Antioxidant and antifungal activities of a new chemovar of cumin (Cuminum cyminum L.)

Ghasemi, Ghader; Fattahi, Mohammad; Alirezalu, Abolfazl; Ghosta, Youbert

doi:10.1007/s10068-018-0506-y

Cited by 34 publications

(22 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Phytochemical analysis of C. cyminum has revealed the presence of alkaloids, anthraquinones, coumarins, flavonoids, glycosides, resins, saponins, tannins and steroids [ 159 ]. Cumin seed essential oil has been analyzed using GC-MS analysis and the presence of 18 compounds demonstrated, with 3-caren-10-al and cuminal being the main constituents [ 160 ]. A previous study has investigated the antioxidant activity of alcoholic and aqueous extracts of cumin seeds.…”

Section: Herbal Infusions Antioxidant and Anticancer Capacitiesmentioning

confidence: 99%

The Impact of Herbal Infusion Consumption on Oxidative Stress and Cancer: The Good, the Bad, the Misunderstood

et al. 2020

View full text Add to dashboard Cite

The release of reactive oxygen species (ROS) and oxidative stress is associated with the development of many ailments, including cardiovascular diseases, diabetes and cancer. The causal link between oxidative stress and cancer is well established and antioxidants are suggested as a protective mechanism against cancer development. Recently, an increase in the consumption of antioxidant supplements was observed globally. The main sources of these antioxidants include fruits, vegetables, and beverage. Herbal infusions are highly popular beverages consumed daily for different reasons. Studies showed the potent antioxidant effects of plants used in the preparation of some herbal infusions. Such herbal infusions represent an important source of antioxidants and can be used as a dietary protection against cancer. However, uncontrolled consumption of herbal infusions may cause toxicity and reduced antioxidant activity. In this review, eleven widely consumed herbal infusions were evaluated for their antioxidant capacities, anticancer potential and possible toxicity. These herbal infusions are highly popular and consumed as daily drinks in different countries. Studies discussed in this review will provide a solid ground for researchers to have better understanding of the use of herbal infusions to reduce oxidative stress and as protective supplements against cancer development.

show abstract

Section: Herbal Infusions Antioxidant and Anticancer Capacitiesmentioning

confidence: 99%

The Impact of Herbal Infusion Consumption on Oxidative Stress and Cancer: The Good, the Bad, the Misunderstood

et al. 2020

View full text Add to dashboard Cite

show abstract

“…These products if not controlled can be detrimental, affecting cell viability and leading to apoptosis that causes DM and associated neuropsychological disorders. This susceptibility of human brain is due to the presence of abundant amounts of polyunsaturated fatty acids (Starowicz and Zieliński, 2019) and high expression of insulin receptors (IR) on neurons and glia (Ghasemi et al, 2019). The highly expressed regions of brain for IR are documented to be in the hypothalamus, hippocampus, cerebral cortex, and olfactory bulb (Radünz et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

“…The global epidemic emergence of DM has encouraged concerted efforts in drug discovery from natural plant sources for efficient, cost-effective treatment modalities with minimum side effects (Mallick et al, 2016). Previous studies have shown the medicinal reputation of herbs which is long-established through their utility in treatment of various ailments (Mallick et al, 2016;Ghasemi et al, 2019). Many of these herbs are natural edibles and in south Asian households they are consumed daily in diet to enhance aroma, color, and flavor of the food (Uhm et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

In-vitro antioxidant potential of conventional herbal decoction aiding diabetes metabolomics

Saara¹,

Rafiq²,

Asra³

et al. 2022

Int. J. Med. Med. Sci.

View full text Add to dashboard Cite

Diabetes mellitus (DM) is a risk factor of oxidative stress through the production of reactive oxygen species (ROS). ROS triggers cell damage which enhances the risk of several diabetes associated disorders such as neuropathy. There are many treatment options but no cure, and the quest for the natural, cost-effective treatment regimen is ongoing. Therefore, the present study was conducted to observe the in-vitro antioxidant and anti-cholinesterase activities of the indigenous natural herbs Zingiber officinale (Ginger), Cinnamomum verum (daarcheeni), Piper nigrum (Black pepper), and Syzygium aromaticum (clove). Herbal decoctions were prepared and in-vitro biochemical analysis were done of the antioxidant potential of herbs by inhibition of catalase (CAT), superoxide dismutase (SOD) enzymes with lowering of 2,2-diphenyl-1-picrylhydrazyl (DPPH) and Malondialdehyde (MDA) concentration. Moreover, spectrophotometric percentage inhibition of acetylcholine-esterase (AChE) and butyrylcholine-esterase (BChE) enzymes by the herbs was also measured. It was observed that herbal decoctions possess strong antioxidant activities especially Z. officinale decoction with significant percentage inhibition of enzymes with lowering of DPPH and MDA levels. Hence, herbal decoctions with potential antioxidant scavenging activities can be used to ameliorate progression of DM and associated psychoneurological disorders.

show abstract

“…[4] For example, the mycelium growth of B. cinerea, Aspergillus flavus and Penicillim expansum was completely inhibited by CEO treatment. [9] In addition, CEO increased the permeability of Escherichia coli and Listeria innocua cells and destroyed the integrity of their cell membranes. [10] The present study was conducted to investigate the inhibitory effect of CEO and its main compounds on seven fungi-related P. notoginseng diseases and to evaluate the possible targets by scanning electron microscopy (SEM) and transmission electron microscopy (TEM).…”

Section: Introductionmentioning

confidence: 99%

“…In traditional medicine, CEO has been considered a stimulant and promoter and has been used in many respects, [6,8] and according to numerous reports, also has strong agricultural antibacterial activity [4] . For example, the mycelium growth of B. cinerea , Aspergillus flavus and Penicillim expansum was completely inhibited by CEO treatment [9] . In addition, CEO increased the permeability of Escherichia coli and Listeria innocua cells and destroyed the integrity of their cell membranes [10] .…”

Section: Introductionmentioning

confidence: 99%

Chemical Constituents of the Essential oil fromCuminum cyminumL. and Its Antifungal Activity againstPanax notoginsengPathogens

Huo

Yang

et al. 2021

Chemistry & Biodiversity

View full text Add to dashboard Cite

Cuminum cyminum L. (Cumin) is a flavoring agent that is commonly used worldwide, and is rich in essential oil. Essential oils (Eos) have been intensively investigated in regard to their potential for disease control in plants, which is provided a chance for the blossom of green pesticides. The chemical components of Cumin essential oil (CEO) were revealed by GC/MS, such as cuminaldehyde (44.53 %), p-cymene (12.14 %), (À )-β-pinene (10.47 %) and γ-terpinene (8.40 %), and found they can inhibit the growth of P. notoginseng-associated pathogenic fungi in vitro and the inhibitory effect of cuminaldehyde was similar to that of hymexazol. SEM and TEM images demonstrated that cuminaldehyde and CEO increased cell permeability and disrupted membrane integrity. The expression of disease-related genes of Fusarium oxysporum showed that CEO induced the expression of most genes, which disrupted biosynthesis, metabolism and signaling pathways. These studies verified the potential of CEO as a plant fungicide that is environmentally friendly and provided ideas for developing new products for controlling root diseases that affect P. notoginseng.

show abstract

Antioxidant and antifungal activities of a new chemovar of cumin (Cuminum cyminum L.)

Cited by 34 publications

References 35 publications

The Impact of Herbal Infusion Consumption on Oxidative Stress and Cancer: The Good, the Bad, the Misunderstood

The Impact of Herbal Infusion Consumption on Oxidative Stress and Cancer: The Good, the Bad, the Misunderstood

In-vitro antioxidant potential of conventional herbal decoction aiding diabetes metabolomics

Chemical Constituents of the Essential oil fromCuminum cyminumL. and Its Antifungal Activity againstPanax notoginsengPathogens

Contact Info

Product

Resources

About