Antioxidant and Protective Effects of Artemisia campestris Essential Oil Against Chlorpyrifos-Induced Kidney and Liver Injuries in Rats

Saoudi, Mongi; Badraoui, Riadh; Rahmouni, Fatma; Jamoussi, Kamel; Feki, Abdelfattah El

doi:10.3389/fphys.2021.618582

Cited by 25 publications

(12 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The protective effect of A. campestris essential oil could be attributed to its anti-oxidant potential. Similar results were obtained by Saoudi et al 16 who determined the protective effect of A. campestris essential oil against chlorpyrifos-induced kidney injury in rats. Akrout et al 63 found that A. campestris essential oil was dominated by β-pinene, p-cymene, and α-pinene.…”

Section: Artemisia Campestrissupporting

confidence: 89%

Tunisian Nephroprotective Plants: A Review

Wannes¹,

Tounsi²

2022

J Explor Res Pharmacol

View full text Add to dashboard Cite

In Tunisian folk medicine, several herbs are prescribed for reducing renal damage and to avoid kidney related complications. These can be of immense value in combating renal damage. In this review, we provide a description of the current literature on the use of indigenous herbs as alternative medicine for treating renal damage. The aim of this review was to collect information on promising active phytoconstituents such as organosulfur compounds, polyphenols, terpenes, alkaloids phenylpropanoids, and polysaccharides from Tunisian plants that have been scientifically examined for their nephroprotective capacities. Twenty-nine Tunisian medicinal plants have been reported for their significant nephroprotective activities against renal toxicities in animal models. Lamiaceae was the most commonly used Tunisian plant family used for renal protection. The leaves were maximally used for nephroprotection compared to the other plant parts. Nephrotoxicity is commonly the result of several nephrotoxins. Many studies have focussed on drug-caused renal failure which is one of the major problems in medical practice. Other studies focused on other important nephrotoxicity factors, including drugs and industrial chemicals. This literature review highlights the use of some medicinal plants as nephroprotective agents. To defend against this nephrotoxicity, some medicinal plants, known as nephroprotective agents, have been highlighted in this review.

show abstract

Section: Artemisia Campestrissupporting

confidence: 89%

Tunisian Nephroprotective Plants: A Review

Wannes¹,

Tounsi²

2022

J Explor Res Pharmacol

View full text Add to dashboard Cite

show abstract

“…Over the years, medicinal plants have been used to develop a variety of formulations that combat injuries such as wounds, burns and cuts [ 15 ]. Several ethno-medicinal plants have been used for medicinal applications thanks to their wide biological activities and medicinal applications due to counteracting oxidative stress potential, lesser costs and high safety margins [ 16 , 17 , 18 ]. Plant extracts are known to exhibit many pharmacological properties (anti-hyperlipidemic, anti-proliferative, and immunomodulatory, etc.)…”

Section: Introductionmentioning

confidence: 99%

“…Plant extracts are known to exhibit many pharmacological properties (anti-hyperlipidemic, anti-proliferative, and immunomodulatory, etc.) through the multitude amounts of natural polyphenolic antioxidants [ 17 , 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

The Role of Allium subhirsutum L. in the Attenuation of Dermal Wounds by Modulating Oxidative Stress and Inflammation in Wistar Albino Rats

et al. 2021

Self Cite

View full text Add to dashboard Cite

In our study, Allium subhirsutum L. (AS) was investigated to assess its phenolic profile and bioactive molecules including flavonoids and organosulfur compounds. The antioxidant potential of AS and wound healing activity were addressed using skin wound healing and oxidative stress and inflammation marker estimation in rat models. Phytochemical and antiradical activities of AS extract (ASE) and oil (ASO) were studied. The rats were randomly assigned to four groups: group I served as a control and was treated with simple ointment base, group II was treated with ASE ointment, group III was treated with ASO ointment and group IV (reference group; Ref) was treated with a reference drug “Cytolcentella® cream”. Phytochemical screening showed that total phenols (215 ± 3.5 mg GAE/g) and flavonoids (172.4 ± 3.1 mg QE/g) were higher in the ASO than the ASE group. The results of the antioxidant properties showed that ASO exhibited the highest DPPH free radical scavenging potential (IC50 = 0.136 ± 0.07 mg/mL), FRAP test (IC50 = 0.013 ± 0.006 mg/mL), ABTS test (IC50 = 0.52 ± 0.03 mg/mL) and total antioxidant capacity (IC50 = 0.34 ± 0.06 mg/mL). In the wound healing study, topical application of ASO performed the fastest wound-repairing process estimated by a chromatic study, percentage wound closure, fibrinogen level and oxidative damage status, as compared to ASE, the Cytolcentella reference drug and the untreated rats. The use of AS extract and oil were also associated with the attenuation of oxidative stress damage in the wound-healing treated rats. Overall, the results provided that AS, particularly ASO, has a potential medicinal value to act as effective skin wound healing agent.

show abstract

“…Artemisia herbs contain hundreds of bioactive molecules including artemisinin and its derivatives that were effectively used to counteract malaria (Bora, Sharma, 2011;Kursat et al, 2015;Lis, Kowal, 2015;Nigam et al, 2019). These substances were actually reported to be potentially effective against several health problems (Kursat et al, 2015;Saoudi et al, 2017;Saoudi et al, 2021). Interestingly, the screening of Artemisia extracts proved that many derivatives such as artemisinin, kaempferol and rutin, and whole aerial parts extracts of Artemisia species exert virucidal effects against diverse types of viruses, including coronaviruses (Arbab et al, 2017 al., 2017;Cheng et al, 2004;D'Alessandro et al, 2020;Han et al, 2015;Ivanescu, Miron, Corciova, 2015;Kim, Jeon, Ko, 2001;Lai et al, 2007;Li et al, 2005;Lubbe et al, 2012;Ma, Nakamura, Hattori, 2001;McCutcheon et al, 1995;Mitrocotsa et al, 2000;Romero et al, 2006;Sinico et al, 2005).…”

Section: Antiviral Potential Of Artemisia Herbsmentioning

confidence: 99%

Approach of utilizing Artemisia herbs to treat covid-19

Ben-Nasr

Badraoui

2022

Braz. J. Pharm. Sci.

View full text Add to dashboard Cite

Huge plethora of studies pointed out the importance of several Artemisia herb molecules as treatment for many diseases. Among these natural substances, some molecules are known to counteract fever, inflammation, blood clotting and oxidative stress. Furthermore, they are dotted with activities against different strains of viruses including the SARS-coronaviruses. For these beneficial properties, these medicinal herbs are deemed as a potential candidate for covid-19 pandemic.

show abstract

Antioxidant and Protective Effects of Artemisia campestris Essential Oil Against Chlorpyrifos-Induced Kidney and Liver Injuries in Rats

Cited by 25 publications

References 42 publications

Tunisian Nephroprotective Plants: A Review

Tunisian Nephroprotective Plants: A Review

The Role of Allium subhirsutum L. in the Attenuation of Dermal Wounds by Modulating Oxidative Stress and Inflammation in Wistar Albino Rats

Approach of utilizing Artemisia herbs to treat covid-19

Contact Info

Product

Resources

About