, antidiabetic, anticancer, antimutagenic, immunomodulatory, dermatological, cardiovascular, central nervous system, and gastrointestinal protective effects, among numerous other biological effects. This current review focused on the biochemical, pharmacological, therapeutic effects, and various biological activities of different parts of M. communis. It signifies that M. communis is a therapeutic plant with numerous applications in medicine and could be used as a drug isolate based on its safety and effectiveness.

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Section: Antioxidant Effectsupporting

confidence: 72%

The therapeutic value of Myrtus communis L.: an updated review

Al-Snafi,

Teibo,

Shaheen

et al. 2024

Naunyn-Schmiedeberg's Arch Pharmacol

View full text Add to dashboard Cite

show abstract

“…Myrtle fruits were extracted and given to experimental animals in different doses. It was observed that different doses of extracts decreased blood glucose levels (Demir et al, 2011). Similarly, in a study conducted on rats, it was reported that murt leaf extraction decreased blood glucose levels (Baz, 2014).…”

Section: Resultsmentioning

confidence: 89%

Investigation of Antioxidant Activities and Hypoglycemic Effect of Black and White Myrtle Fruits

Yegin

Güder

2021

Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi

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Fruits, are in black or white colour Mrytus communis, is known as locally name murt, hambales, mersin. It is an aromatic and medicinal plant that grows naturally in maquis form in regions with Mediterranean climate. In this research, we aimed to investigate the hypoglycemic effect and antioxidant activity of Myrtus communis L. White-black myrtle were collected from Hassa-Hatay and Tarsus-Mersin, respectively in October. Fruits were separated from the leaves and dried in the oven at 40ºC. Fruit extracts were obtained in absolute ethanol (1:15) by using magnetic stirrer at the room temperature for one day. In this study, radical scaving activity-(DPPH), the hydrogen peroxide scavenging activity-(HPSA), metal chelating activity-(MCA), ferric reducing antioxidant power activity-(FRAP), total phenol-flavonoid contents and α-amylase, α-glycosidase inhibition were examined to determine characteristics of samples. DPPH and HPSA values were expressed as µg/ml in terms of SC50. FRAP and MCA features of extract were given as % activity. The hypoglycemic effect was investigated with α-amylase, α-glucosidase inhibition assays.

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“…Almost every radical species can interact with another radical or molecule through different mechanisms. The selectivity of these interactions depends on the concentration of radicals, the localization of unpaired electrons in the radical, and the presence of weak bonds in the molecules that radicals interact with (Perkins et al, 1996;Demir et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Determination of Antioxidant Activity of The Leaves of Hawthorn (Crataegus Monogyna)

DİKİCİ,

KÖKSAL

2023

Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi

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This study was carried out to make decision the antioxidant activity of the leaves of hawthorn (Crataegus monogyna), which is a natural source of antioxidants. For this purpose, the leaves of hawthorn were collected and dried, and an ethanol extract was prepared. Total antioxidant activity (with respect to the ferric thiocyanate method), ion reduction capacity of Cu2+ (copper method), and Fe3+ (potassium ferricyanide reduction method) were determined on the prepared ethanol extracts. Additionally, scavenging activity of DPPH (1,1-diphenyl-2-picrylhydrazyl) and determination of the total phenolic-flavonoid compound content were carry out. The extracts obtained from Hawthorn (Crataegus monogyna) leaves were found to inhibit lipid peroxidation (of linoleic acid emulsion) by 40.9%. This inhibition occurred at a concentration of 10 µg/mL of the extracts. At the similar concentration, BHT exhibited 68.3% inhibition, while trolox exhibited 29.9% inhibition. Hawthorn (Crataegus monogyna), which was found to have a higher total phenolic content than trolox, exhibited significant DPPH scavenging and metal reduction activities. During the investigation of the antioxidant activity of the ethanol extract obtained from Crataegus monogyna, α-tocopherol, its water-soluble analogue trolox and BHT (butylated hydroxytoluene) were utilized as reference antioxidant compounds.

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Antioxidant and Antidiabetic Activity of Aqueous Extract of Myrtus Communis L. Berries on Streptozotocin-Induced Diabetic Rats

Cited by 4 publications

References 28 publications

The therapeutic value of Myrtus communis L.: an updated review

The therapeutic value of Myrtus communis L.: an updated review

Investigation of Antioxidant Activities and Hypoglycemic Effect of Black and White Myrtle Fruits

Determination of Antioxidant Activity of The Leaves of Hawthorn (Crataegus Monogyna)

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