Antioxidant and antigenotoxic activity of bioactive extracts from corn tassel

Wang, Lichun; Yu, Yewei; Fang, Min; Zhan, Cai-gui; Pan, Hong-yan; Wu, Yongning; Gong, Zhiyong

doi:10.1007/s11596-014-1244-x

Cited by 11 publications

(9 citation statements)

References 25 publications

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“…A level of probability was accepted significantly when the p value was below 0.05. 36,39,40 Additionally, the NP characterization results are also presented as the mean ± SD of the triplicate measurement.…”

Section: ■ Materials and Methodsmentioning

confidence: 99%

Assessment of the Antigenotoxic Activity of Poly(d,l-lactic-co-glycolic acid) Nanoparticles Loaded with Caffeic Acid Phenethyl Ester Using the Ames Salmonella/Microsome Assay

Arasoğlu

Derman

2018

J. Agric. Food Chem.

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In the present study, the antigenotoxic activity of poly(d,l-lactic- co-glycolic acid) (PLGA) nanoparticles (NPs) loaded with caffeic acid phenethyl ester (CAPE) was investigated in comparison to free CAPE using the Ames Salmonella/microsome assay. Additionally, to elucidate the impacts of the type of solvent effect on antigenotoxic activity, the following systems were tested: CAPE in water (poor solvent), ethyl alcohol (good solvent), and PLGA NPs (unknown). The effect of the NP system on solubility was investigated for the first time by assessing the antigenotoxic potential. In this study, the CAPE/PLGA NPs were synthesized using an oil-in-water (o/w) single-emulsion solvent evaporation method with an average size of 206.2 ± 1.2 nm, ζ potential of -19.8 ± 2.5 mV, encapsulation efficiency of 87.2 ± 2.5%, and drug loading of 53.3 ± 1.8%. According to the results of the antigenotoxic activity, the highest antimutagenic activity in both applied strains was found for CAPE in ethanol, and the lowest activity was detected for CAPE in water. Our study has shown that NP systems exhibit high antigenotoxic activity, which is similar to the results of CAPE dissolved in ethanol. These results have shown that NP systems increase biological activity of hydrophobic substances by increasing their solubility and that the use of PLGA instead of organic solvents in drug production may provide an increase in their medical utility.

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Section: ■ Materials and Methodsmentioning

confidence: 99%

Assessment of the Antigenotoxic Activity of Poly(d,l-lactic-co-glycolic acid) Nanoparticles Loaded with Caffeic Acid Phenethyl Ester Using the Ames Salmonella/Microsome Assay

Arasoğlu

Derman

2018

J. Agric. Food Chem.

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“…In this work, the authors proved that CA and FA can be considered as effective fungitoxicants for A. flavus and A. parasiticus in in vitro assay. Wang et al (2014) evaluated antioxidant and antigenotoxic activities of corn tassel extracts (CTTs). The major bioactive compounds belonged to flavonoids (1.67%), saponins (2.41%) and polysaccharides (4.76%) group.…”

Section: Herbaceous Energy Cropsmentioning

confidence: 99%

Phytochemicals in bioenergy crops

2019

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The use of natural compounds derived from agricultural crops and other plants as health promoting chemicals gains tremendous growing interest in various industrial sectors as well as among people worldwide. These chemicals have been more and more employed by the food industry as food additives, functional food ingredients, nutraceuticals, by feedstuffs industry, but also by the cosmetic and pharmaceutical industries. The general idea for this interest is to use natural products as potential alternatives to synthetic chemicals. On the other hand, some plants characterized by high yield and being used as energy crops also contained significant amount of bioactive compounds. This review focuses on the wide spectrum of the phytochemicals present in available biomass plants. It is supposed that extraction of bioactive chemicals from energy crops before their energetic use may increase economical effectiveness, providing simultaneously a double benefit in the form of phytochemicals and bioenergy as value added products. This remains in line with bioeconomy, which is defined by European Commission as ''the production of renewable biological resources and the conversion of these resources and waste streams into value added products, such as food, feed, bio-based products and bioenergy''. However, the issue is still a challenging effort due to the high costs, technology readiness and regulatory hurdles.

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“…Corn tassel has been used as a traditional medicine in China [20]. The authors also reported that flavonoids, saponin and polysaccharide from corn tassel could inhibit the proliferation of MGC80-3 gastric cancer cells in vitro.…”

Section: Introductionmentioning

confidence: 98%

Variability in Anthocyanins, Phenolic Compounds and Antioxidant Capacity in the Tassels of Collected Waxy Corn Germplasm

et al. 2019

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Corn tassel is a valuable co-product and an excellent source of phytochemicals with bioactive properties. The information on the genetic diversity in the tassel properties of waxy corn germplasm is important for creating new varieties that can have the potential for the commercial production of tassels as a co-product. Therefore, the objective of this study was to evaluate the potential of corn tassels in a set of waxy corn germplasm for the extraction of phenolic compounds with an antioxidant activity. The experiment was carried out under field conditions in the rainy season 2017 and the dry season 2017/2018. Fifty waxy corn genotypes were evaluated. Data were collected for the total anthocyanin content (TAC), total phenolic content (TPC) and the antioxidant activity was determined by the 2,2-diphenyl−1-picrylhydrazyl (DPPH) radical scavenging activity and Trolox equivalent antioxidant capacity (TEAC) assays. The season (S) had small effect on all of the parameters, accounting for 0.2–8.7% of the total variance. The genotype (G) was the largest variance component in the TAC and DPPH radical scavenging activity, accounting for 83.5–97.5% of the total variance. The G and S × G interaction contributed approximately equally to the total variance in the TPC and TEAC. Based on the TAC, TPC and antioxidant capacity variation, the genotypes were classified into seven groups. The tassels of corn genotypes belonging to three of these clusters (clusters E, F and G) had high levels of phytochemicals along with an antioxidant capacity. A significant correlation coefficient was found between the TAC and DPPH (r = 0.70 **). The TPC showed a moderate relationship with the DPPH and TEAC assays (r = 0.60 ** and 0.76 **, respectively). The information obtained from this study can be used for germplasm management and waxy corn breeding for enhancing levels of bioactive properties in waxy corn tassels.

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Antioxidant and antigenotoxic activity of bioactive extracts from corn tassel

Cited by 11 publications

References 25 publications

Assessment of the Antigenotoxic Activity of Poly(d,l-lactic-co-glycolic acid) Nanoparticles Loaded with Caffeic Acid Phenethyl Ester Using the Ames Salmonella/Microsome Assay

Assessment of the Antigenotoxic Activity of Poly(d,l-lactic-co-glycolic acid) Nanoparticles Loaded with Caffeic Acid Phenethyl Ester Using the Ames Salmonella/Microsome Assay

Phytochemicals in bioenergy crops

Variability in Anthocyanins, Phenolic Compounds and Antioxidant Capacity in the Tassels of Collected Waxy Corn Germplasm

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