Antioxidant and Health Properties of Beehive Products Against Oxidative Stress-Mediated Carcinogenesis

Al-Lawati, Hassan Talib; Al-Ajmi, Hajar Ibrahim Salim; Waly, Mostafa I.

doi:10.1007/978-3-319-75693-6_7

Cited by 2 publications

(1 citation statement)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Through pollination, insects are responsible for a global service worth $215 billion to food production (Goulson et al ., 2015). This insect brings huge economic benefits for beekeepers by providing bee products which are not only used as edible products but also as components of medicines in clinical treatments (Al-Lawati et al ., 2018). For these reasons, bees are extremely important for humans and the environment and should be preserved.…”

Section: Introductionmentioning

confidence: 99%

Piperine as a new natural supplement with beneficial effects on the life-span and defence system of honeybees

et al. 2019

View full text Add to dashboard Cite

Many factors, including pathogens, environmental change and breeding techniques, affect honeybee immunity/resistance, so substances and natural supplements that enhance it are desired. To eliminate the impact of unknown external factors, in 2016 a cage experiment was conducted under constant laboratory conditions (35 °C, 65% relative humidity). Bees in the control group were fed with sugar dissolved in water at ratio 1:1 ad libitum with no additives, while the other group was fed with sugar syrup (1:1) supplemented with piperine (3 µg/ml) ad libitum. The piperine-treated workers lived 9 days longer compared to the control group. In the piperine-consuming group, protein concentration and the activities of antioxidative enzymes, such as superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT) and glutathione S-transferase (GST), were higher than in the control group. The activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP) were also higher in the piperine-treated group. Neutral and acidic proteases inhibitors, as well as neutral protease activities, were higher in the haemolymph of the piperine-treated workers than in untreated bees. Acidic protease activities in the haemolymph were higher in untreated workers only on days 18 and 32. Alkaline protease activities in the control bees were higher from day 10. From 10 days old, the total antioxidant capacity level was significantly higher in the haemolymph of piperine-treated workers. Piperine decreased DNA methylation levels significantly in the older bees. The compound could have the potential to be a natural diet supplement increasing apian resistance to stress factors.

show abstract

Section: Introductionmentioning

confidence: 99%